NIDCR Clinical Research Protocols

NIDCR conducts clinical studies on the NIH campus in Bethesda, Maryland. Currently, NIDCR-supported clinical trials are open or will soon be open for patient recruitment at the NIH Clinical Center. Below is a list of all clinical research protocols, including studies that are not open for recruitment.

Protocol	ClinicalTrials.gov Study Title	PI	Contact Person	NCT Number	Recruitment Status
01-D-0184	Evaluation and Treatment of Skeletal Diseases	Gafni, Rachel	Karen A Pozo, R.N. (301) 827-1138 karen.pozo@nih.gov	NCT00024804	Recruiting
11-D-0172	The Pathogenesis and Natural History of Sjogren s Syndrome	Warner, Blake	Eileen M Pelayo (301) 594-3097 eileen.pelayo@nih.gov Blake M Warner, D.D.S. (301) 500-8063 blake.warner@nih.gov	NCT01425892	Recruiting
12-D-0100	Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)	Moutsopoulos, Niki	Laurie D Brenchley (301) 451-2551 laurie.brenchley@nih.gov Niki M Moutsopoulos, D.D.S. (301) 435-7182 nmoutsop@mail.nih.gov	NCT01568697	Recruiting
13-D-0033	Tooth and Tissue Sample Collection During Wisdom Teeth Removal	Lee, Janice	NIH Clinical Center contact Office of Patient Recruitment (OPR) (800) 411-1222 ext TTY8664111010 prpl@cc.nih.gov Danielle Elangue (301) 451-9733 danielle.elangue@nih.gov	NCT01805869	Recruiting
15-D-0051	Characterization of Diseases With Salivary Gland Involvement	Warner, Blake	Contact: Eileen M Pelayo (301) 594-3097 eileen.pelayo@nih.gov Blake M Warner, D.D.S. (301) 500-8063 blake.warner@nih.gov	NCT02327884	Recruiting
15-D-0129	Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction	Chiorini, Jay	Katherine Hall, R.N., MSN (301) 402-6905 hallkm@nih.gov John A Chiorini, Ph.D. (301) 496-4279 jchiorin@nih.gov	NCT02446249	Recruiting
16-D-0040	Natural History of Craniofacial Anomalies and Developmental Growth Variants	Lee, Janice	Pamela M Orzechowski, R.N. (301) 402-7373 ps363q@nih.gov	NCT02639312	Recruiting
18-D-0114	Denosumab Treatment for Fibrous Dysplasia	Boyce, Alison	Active, not recruiting	NCT03571191	Closed to Recruitment
18-D-0121	Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls	Mays, Jacqueline	Licia Masuch (301) 435-9352 licia.masuch@nih.gov	NCT03602599	Recruiting
20-D-0094	Transmissibility and Viral Load of SARS-CoV-2 in Oral Secretions	Warner, Blake	Closed to enrollment; in data analysis	NCT04348240	Closed to Recruitment
20-D-0122	Safety, Tolerability, and Efficacy of CLTX-305 in Participants With Autosomal Dominant Hypocalcemia (ADH) Type 1	Gafni, Rachel	Active, not recruiting	NCT04581629	Closed to Recruitment
20-D-0131	Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome	Warner, Blake	Sasha Clary, (301) 529-7924 sasha.clary@nih.gov	NCT04496960	Recruiting
98-D-0145	Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome	Boyce, Alison	Lori C Guthrie, R.N. (301) 594-0844 guthriel@mail.nih.gov Alison M Boyce, M.D. (301) 827-4802 alison.boyce@nih.gov	NCT00001727	Recruiting