On July 29, Agnes Binagwaho, MD, Minister of Health of the Republic of Rwanda, will deliver the 2015 David E. Barmes Global Health Lecture on the NIH campus in Bethesda, Maryland. Her lecture is called "Medical Research and Capacity Building for Development: The Experience of Rwanda." NIDCR and the Fogarty International Center are cosponsoring the event. The David E. Barmes Global Health Lecture series honors the late David Edward Barmes, who was NIDCR’s special expert for international health. The lecture, which is free and open to the public, will be webcast live and archived.
In April, Janice S. Lee, DDS, MD, MS, was appointed as the clinical director of NIDCR’s Division of Intramural Research. Dr. Lee, a board-certified oral and maxillofacial surgeon, joined NIDCR as the deputy clinical director in August 2013, after a decade at the University of California, San Francisco. NIDCR Director Martha J. Somerman, DDS, PhD, said, “In the short time she has been intramural deputy clinical director, Dr. Lee has distinguished herself as an outstanding leader with a deep comprehension of the importance of basic research as well as the tireless dedication to translating preclinical research results into protocols for clinical studies.” Dr. Lee’s clinical and translational research program is exploring the natural history and genetic etiology of craniofacial anomalies and growth abnormalities.
In April, James E. Melvin, DDS, PhD, became the new deputy scientific director in the Division of Intramural Research. Dr. Melvin joined NIDCR in 2010 as the clinical director. “Dr. Melvin’s outstanding leadership during his five-year tenure has made a difference in the lives of the patients who visit our dental clinic, and in the lives and careers of the clinical fellows who are trained and mentored here,” said Dr. Somerman. “We are extremely fortunate to have a leader with Dr. Melvin’s versatility to transition from the administration of our clinical research to our basic research program.” An internationally renowned investigator, Melvin has made landmark contributions to the field of salivary gland physiology.
To help inform future health policy decisions, NIDCR is working toward collecting evidence of the biological effects of electronic cigarettes. With the release of two funding opportunities, NIDCR will support research aimed at the possible effects on the oral cavity of aerosol mixtures produced by electronic cigarettes. Applications for R01 and R21 research funding opportunities are due on July 28.
On May 15, the health effects of electronic cigarettes was the topic of the NIDCR Clinical Research Fellowship Grand Rounds, which was held on the NIH campus. Stanton Glantz, PhD, professor of medicine at the University of California, San Francisco (UCSF) School of Medicine, presented a lecture called “E-cigarettes: Back to the Future.” Dr. Glantz is the director of the UCSF Center for Tobacco Control Research and Education and the principal investigator in the UCSF Tobacco Center of Regulatory Science.
In May, the University of Florida College of Veterinary Medicine selected Lauren P. Davidson, DVM, MS, DACLAM, NIDCR animal program director, as the recipient of the 2015 Distinguished Service Award. Each year, the College of Veterinary Medicine recognizes outstanding alumni with awards in several categories of distinction, and Dr. Davidson, who is a Commander in the U.S. Public Health Service (PHS), received the Distinguished Service Award for her public service achievements, including participation in PHS readiness response activities and mentoring students.
Applications are due on July 1 for the position of assistant clinical investigator in NIDCR’s Oral and Pharyngeal Cancer Branch in DIR. Applicants must have a PhD and DDS/DMD and a license that permits practice of dentistry at the NIH Clinical Center. In addition, applicants must have an in-depth knowledge of basic immunology and infectious diseases of the oral cavity, training and research experience in oral pathology and oral manifestations of immunologic/inflammatory diseases, with a particular emphasis on graft-versus-host disease.
You can learn about current NIDCR job opportunities by looking at the Job Openings section of NIDCR’s website and by following us on Twitter and LinkedIn.
The next meeting of the National Advisory Dental and Craniofacial Research Council will be on September 18, 2015, on the NIH campus in Bethesda, Md. The public may attend in person in conference room 10, which is on the 6th floor of the C wing in Building 31, or view the meeting remotely via NIH videocast.
NIH has formed a Working Group of the Advisory Committee to the NIH Director with expertise in precision medicine and large clinical research studies to guide the development and implementation of the President’s Precision Medicine Initiative. This Working Group is seeking public input through a series of workshops with patient, scientific, and other stakeholder groups to help design the initiative and to formulate a vision for building a national participant group of at least one million Americans.
All public workshops are videocast live and also archived. The next two workshops are shown below:
In September 2015, the team of experts will deliver a preliminary report to inform future efforts of the Precision Medicine Initiative.
On April 27, the Department of Health and Human Services (HHS) released the final Public Health Service recommendation for the optimal fluoride level in drinking water to prevent tooth decay. The new recommendation is for a single level of 0.7 milligram of fluoride per liter of water. This recommendation updates and replaces the previous recommended range, which was 0.7 to 1.2 milligrams per liter, issued in 1962.
HHS recommended the change in optimal fluoride concentration because Americans now have access to more sources of fluoride, such as toothpaste and mouth rinses, than they did when water fluoridation was first introduced in the United States. As a result, the prevalence of fluorosis has increased, which, in most cases, manifests as barely visible lacy white spots on the tooth enamel. The new recommended level will maintain the protective decay prevention benefits of water fluoridation and reduce the occurrence of dental fluorosis.
A federal panel reviewed the scientific evidence related to fluoride concentration in drinking water. Members of the federal panel included Isabel Garcia, DDS, MPH (then deputy director of NIDCR), Amit Chattopadhyay, BDS, MDS, MPH, PhD (then in NIDCR’s Office of Science Policy and Analysis (OSPA)), and Timothy Iafolla, DMD, MPH, in OSPA.
On July 1, Jack Whitescarver, PhD, who has led the Office of AIDS Research at NIH since 2000, will step down from his post. He also has served as NIH Associate Director for AIDS Research.
On April 1, Douglas Lowy, MD, was named acting director of the National Cancer Institute (NCI). Lowy has served as the deputy director of NCI since July 2010, helping lead key scientific initiatives.
On June 11, NIH announced that Walter J. Koroshetz, MD, was selected to be the director of the National Institute of Neurological Disorders and Stroke (NINDS). He has served as acting director of NINDS since October 2014.
On April 28, NIH announced that Eliseo J. Pérez-Stable, MD, will become director of the National Institute on Minority Health and Health Disparities. Currently, he is at the University of California, San Francisco, where he is a professor of medicine, chief of the Division of General Internal Medicine, and director of the Center for Aging in Diverse Communities. He is expected to join NIH in September.
In April, NIH launched a new site (https://datascience.nih.gov) for the biomedical data science community. One of the features is a calendar of NIH events of interest to the data science community. The Big Data to Knowledge (BD2K) section of the new site replaces the old BD2K site but is still accessible from http://bd2k.nih.gov.
On May 26 and 27, NIH hosted the 10th Annual NIH Pain Consortium Symposium on the NIH campus in Bethesda. The two-day event was called “Looking Back and to the Future.” The agenda, May 26 video, and May 27 video are available through the NIH Pain Consortium website.
Applications are due by August 27 for the Lasker Clinical Research Scholar Program. This program, which honors the contributions of Mary and Albert Lasker to the biomedical community, supports exceptional clinical researchers in the early stages of their careers to promote their development to fully independent positions. Lasker Scholars receive a unique combination of NIH funding for clinical research for up to 10 years.
In April, NIH announced that 55 talented and diverse students, representing 37 universities, were selected for the fourth class of the Medical Research Scholars Program (MRSP). Among the scholars in the 2015-2016 class is Tarek Metwally, a dental student at the University of Michigan School of Dentistry. The program places creative, research-oriented dental, medical, and veterinary students in NIH laboratories and clinics to conduct basic, clinical, or translational research in areas that match their career interests and research goals.
The NIH has established the NIH Language Access Plan, a comprehensive strategy being implemented across the agency – including at NIDCR -- to help people with limited English proficiency access NIH programs and activities. The Language Access Plan will help ensure that individuals, regardless of their language ability, can access important health information and participate in clinical trials.
The advancement of science requires rigor in designing and performing scientific research so that the biomedical research findings may be reproduced. In April, NIH launched a web portal (http://www.nih.gov/science/reproducibility/index.htm) as a resource for online video training modules, publications, and a calendar of meetings related to rigor and reproducibility.
Using molecular techniques and living tissue cultures from genetically modified mouse embryos, members of NIDCR's Matrix and Morphogenesis Section are the first to describe the cellular cross talk that promotes the innervation of salivary glands. These findings are an important advance toward the goal of regenerating or repairing salivary glands.
Record-setting $3.1M NIH Grant to Improve Dental Experience for Children with Autism University of Southern California
Regenerative Medicine in Dentistry: Making Strides Toward a “Bio-Tooth”Texas A&M University Baylor College of Dentistry
TGen Led Study Points Towards New Strategies for Stopping the Spread of Staph and MRSAThe Translational Genomics Research Institute
Viral History in a Drop of Blood: VirScan Reveals Current and Past Infections in a Single TestHarvard Medical School
What Are Medicare Costs for Patients with Oral Cavity, Pharyngeal Cancers?Pennsylvania State University
Oral Bacterium Possibly Associated with Systemic Disease Found in Alabama SchoolchildrenAmerican Society for Microbiology
UCLA Scientists Explain Mechanism That Makes Their Mouthwash So Effective Against Tooth DecayUniversity of California, Los Angeles
For Children with Autism, Trips to the Dentist Just Got EasierUniversity of Southern California
Evolution of Stem Cells Traced in Study of Fossilized Rodent TeethUniversity of California San Francisco
Telegram & Gazette: Shriver Center Projects Aim to Improve Dental Care for Those with DisabilitiesUniversity of Massachusetts Medical School
Stem Cells that Prevent Birth Defect Also Repair Facial InjuriesUniversity of Southern California
NYU Researchers Find Diabetes Perceptions Vary According to Risk FactorsNew York University
New Genomics Tool Could Help Predict Tumor Aggressiveness, Treatment OutcomesOhio State University
International Team of Researchers Led by UC Davis Receives $4 million NIH Grant to Study Skull Disorder in Infants UC Davis
UMKC Research Results in Cancer Patients’ Dental Care ProtocolsUniversity of Missouri-Kansas City
For Most Children with HIV and Low Immune Cell Count, Cells Rebound After TreatmentNIH
Ostrow researcher Yang Chai’s Scientific Discovery Could Lead to Effective Biological Treatment for a Common Birth DefectOstrow School of Dentistry
UMMS Working to Improve Oral Health for People with Intellectual DisabilitiesUniversity of Massachusetts Medical School
Grant to Boost Head and Neck Lymphedema ResearchVanderbilt University
Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01)
Administrative Supplements for Tobacco Regulatory Research on Tobacco Flavors and Flavorings (Admin Supp)
Immune System Plasticity in the Pathogenesis and Treatment of Complex Dental, Oral, and Craniofacial Diseases (R01)
Immune System Plasticity in the Pathogenesis and Treatment of Complex Dental, Oral, and Craniofacial Diseases (R21)
Administrative Supplements for Research on Dietary Supplements (Admin Supp)
NLM Administrative Supplements for Informationist Services in NIH-funded Research Projects (Admin Supp)
Discovery of the Genetic Basis of Structural Birth Defects and of Childhood Cancers: Gabriella Miller Kids First Pediatric Research Program (X01)
Limited Competition: National Primate Research Centers (P51)
The Health of Sexual and Gender Minority (SGM) Populations (R01)
The Health of Sexual and Gender Minority (SGM) Populations (R03)
The Health of Sexual and Gender Minority (SGM) Populations (R15)
The Health of Sexual and Gender Minority (SGM) Populations (R21)
PHS 2015-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])
PHS 2015-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])
Oral Immune System Plasticity in Chronic HIV Infection Under Treatment and Oral Co-Infections (R01)
Lifespan Human Connectome Project: Baby Connectome (U01)
Neuroimaging Informatics Tools and Resources Clearinghouse (U24)
NIH Transformative Research Awards (R01)
Novel or Enhanced Dental Restorative Materials for Class V Lesions (R01)
Links to NIH Notices are available in the Grants and Funding section of NIDCR’s website.