NIDCR News

Agnes Binagwaho, MD 

Rwandan Health Minister Agnes Binagwaho, MD, to Deliver the 2015 Barmes Global Health Lecture

On July 29, Agnes Binagwaho, MD, Minister of Health of the Republic of Rwanda, will deliver the 2015 David E. Barmes Global Health Lecture on the NIH campus in Bethesda, Maryland. Her lecture is called "Medical Research and Capacity Building for Development: The Experience of Rwanda." NIDCR and the Fogarty International Center are cosponsoring the event. The David E. Barmes Global Health Lecture series honors the late David Edward Barmes, who was NIDCR’s special expert for international health. The lecture, which is free and open to the public, will be webcast live and archived.

Janice S. Lee, DDS, MD, MS 

Janice S. Lee, DDS, MD, MS, Appointed as NIDCR Intramural Clinical Director

In April, Janice S. Lee, DDS, MD, MS, was appointed as the clinical director of NIDCR’s Division of Intramural Research. Dr. Lee, a board-certified oral and maxillofacial surgeon, joined NIDCR as the deputy clinical director in August 2013, after a decade at the University of California, San Francisco. NIDCR Director Martha J. Somerman, DDS, PhD, said, “In the short time she has been intramural deputy clinical director, Dr. Lee has distinguished herself as an outstanding leader with a deep comprehension of the importance of basic research as well as the tireless dedication to translating preclinical research results into protocols for clinical studies.” Dr. Lee’s clinical and translational research program is exploring the natural history and genetic etiology of craniofacial anomalies and growth abnormalities.

James E. Melvin, DDS, PhD 

James E. Melvin, DDS, PhD, Becomes NIDCR Deputy Scientific Director

In April, James E. Melvin, DDS, PhD, became the new deputy scientific director in the Division of Intramural Research. Dr. Melvin joined NIDCR in 2010 as the clinical director. “Dr. Melvin’s outstanding leadership during his five-year tenure has made a difference in the lives of the patients who visit our dental clinic, and in the lives and careers of the clinical fellows who are trained and mentored here,” said Dr. Somerman. “We are extremely fortunate to have a leader with Dr. Melvin’s versatility to transition from the administration of our clinical research to our basic research program.” An internationally renowned investigator, Melvin has made landmark contributions to the field of salivary gland physiology.

Electronic Cigarette 

NIDCR Joins New Area of Biomedical Research: Electronic Cigarette Health Effects

To help inform future health policy decisions, NIDCR is working toward collecting evidence of the biological effects of electronic cigarettes. With the release of two funding opportunities, NIDCR will support research aimed at the possible effects on the oral cavity of aerosol mixtures produced by electronic cigarettes. Applications for R01 and R21 research funding opportunities are due on July 28.

On May 15, the health effects of electronic cigarettes was the topic of the NIDCR Clinical Research Fellowship Grand Rounds, which was held on the NIH campus. Stanton Glantz, PhD, professor of medicine at the University of California, San Francisco (UCSF) School of Medicine, presented a lecture called “E-cigarettes: Back to the Future.” Dr. Glantz is the director of the UCSF Center for Tobacco Control Research and Education and the principal investigator in the UCSF Tobacco Center of Regulatory Science.

Lauren P. Davidson 

NIDCR Animal Program Director Lauren P. Davidson, DVM, MS, Receives Distinguished Service Award  

In May, the University of Florida College of Veterinary Medicine selected Lauren P. Davidson, DVM, MS, DACLAM, NIDCR animal program director, as the recipient of the 2015 Distinguished Service Award. Each year, the College of Veterinary Medicine recognizes outstanding alumni with awards in several categories of distinction, and Dr. Davidson, who is a Commander in the U.S. Public Health Service (PHS), received the Distinguished Service Award for her public service achievements, including participation in PHS readiness response activities and mentoring students.​

Clinical Investigator building 

Applications for Assistant Clinical Investigator Due July 1

Applications are due on July 1 for the position of assistant clinical investigator in NIDCR’s Oral and Pharyngeal Cancer Branch in DIR. Applicants must have a PhD and DDS/DMD and a license that permits practice of dentistry at the NIH Clinical Center. In addition, applicants must have an in-depth knowledge of basic immunology and infectious diseases of the oral cavity, training and research experience in oral pathology and oral manifestations of immunologic/inflammatory diseases, with a particular emphasis on graft-versus-host disease.

You can learn about current NIDCR job opportunities by looking at the Job Openings section of NIDCR’s website and by following us on Twitter and LinkedIn. ​


September NIDCR Advisory Council Meeting

The next meeting of the National Advisory Dental and Craniofacial Research Council will be on September 18, 2015, on the NIH campus in Bethesda, Md. The public may attend in person in conference room 10, which is on the 6th floor of the C wing in Building 31, or view the meeting remotely via NIH videocast

NIH/HHS News

A group of people standing 

NIH Advances the President’s Precision Medicine Initiative

NIH has formed a Working Group of the Advisory Committee to the NIH Director with expertise in precision medicine and large clinical research studies to guide the development and implementation of the President’s Precision Medicine Initiative. This Working Group is seeking public input through a series of workshops with patient, scientific, and other stakeholder groups to help design the initiative and to formulate a vision for building a national participant group of at least one million Americans.

All public workshops are videocast live and also archived. The next two workshops are shown below:

In September 2015, the team of experts will deliver a preliminary report to inform future efforts of the Precision Medicine Initiative.

HHS Releases Final Recommendation for Fluoride Concentration in Drinking Water

On April 27, the Department of Health and Human Services (HHS) released the final Public Health Service recommendation for the optimal fluoride level in drinking water to prevent tooth decay. The new recommendation is for a single level of 0.7 milligram of fluoride per liter of water. This recommendation updates and replaces the previous recommended range, which was 0.7 to 1.2 milligrams per liter, issued in 1962.

HHS recommended the change in optimal fluoride concentration because Americans now have access to more sources of fluoride, such as toothpaste and mouth rinses, than they did when water fluoridation was first introduced in the United States. As a result, the prevalence of fluorosis has increased, which, in most cases, manifests as barely visible lacy white spots on the tooth enamel. The new recommended level will maintain the protective decay prevention benefits of water fluoridation and reduce the occurrence of dental fluorosis.

A federal panel reviewed the scientific evidence related to fluoride concentration in drinking water. Members of the federal panel included Isabel Garcia, DDS, MPH (then deputy director of NIDCR), Amit Chattopadhyay, BDS, MDS, MPH, PhD (then in NIDCR’s Office of Science Policy and Analysis (OSPA)), and Timothy Iafolla, DMD, MPH, in OSPA. 

Jack Whitescarver, PhD 

Jack Whitescarver, PhD, Steps Down as Director of NIH’s Office of AIDS Research

On July 1, Jack Whitescarver, PhD, who has led the Office of AIDS Research at NIH since 2000, will step down from his post. He also has served as NIH Associate Director for AIDS Research.

Douglas Lowy, MD 

Douglas Lowy, MD, Is Acting Director of the National Cancer Institute

On April 1, Douglas Lowy, MD, was named acting director of the National Cancer Institute (NCI). Lowy has served as the deputy director of NCI since July 2010, helping lead key scientific initiatives.

Walter J. Koroshetz, MD 

NIH Names Walter J. Koroshetz, MD, Director of the National Institute of Neurological Disorders and Stroke

On June 11, NIH announced that Walter J. Koroshetz, MD, was selected to be the director of the National Institute of Neurological Disorders and Stroke (NINDS). He has served as acting director of NINDS since October 2014.

Dr. Eliseo Pérez-Stable 

Dr. Eliseo Pérez-Stable Will Become Director of the National Institute on Minority Health and Health Disparities

On April 28, NIH announced that Eliseo J. Pérez-Stable, MD, will become director of the National Institute on Minority Health and Health Disparities. Currently, he is at the University of California, San Francisco, where he is a professor of medicine, chief of the Division of General Internal Medicine, and director of the Center for Aging in Diverse Communities. He is expected to join NIH in September.

Data Science web site 

NIH Launches New Data Science Website

In April, NIH launched a new site (https://datascience.nih.gov) for the biomedical data science community. One of the features is a calendar of NIH events of interest to the data science community. The Big Data to Knowledge (BD2K) section of the new site replaces the old BD2K site but is still accessible from http://bd2k.nih.gov.

A woman looking at a computer screen 

Videos Available for 10th Annual NIH Pain Consortium Symposium

On May 26 and 27, NIH hosted the 10th Annual NIH Pain Consortium Symposium on the NIH campus in Bethesda. The two-day event was called “Looking Back and to the Future.” The agenda, May 26 video, and May 27 video are available through the NIH Pain Consortium website.

A man looking at a document 

August 27 Deadline for Lasker Clinical Research Scholar Program

Applications are due by August 27 for the Lasker Clinical Research Scholar Program. This program, which honors the contributions of Mary and Albert Lasker to the biomedical community, supports exceptional clinical researchers in the early stages of their careers to promote their development to fully independent positions. Lasker Scholars receive a unique combination of NIH funding for clinical research for up to 10 years.

Dental Student Is Part of 2015-2016 Class of NIH Medical Scholars

In April, NIH announced that 55 talented and diverse students, representing 37 universities, were selected for the fourth class of the Medical Research Scholars Program (MRSP). Among the scholars in the 2015-2016 class is Tarek Metwally, a dental student at the University of Michigan School of Dentistry. The program places creative, research-oriented dental, medical, and veterinary students in NIH laboratories and clinics to conduct basic, clinical, or translational research in areas that match their career interests and research goals.

A white man showing a black girl a book 

NIH Establishes Language Access Plan to Reduce Language Barriers

The NIH has established the NIH Language Access Plan, a comprehensive strategy being implemented across the agency – including at NIDCR -- to help people with limited English proficiency access NIH programs and activities. The Language Access Plan will help ensure that individuals, regardless of their language ability, can access important health information and participate in clinical trials.

NIH Promotes Rigor and Reproducibility in Research

The advancement of science requires rigor in designing and performing scientific research so that the biomedical research findings may be reproduced. In April, NIH launched a web portal (http://www.nih.gov/science/reproducibility/index.htm) as a resource for online video training modules, publications, and a calendar of meetings related to rigor and reproducibility.

Science Advances

A group of scientists 

Spying on Cellular Cross Talk

Using molecular techniques and living tissue cultures from genetically modified mouse embryos, members of NIDCR's Matrix and Morphogenesis Section are the first to describe the cellular cross talk that promotes the innervation of salivary glands. These findings are an important advance toward the goal of regenerating or repairing salivary glands.

Research News from NIDCR Grantees

June

Record-setting $3.1M NIH Grant to Improve Dental Experience for Children with Autism
University of Southern California

Regenerative Medicine in Dentistry: Making Strides Toward a “Bio-Tooth”​
Texas A&M University Baylor College of Dentistry​

TGen Led Study Points Towards New Strategies for Stopping the Spread of Staph and MRSA
The Translational Genomics Research Institute

Viral History in a Drop of Blood: VirScan Reveals Current and Past Infections in a Single Test
Harvard Medical School

What Are Medicare Costs for Patients with Oral Cavity, Pharyngeal Cancers?​
Pennsylvania State University​

Oral Bacterium Possibly Associated with Systemic Disease Found in Alabama Schoolchildren
American Society for Microbiology

UCLA Scientists Explain Mechanism That Makes Their Mouthwash So Effective Against Tooth Decay​
University of California, Los Angeles

May

For Children with Autism, Trips to the Dentist Just Got Easier
University of Southern California

April

Evolution of Stem Cells Traced in Study of Fossilized Rodent Teeth
University of California San Francisco

Telegram & Gazette: Shriver Center Projects Aim to Improve Dental Care for Those with Disabilities
University of Massachusetts Medical School

Stem Cells that Prevent Birth Defect Also Repair Facial Injuries
University of Southern California​

NYU Researchers Find Diabetes Perceptions Vary According to Risk Factors
New York University

New Genomics Tool Could Help Predict Tumor Aggressiveness, Treatment Outcomes
Ohio State University

March

International Team of Researchers Led by UC Davis Receives $4 million NIH Grant to Study Skull Disorder in Infants external link
UC Davis

UMKC Research Results in Cancer Patients’ Dental Care Protocols
University of Missouri-Kansas City

For Most Children with HIV and Low Immune Cell Count, Cells Rebound After Treatment
NIH

Ostrow researcher Yang Chai’s Scientific Discovery Could Lead to Effective Biological Treatment for a Common Birth Defect
Ostrow School of Dentistry

UMMS Working to Improve Oral Health for People with Intellectual Disabilities
University of Massachusetts Medical School

Grant to Boost Head and Neck Lymphedema Research
Vanderbilt University

 

Funding Opportunities

Program Announcements

Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01)    

Administrative Supplements for Tobacco Regulatory Research on Tobacco Flavors and Flavorings (Admin Supp)

Immune System Plasticity in the Pathogenesis and Treatment of Complex Dental, Oral, and Craniofacial Diseases (R01)

Immune System Plasticity in the Pathogenesis and Treatment of Complex Dental, Oral, and Craniofacial Diseases (R21)

Administrative Supplements for Research on Dietary Supplements (Admin Supp)  

NLM Administrative Supplements for Informationist Services in NIH-funded Research Projects (Admin Supp)

Discovery of the Genetic Basis of Structural Birth Defects and of Childhood Cancers: Gabriella Miller Kids First Pediatric Research Program (X01)​   

Limited Competition: National Primate Research Centers (P51) 

The Health of Sexual and Gender Minority (SGM) Populations (R01)

The Health of Sexual and Gender Minority (SGM) Populations (R03)

The Health of Sexual and Gender Minority (SGM) Populations (R15)

The Health of Sexual and Gender Minority (SGM) Populations (R21)

PHS 2015-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42])

PHS 2015-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])​

Requests for Applications

Oral Immune System Plasticity in Chronic HIV Infection Under Treatment and Oral Co-Infections (R01)

Lifespan Human Connectome Project: Baby Connectome (U01)

Neuroimaging Informatics Tools and Resources Clearinghouse (U24)

NIH Transformative Research Awards (R01)

Novel or Enhanced Dental Restorative Materials for Class V Lesions (R01)

Notices

Links to NIH Notices are available in the Grants and Funding section of NIDCR’s website.

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