News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: April 1, 2014

In this Issue:


NIDCR News

NIDCR Sponsors Symposia, Workshops, and Talks During Annual AADR Meeting
AADR meeting logoNIDCR sponsored a number of workshops, meetings, and presentations during the annual meeting of the American Association for Dental Research (AADR), held March 19-22 in Charlotte, NC. Included among these were a featured symposium on "Salivary Gland Organ Dynamics: From Development to Regeneration," an NIDCR trainees’ poster session, an NIDCR training directors’ meeting, presentations on NIDCR research training and career development opportunities, a presentation on "Enhancing Scientific Workforce Diversity," an NIDCR peer review presentation to new investigators and trainees, a presentation on “Conducting Clinical Research," and the Distinguished Lecture Series on "Stem Cells in Tissue Engineering and Regenerative Medicine."  Meeting participants also visited the NIDCR information and consultation booth. 

FY 2014 Funding Plan
See NIDCR's FY 2014 Funding Plan:
http://go.usa.gov/KwVW

FY 2015 Congressional Justification
See the NIDCR FY 2015 Congressional Justification:
http://officeofbudget.od.nih.gov/pdfs/FY15/NIDCR%20FY%202015%20CJ%20-%20Final.pdf

Job Opening: Director, Division of Extramural Research
NIDCR is seeking applicants for the position of Director, Division of Extramural Research.  The DER Director oversees and manages an extramural research program portfolio of approximately $300 million and a staff of 28 health scientist administrators and other science professionals. The Program comprises four branches that encompass a full spectrum of basic, clinical, translational and population-based research: 1) Integrative Biology and Infectious Diseases Research Branch; 2) Translational Genomics Research Branch; 3) Behavioral and Social Sciences Research Branch; and 4) Center for Clinical Research.  Additional details about the position are found at:
http://go.usa.gov/KwyP
Review of applications will begin on April 30, 2014.  Applications received after this date may be considered until the position is filled.


 

NIH News

NIH Opens Research Hospital to Outside Scientists
NIH has announced 10 projects that will enable non-government researchers to conduct clinical research at the NIH's Clinical Center. Through these three-year, renewable awards of up to $500,000 per year, extramural researchers from academia and industry will collaborate with government scientists and have direct access to the broad resources of the NIH Clinical Center. The Clinical Center is the largest hospital in the nation devoted entirely to clinical research. 

The awards will support projects on a variety of diseases and health conditions that affect children and adults in the U.S. and worldwide. They include: a clinical trial for a new drug treatment for Nieman Pick C, a rare, fatal disease that is caused by the loss of ability to break down cholesterol and other fats; a clinical trial of a new drug treatment to prevent relapse in a form of childhood leukemia; a clinical trial of the genetic makeup of certain types of prostate cancer to gain insights that could yield new information for prevention and treatment efforts; development of a new catheter that can be threaded into the heart to relay high quality images needed for making surgical and treatment decisions; a long term follow-up study of patients treated for Cryptococcus gattii, an airborne fungus that can cause severe, sometimes fatal, respiratory infections; and a clinical trial of a new vaccine to prevent malaria.  See additional details:
http://www.nih.gov/news/health/mar2014/nichd-13.htm

New Accelerating Medicines Partnership
Accelerating Medical Partnerships logoThe Accelerating Medicines Partnership (AMP) is a bold new venture between the NIH, 10 biopharmaceutical companies, and several nonprofit organizations to transform the current model for developing new diagnostics and treatments by jointly validating promising biological targets of disease. The ultimate goal is to increase the number of new diagnostics and therapies for patients and reduce the time and cost of developing them. Through the Foundation for the NIH (FNIH), AMP partners will invest more than $230 million over five years in the first projects, which focus on Alzheimer's disease, type 2 diabetes, and rheumatoid arthritis and systemic lupus erythematosus (lupus). A critical component of the partnership is that industry partners have agreed to make the AMP data and analyses publicly accessible to the broad biomedical community. These pilot projects will set the stage for broadening AMP to other diseases and conditions.  Additional details about the new partnership are found at:
http://www.nih.gov/science/amp/index.htm

NIH Releases Comprehensive New Data Outlining Hispanic/Latino Health and Habits
Cover of Hispanic Community Health Study Data Book A comprehensive health and lifestyle analysis of people from a range of Hispanic/ Latino origins shows that this segment of the U.S. population is diverse, not only in ancestry, culture, and economic status, but also in the prevalence of several diseases, risk factors, and lifestyle habits. The health data are derived from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a landmark study that enrolled about 16,415 Hispanic/Latino adults living in San Diego, Chicago, Miami, and the Bronx, N.Y., who self-identified with Central American, Cuban, Dominican, Mexican, Puerto Rican, or South American origins. These new findings have been compiled and published as the Hispanic Community Health Study Data Book: A Report to the Communities.  The numerous findings described by the HCHS/SOL researchers confirmed some existing knowledge while also uncovering some new health trends. See the full HCHS/SOL Data Book: A Report to the Communities:
http://www.nhlbi.nih.gov/resources/obesity/pop-studies/hchs.htm

NIH Adds Substantial Set of Genetic, Health Information dbGap logo  to Online Database
Researchers will now have access to genetic data linked to medical information on a diverse group of more than 78,000 people, enabling investigations into many diseases and conditions. The data, from one of the nation’s largest and most diverse genomics projects — Genetic Epidemiology Research on Aging (GERA) — have just been made available to qualified researchers through the database of Genotypes and Phenotypes (dbGaP), an NIH online genetics database. 

The GERA cohort — average age 63 — was developed collaboratively by Kaiser Permanente and the University of California, San Francisco (UCSF). The cohort is part of the Research Program on Genes, Environment, and Health (RPGEH), which includes more than 430,000 adult members of the Kaiser Permanente Northern California system. Data from this larger cohort include electronic medical records, behavioral and demographic information from surveys, and saliva samples from 200,000 participants obtained with informed consent for genomic and other analyses. 

Investigators who are interested in applying for access to this database should follow the procedures on the dbGaP website. Specific information on the data can be found at http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000674.v1.p1 

His Holiness the Dalai Lama Speaks at NIH
His Holiness the Dalai LamaOn Friday, March 7th, His Holiness the Dalai Lama spoke at NIH about "The Role of Science in Human Flourishing."  He praised scientists, in particular for their openmindedness and what he described as a healthy skepticism about evidence and hyperbole.  He also emphasized the capacity of scientists from around the world to work together and ignore differences in geography, race, ethnicity, gender, religion, and social class. The Dalai Lama noted these traits set scientists apart and provide an international, professional role model.  He also went on to discuss emotional inner peace and the impact of maternal affection in the life long health of children. Watch the videocast of the Dalai Lama:
http://videocast.nih.gov/summary.asp?live=13812&bhcp=1 

Dr. Yvonne Maddox Named Acting Director, National Institute on Minority Health and HYvonne T. Maddox, Ph.D.ealth Disparities
Yvonne T. Maddox, Ph.D., has been named Acting Director of the National Institute on Minority Health and Health Disparities (NIMHD). She replaces Dr. John Ruffin, former NIMHD Director, who retired at the end of March.

Dr. Maddox has a long history of leadership with the NIH, including serving as the Deputy Director of the Eunice Kennedy Shriver National Institute of Child Health and Human Development since 1995 and as Acting Deputy Director of the NIH from 2000 - 2002. She also leads several committees to advance medical research for affected communities to improve their health. Among her many committee memberships, she has served as Executive Director of the HHS Cancer Health Disparities Progress Review Group, and co-chaired the HHS Initiative to Reduce Infant Mortality in Minority Communities.  In addition, she co-chaired the first NIH Strategic Plan to “Reduce and Ultimately Eliminate Health Disparities.”


SCIENCE ADVANCES


One Way or Another
Formation of tooth-like structures in the dentin matrixWhy do two proteins cleaved from the same source appear at disproportionate levels in the dentin matrix?  Researchers offer a possible explanation:
http://go.usa.gov/KwVd









Knitting A Broken Bone
BiglycanNIDCR researchers show that biglycan plays a role in healing bone fractures:
http://go.usa.gov/KwmV








Controlling Cancer Growth
Fluorescent collagen internalized into the skin cells of a mouseNIDCR scientists may be first to show that p38 is highly active in head and neck cancers:
http://go.usa.gov/Kwmh








TMD: First Evidence-Based Diagnostic Criteria
profile of face with star indicating temporomandibular joint location
Researchers have developed the first evidence-based diagnostic criteria to better diagnose temporomandibular disorders (TMD), more commonly known as TMJ:
http://go.usa.gov/Kwyk







FUNDING OPPORTUNITY NEWS

PROGRAM ANNOUNCEMENTS

Behavioral/Social Science Research
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Establishing Behavioral and Social Measures for Causal Pathway Research in Dental, Oral and Craniofacial Health (R21) 3/05/14 PAR-14-144 Melissa Riddle
301-451-3888
9/17/17
Establishing Behavioral and Social Measures for Causal Pathway Research in Dental, Oral and Craniofacial Health (R01)  3/05/17 PAR-14-143 Melissa Riddle
301-451-3888
9/17/17
Computational Science
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science (R43/R44) 3/14/14 PA-14-154 Steven Scholnick
301-594-3977
5/08/17
Early Stage Development of Technologies in Biomedical Computing, Informatics, and Big Data Science (R01) 314/17 PA-14-155 Steven Scholnick
301-594-3977
5/08/17
Fellowships
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral MD/PhD or Other Dual Doctoral Degree Fellows (Parent F30)  3/07/14 PA-14-150 Leslie Frieden
301-496-4263
1/08/17
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) 3/07/14 PA-14-147 Leslie Frieden
301-496-4263
1/08/17
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31 - Diversity)  3/07/14 PA-14-148 Leslie Frieden
301-496-4263
1/08/17
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) 3/07/14 PA-14-149 Leslie Frieden
301-496-4263
1/08/17
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Senior Fellowship (Parent F33)  3/07/14 PA-14-151 Leslie Frieden
301-496-4263
1/08/17
Small Business
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Direct Phase II SBIR Grants to Support Biomedical Technology Development 2/05/14 PAR-14-088

R. Dwayne  Lunsford
301-594-2421

1/08/17
NOTICES
Title NIH
Guide
Notice Number
Notice of Extension of Eligibility for PA-14-150 "Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral MD/PhD or Other Dual-Doctoral Degree Fellowship (Parent F30)"  3/20/14 NOT-OD-14-072
NIH Policy for Managing Conflict of Interest in the Peer Review of Concepts and Proposals for Research and Development Contract Projects 3/20/14/ NOT-OD-14-069
NIH Extramural Grant Systems Upgrade for Unicode Compatibility Means Memorial Day Weekend Downtime  3/14/14 NOT-OD-14-071
Adjustments to May 25-28, 2014 Grant Application Due Dates  3/14/14 NOT-OD-14-070
Notice of Reissuance of Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship Funding Opportunity Announcements  3/07/14 NOT-OD-14-066
Notice to Extend the Due Date and Expiration Date for RFA-MH-14-217 "BRAIN Initiative: Planning for Next Generation Human Brain Imaging (R24)" 3/05/14 NOT-MH-14-010
Notice of Online Data Submission and Access to the National Institutes of Health (NIH) database of Genotypes and Phenotypes (dbGaP) 3/05/14 NOT-OD-14-065
NIH Will Open the Research Performance Progress Report (RPPR) for All Type 5 Non-SNAP Progress Reports on April 25, 2014  3/04/14 NOT-OD-14-064
Registration Now Open for the 2014 NIH Regional Seminar on Program Funding and Grants Administration in Baltimore, MD 2/20/14 NOT-OD-14-061
Notice of Intent to Publish the Reissuance of the "Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships to Promote Diversity in Health-Related Research (Parent F31- Diversity)" Funding Opportunity Announcement 2/18/14 NOT-OD-14-060
Notice of Intent to Publish the Reissuance of the "Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (Parent F33)" Funding Opportunity Announcement  2/18/14 NOT-OD-14-059
Notice of Intent to Publish the Reissuance of the "Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (Parent F32)" Funding Opportunity Announcement 2/18/14 NOT-OD-14-058
Notice of Intent to Publish the Reissuance of the "Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (Parent F31)" Funding Opportunity Announcement 2/18/14 NOT-OD-14-057
Notice of Intent to Publish the Reissuance of the "Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (Parent F30)" Funding Opportunity Announcement 2/18/14 NOT-OD-14-056
Notice of Correction to Award Information, Eligibility Information, and Application and Submission Information in RFA-RM-13-016, "NIH Building Infrastructure Leading to Diversity (BUILD) Initiative (U54)" 2/11/14 NOT-RM-14-008
NIH Fiscal Policy for Grant Awards - FY 2014  2/10/14 NOT-OD-14-055
Ruth L. Kirschstein National Research Service Award (NRSA) Stipends, Tuition/Fees and Other Budgetary Levels Effective for Fiscal Year 2014    2/10/14 NOT-OD-14-046
Notice of Revised Term of Award for All Recovery Act Awards to Repeal Section 1512 Reporting Requirement Effective February 1, 2014 2/07/14 NOT-OD-14-054
Timetable for Next Round Resubmission of New Investigator R01 Applications Changed for October 2014 Council 2/06/14 NOT-OD-14-050
NIH Implements Option for Applicants to Switch between the SBIR/STTR programs and the SBIR Direct to Phase II pilot of the SBIR/STTR Reauthorization Act of 2011  2/05/14 NOT-OD-14-048

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Thank you.


National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

National Institute of Dental and Craniofacial Research   National Institutes of Health (NIH)   Department of Health and Human Services (HHS)   USA.gov