Skip to main content
U.S. flag

An official website of the United States government

Here’s how you know

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

HTTPS

Secure .gov websites use HTTPS
A lock (LockA locked padlock) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Español
NIH National Institute of Dental and Craniofacial Research (NIDCR) Home page
  • Health Info
  • Research
  • Grants & Funding
  • Careers & Training
  • News & Events
  • About Us
  • Health Info
    • Publications
    • Clinical Trials
    • Data & Statistics
    • Finding Dental Care
  • Research
    • Research Conducted at NIDCR (Intramural)
    • Research Funded by NIDCR (Extramural)
    • Human Subjects Research
    • Clinical Trials
    • Data & Statistics
    • Scientific Data Sharing
    • Research Priorities
    • Research Investments & Advances
    • Oral Health in America Report
    • COVID-19
  • Grants & Funding
    • Notices of Funding Opportunities
    • Grant Programs and Contacts
    • Funding Priorities
    • Funded Research
    • Human Subjects Research
    • Scientific Data Sharing
  • Careers & Training
    • Research Training at NIDCR (Intramural Opportunities)
    • Funding for Research Training (Extramural Opportunities)
    • Job Openings
    • Loan Repayment
    • Staff Contacts
  • News & Events
    • NIDCR News
    • Newsletter
    • Grantee News
    • Events
    • Images
    • For Reporters
  • About Us
    • Leadership & Staff
    • Advisory Committees
    • Strategic Plan
    • Oral Health in America Report
    • Congressional & Budget
    • Job Openings
    • Getting to NIDCR
    • Contact Us
    • Mission

Breadcrumb

  1. Home
  2. Health Info
Health Info
  • Publications
  • Clinical Trials
  • Data & Statistics
  • Finding Dental Care

Cancer Treatments & Oral Health

On this page

  1. Overview
  2. Causes
  3. Symptoms
  4. Treatment
  5. Helpful Tips
  6. Additional Resources
  7. Cancer Treatments & Oral Health Research from NIDCR
Back to top

Overview

Most people are aware of common side effects of cancer treatment like nausea and hair loss. But many don't realize that most people treated for cancer develop problems in the mouth. These problems can make it hard to eat, talk, and swallow. This may interfere with cancer treatment and lessen quality of life. This information will explain how you can prevent or manage these side effects.

Back to top

Causes

Head and neck radiation and chemotherapy can cause mouth problems that range from dry mouth to life-threatening infections. These problems can occur when receiving treatment or even months or years after treatment.

For example, mouth sores can occur because chemotherapy and radiation kill fast-growing cells including both cancer cells and healthy cells that are fast-growing, like the cells that line your mouth. In addition, radiation to the head and neck can damage the glands that make saliva (the salivary glands), greatly reducing the amount of saliva that’s produced. Without enough saliva, tooth decay and other infections can develop.

Back to top

Symptoms

Head and neck radiation may cause:

  • Dry mouth.
  • Severe tooth decay.
  • Loss of taste or changes in the way food tastes.
  • Sore mouth and gums.
  • Infections.
  • Jaw stiffness.
  • Limited mouth opening.
  • Jawbone changes.

Chemotherapy may cause:

  • Dry mouth.
  • Painful mouth and gums.
  • Oral bleeding.
  • Change in taste.
  • Burning, peeling, or swollen tongue.
  • Infection.
  • Mouth ulcers.
Back to top

Treatment

Treatment for oral side effects of cancer treatment will depend on which mouth problems you develop. For example, treatment for jaw stiffness or pain might consist of daily jaw exercises. Treatment for oral mucositis, which results in painful mouth sores, might require a medication to coat the lining of your mouth to protect it when you eat and/or a topical medication to numb the pain.

Be sure to follow all directions from your doctor or dentist about treating your mouth problems.

Back to top

Helpful Tips

If you are a cancer patient, here are some things you can do to reduce the risk and impact of treatment-related mouth problems:

  • See a dentist about 1 month before beginning cancer treatment to make sure your mouth is healthy.
  • Give your dentist your cancer doctor’s contact information. It’s important they talk to each other about your cancer treatment.
  • Take good care of your mouth during and after treatment. Follow the dentist’s instructions for how to keep your mouth clean.
  • Keep your mouth moist by drinking lots of water, sucking ice chips, and using sugar free gum or candy. Artificial saliva may also be necessary.
  • Avoid foods and drinks that could irritate your mouth such as sharp, crunchy foods or hot, spicy foods.
  • Avoid tobacco products and alcoholic beverages.
  • Call your healthcare provider if your mouth hurts.

If you receive radiation to the head and neck area, you should also:

  • Talk to your dentist about using fluoride gel to help prevent tooth decay.
  • Exercise the jaw muscles three times a day: open and close the mouth as far as possible (without causing pain) 20 times. This helps prevent jaw stiffness.
Back to top

Additional Resources

  • Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®) – Health Professional Version
    The NIH National Cancer Institute (NCI) provides information for health professionals about the oral complications caused by chemotherapy and head/neck radiation.
  • Oral Complications of Chemotherapy and Head/Neck Radiation (PDQ®) – Patient Version
    The NIH National Cancer Institute (NCI) has information for patients, families, and caregivers about the oral complications caused by chemotherapy and head/neck radiation.
  • MedlinePlus: Cancer Treatment and Oral Health
    The National Library of Medicine's collection of links to government, professional, and nonprofit/voluntary organizations with information on cancer treatment and oral health.
  • Support for People with Oral and Head and Neck Cancer, Inc.
    This organization offers patients, their families and friends, and the general community education about and support for oral, head, and neck cancers.
  • The Oral Cancer Foundation
    A foundation that raises awareness about oral and oropharyngeal cancer through education, research, and patient support.
Back to top

Cancer Treatments & Oral Health Research from NIDCR

  • The Many Long, Intrusive Arms of Cancer Cell Invasion
  • Turning the Tap Back On
  • Your Mouth on a Chip
  • Mimicking Mother Nature to Grow an Artificial Gland
  • A Four-Decade Quest to Uncover a Unique Molecule’s Secret
Back to top
Last Reviewed
October 2024
NIH
  • Home
  • Web Policies
  • Privacy
  • Contact Us
  • Freedom of Information Act
  • No Fear Act
  • Office of Inspector General
  • HHS Vulnerability Disclosure
  • Employee Intranet - Staff Only
Back to top