Building a Case for Biglycan
Interested in becoming an NIDCR post-doc? Here's another look inside an NIDCR lab and another glimpse at a budding research career.
A Unique Training Program
Dr. Jim Melvin talks about his vision for the Clinical Research Fellowship and the bright new look at the recently renovated NIDCR Dental Clinic.Welcome to the Academy
In February, three NIDCR grantees were elected to the American Academy of Engineering. Science Spotlight
plans over the coming weeks to interview all three scientists to hear their thoughts on receiving this high honor and learn more about the latest progress in tissue engineering. Our first stop is Gordana Vunjak-Novakovic, Ph.D. She is a professor of biomedical engineering and a professor of medicine at Columbia University in New York, where she serves as director of Columbia’s Laboratory for Stem Cells and Tissue Engineering and is the co-director of the Craniofacial Regeneration Center. Dr. Vunjak-Novakovic also is an associate director of NIH's Resource Center for Tissue Engineering. more.....
New Target for Periodontal Disease
In a paper published on March 25 in Nature Immunology
, a team of researchers reports on a potentially high-value new target in the fight against periodontal disease. The new lead is a glycoprotein called Del-1. NIDCR grantees and colleagues show for the first time in the gingiva that a breakdown in Del-1’s normal regulatory control of the immune-signaling protein IL-17 can drive the onset of periodontitis, particularly in aging. Based on this finding, the authors propose that periodontitis may be best characterized as a disruption of homeostasis, which then allows infectious and inflammatory conditions to proceed on their destructive paths. more......