News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: February 20, 2007

In this Issue:

1. NIDCR News  
2. NIH News
3. Funding Opportunities
4. Science Advances
5. NIDCR Personnel News

NIDCR NEWS

NIDCR Launches Pathway to Product Development Web Page
NIDCR has a new section on its website called " Pathway to Product Development" that highlights how to translate science into product development, the challenges involved in translational research, and the Institute’s SBIR/STTR offerings.  The site also provides advice on "10 Steps to Commercializing a Great Idea." 

FY 2008 NIDCR Congressional Justification Available
See the FY 2008 NIDCR Congressional Justification.

NIDCR Participates in High Priority Short-Term Project Award (R56)
A brief description of the High Priority Short-Term Project Award (R56) has been added to the Funding Mechanisms page on the NIDCR web site with links to the original NIH announcement and to the Notice announcing NIDCR participation.

NIDCR Support for Meetings and Scientific Conferences (R13/U13)
An updated description of the R13/U13 program has been added to the NIDCR web site that provides information about the types of meetings and conferences NIDCR will consider supporting.  It also directs potential applicants to consult with the appropriate program director before submitting a request for advance permission to submit an application. Finally, it provides the standardized form that is required for seeking this permission. 

NIH NEWS

News

R01 Grant Application Alert
New Process, New Forms
Required for Feb. 2007

New On-Line Training Resources Available for Electronic Grant Submission
Three new training resources have been added to the electronic submission training site.
The computer demos and presentations walk applicants through the process of finding grant opportunities and downloading applications, checking e-application status (for signing officials) and checking e-application status (for principal investigators).

Remember, R01 attachments must be in PDF format.   Information about this and other new requirements may be found in the  powerpoint presentation on Preparing for NIH Electronic Grant Applications.

President Signs NIH Reform Act

NIH Reform Act of 2006 - "This affirmation from Congress has come at a critical time, and we want to ensure that we take the best possible advantage of its promise. We will be communicating with the community regularly as we make progress in this process." - Elias A. Zerhouni, M.D.

On January 15, 2007, President Bush signed into law the NIH Reform Act following unanimous support by the Congress.  This action affirms the importance of NIH and its vital role in advancing biomedical research to improve the health of the Nation.  Provisions would revise Title IV of the PHS Act and create the Division of Program Coordination, Planning, and Strategic Initiatives, to be supported by the Common Fund.  The bill authorizes, but does not appropriate, for NIH $30,331,309,000 for FY 2007, $32,831,309,000 for FY 2008 and such sums as necessary for FY 2009. In addition, the bill:

  • calls for the establishment of a Scientific Management Review Board to review the structure of NIH every seven years
  • authorizes the NIH Director to award grants for demonstration projects for research bridging the biological sciences with the physical, chemical, mathematical, and computational sciences; and authorizes the establishment of demonstration programs that award grants, contracts, or engage in other transactions, for high-impact, cutting-edge research demonstration programs
  • deletes most reports pertaining to NIH in current law and replaces them with one biennial report to Congress

NIH Center for Scientific Review to Host Open House Workshops to Improve the Review of NIH Grant Applications
Starting in March 2007, the Center for Scientific Review (CSR) will convene the first of six one-day Open House Workshops in 2007 to solicit input from leaders of the scientific community and other stakeholders.  The input will be critical to realigning and reinventing CSR's application review groups so the $20+ billion NIH invests in biomedical research grants each year advances the most promising research.  Workshop participants also will provide input on other ongoing and proposed initiatives to improve CSR's peer review process.   See additional information, dates, and online registration forms for the CSR open house workshops.

Register for NIH Regional Seminars on Program Funding and Grants Administration
NIH is offering two regional seminars intended to help demystify the application and review process, clarify Federal regulations and policies, and highlight current areas of special interest or concern. The first seminar will be held March 5-7, 2007 in Salt Lake City, UT, and the second will take place April 24-26, 2007 in Research Triangle Park, NC. The seminars are appropriate for grants administrators, researchers new to NIH, and graduate students. 

NIH to Host SBIR/STTR Conference
On February 26-27, 2007, NIH will hold its 9th annual Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Conference in Las Vegas, NV.  The meeting will provide an overview of the SBIR/STTR programs with a focus on the process of moving an idea to product commercialization.     

Licensing Opportunities for Rare Disease Technologies Announced
On December 11, NIH launched a website offering technologies available for commercial licensing that are related to rare diseases or conditions .  The listing consists of more than 500 technologies, including drugs, biologics, and devices, available to be transferred from the NIH and the Food and Drug Administration to the private sector for further research and development and potential commercialization.  “By making it easier for pharmaceutical companies and academic institutions to identify licensing opportunities, this new site will help facilitate the transfer of research advances from bench to bedside where the interventions can ultimately benefit the patients,” said NIH Director Elias Zerhouni.

NIH in the Post-Doubling Era: Realities and Strategies
An article by NIH Director Elias A. Zerhouni, M.D., appeared in the November 17 issue of Science, entitled “ NIH Funding in the Post-Doubling Era: Realities and Strategies.” 

Seven New Members Appointed to Advisory Committee to the NIH Director
NIH has selected seven individuals to serve as members of the Advisory Committee to the Director (ACD).  The ACD advises the NIH Director on policy and planning issues.  The new members, who join 13 current members of the council, are Catherine D. DeAngelis, M.D., MPH, of Chicago, Illinois; Karen A. Holbrook, Ph.D., of Columbus, Ohio; Ralph I. Horwitz, M.D., of Stanford, California; Mary-Claire King, Ph.D., of Seattle, Washington; Alan, I. Leshner, Ph.D., of Washington, District of Columbia; John C. Nelson, M.D., MPH, FACOG, FACPM, of Chicago, Illinois; and Barbara L. Wolfe, Ph.D., of Seattle, Washington. 

Stephen E. Straus, M.D., Becomes Senior Advisor to NIH Director
On November 7, Dr. Stephen E. Straus, director of the National Center for Complementary and Alternative Medicine (NCCAM), stepped down from his leadership of the Center for health reasons.  Dr. Straus will become senior advisor to the NIH Director.  Dr. Zerhouni has named Ruth L. Kirschstein, M.D., formerly acting director of NIH, to be the acting director of NCCAM.

FUNDING ANNOUNCEMENTS  

PROGRAM ANNOUNCEMENTS

AIDS

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Research on Malignancies in AIDS and Acquired Immune Suppression (R01) 12/15/06 PA-07-173

Mostafa Nokta
301-594-7985

9/02/07

Behavioral/Social Science Research

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Oral Health of Special Needs and Older Populations (R01) 12/12/06 PA-07-151

Ruth Nowjack-Raymer
301-594-5394

1/03/10
Research on Mind-Body Interactions and Health (R01) 11/21/06 PA-07-046

Patricia Bryant
301-594-2095
Ruth Nowjack-Raymer
301-594-5394

1/03/10
Social and Cultural Dimensions of Health (R01) 11/21/06 PA-07-045

Patricia Bryant
301-594-2095
Ruth Nowjack-Raymer
301-594-5394

1/3/08

Biotechnology

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Application of Metabolomics for Translational and Biological Research (R21)  1/17/07 PA-07-302 Yasaman   Shirazi
301-594-4812
1/03/10
Application of Metabolomics for Translational and Biological Research (R01) 1/17/07 PA-07-301

Yasaman   Shirazi
301-594-4812

1/03/10
Bioengineering Research Grants (BRG) (R01) 1/08/07 PA-07-279 Eleni Kousvelari
301-594-2427
9/02/09
Nanoscience and Nanotechnology in Biology and Medicine (R01) 1/04/07 PAR-07-270

Eleni Kousvelari
301-594-2427

10/23/07
Nanoscience and Nanotechnology in Biology and Medicine (R21) 1/04/07 PAR-07-271

Eleni Kousvelari
301-594-2427

10/23/07

Cancer

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Protein Biomarkers of Infection-Associated Cancers (R01) 12/15/06 PA-07-179 Mostafa Nokta
301-594-7985
5/02/08

Career Development

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
NIH Pathway to Independence (PI) Award (K99/R00) 1/12/07 PA-07-297 Kevin Hardwick
301-594-2765
1/03/10

Clinical Research/Clinical Trials

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Clinical Studies of Bisphosphonate Therapy and Osteonecrosis of the Jaws (R01) 1/18/06 PA-07-185 Maria Teresa Canto
301-594-5497
11/06/09

Genetics and Developmental Biology

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Tools for Zebrafish Research (R01) 12/12/06 PAR-07-145 Rochelle Small
301-594-9898
9/20/07
Genetic and Genomic Analyses of Xenopus (R01) 12/12/06 PAR-07-144

Rochelle Small
301-594-9898

1/19/08

Health Disparities

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Community Participation in Research (R01) 1/08/07 PAR-07-283 Ruth Nowjack-Raymer
301-594-5394
5/18/07
Epidemiological and Behavioral Research in Oral Health (R01) 12/14/06 PA-07-169

Ruth Nowjack-Raymer
301-594-5394
Maria Teresa Canto
301-594-5497

1/03/10
Dissemination and Implementation Research in Health (R01) 11/22/06 PA-07-086

Patricia Bryant
301-594-2095
Ruth Nowjack-Raymer
301-594-5394

9/09/09

Immunology

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Immunology of Biofilms (R01)                                                1/09/07 PA-07-288 Sangeeta Bhargava
301-402-4243
7/02/09

Microbiology

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Novel Approaches to Study Polymicrobial Diseases (R01) 12/14/06 PA-07-171 Sangeeta Bhargava
301-402-4243
1/03/08
Metagenomic Analyses of the Oral Microbiome (R01) 12/14/06 PA-07-170

Sangeeta Bhargava
301-402-4243

1/03/08

Neurobiology/Pain

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Neurobiology of Migraine (R01)      1/18/07    PA-07-305        

John Kusiak
301-594-7984

11/06/09                
Neurobiology of Migraine (R21) 1/18/07 PA-07-306 John Kusiak
301-594-7984
11/17/09
Mechanisms, Models, Measurement, & Management in Pain Research (R01) 1/08/07 PA-07-282

John Kusiak
301-594-7984

9/02/09
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R03) 12/22/06 PA-07-263

John Kusiak
301-594-7984

11/17/07
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R21) 12/22/06 PA-07-264

John Kusiak
301-594-7984

11/17/07
Chronic Fatigue Syndrome: Pathophysiology and Treatment (R01) 11/06/07 PA-07-265

John Kusiak
301-594-7984

11/06/07
Temporomandibular Joint and Muscle Disorders: Pathophysiological Mechanisms Linking Comorbid Conditions (R01) 12/13/06 PA-07-150

John Kusiak
301-594-7984

3/02/09

NIH Roadmap-Related Initiatives

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Networks and Pathways Collaborative Research Projects (R01) 12/22/06 PA-07-266

Eleni Kousvelari
301-594-2427

9/02/09
Exploratory Collaborations with National Centers for Biomedical Computing (R01) 12/20/06 PAR-07-249

Eleni Kousvelari
301-594-2427

1/18/08
Exploratory Collaborations with National Centers for Biomedical Computing (R21) 12/21/06 PAR-07-250

Eleni Kousvelari
301-594-2427

1/18/08

Small Business

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
PHS 2007-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R41/R42])  1/16/07 PA-07-281 Mary Daley
301-594-4808
1/03/08
PHS 2007-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])  1/16/07 PA-07-280

Mary Daley
301-594-4808

1/03/08

Teeth and Bone

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Pharmacogenetics of Fluoride (R01) 12/07/06 PAR-07-131 Lillian Shum
301-594-0618
1/16/09
Pathophysiology of Bisphosphonates-Associated Osteonecrosis of the Jaw (R01) 12/07/06 PA-07-132

Lillian Shum
301-594-0618

7/02/09

Training

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (F33) 12/15/06 PA-07-172 Albert Avila
301-496-4263
12/09/09
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32) 12/12/06 PA-07-107

Albert Avila
301-496-4263

4/09/10
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships (F31) to Promote Diversity in Health-Related Research 12/12/06 PA-07-106

Albert Avila
301-496-4263

04/14/10


REQUESTS FOR APPLICATIONS

Neurobiology/Pain

Title NIH
Guide
PA
Number
NIDCR Contact Application Receipt Date
Neuroimaging Informatics Software Enhancement for Improved Interoperability and Dissemination (R03) 12/22/06 RFA-EB-07-002 John Kusiak
301-594-7984

2/22/07

Extension of National Research Service Award Training, Fellowship, and Career Development Funding Opportunity Announcements
The expiration date for several of the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional training grants (T), NRSA Fellowships (F), and Career Development (K) funding opportunity announcements has been extended until January 3, 2008.  See additional information about the affected NRSA awards.

SCIENCE ADVANCES

Scientists Discover How Maternal Smoking Can Cause Cleft Lip and Palate

Science News in Brief
Please see the following brief summaries of recent oral health research findings:

NIDCR PERSONNEL NEWS

Dr. Robert Fitzgerald Dies
It is with great sadness that we report the death of Dr. Robert J. Fitzgerald on January 18, 2007.  Dr. Fitzgerald was a research pharmacologist at the (then) NIDR from 1948-1969.  His landmark research, conducted together with Dr. Paul Keyes, demonstrated that specific bacteria cause dental caries.  He later extended this work to studies of other factors involved in the formation of tooth decay.  Dr. Fitzgerald served in the U.S. Public Health Service from 1945 to 1969, retiring with the rank of captain.  In 1969, he moved to Miami, FL and became chief of the Dental Research Unit at the Miami VA Medical Center and professor of microbiology at the University of Miami School of Medicine.  His group continued to make important observations relating to caries, periodontal disease, and root canal infections.  He was a member of the National Advisory Dental Research Council and served as a consultant and visiting lecturer at many institutions in the U.S. and abroad, including the Pan American Health Organization.  His numerous awards include the Dental Research Prize of the International Dental Federation, the Scientific Award of the International Association for Dental Research, the Distinguished Service Award of the National Institute of Dental Research, and the Secretary of Veterans' Affairs Exceptional Service Award.

Dr. Harold Fullmer Dies
We also regret to report the death on January 20, 2007 of Harold M. Fullmer, D.D.S., who was with the NIDR from 1953 until 1970.  Dr. Fullmer was the first to isolate collagenase in humans.  He held several positions at the Institute, including chief of the Section on Histochemistry and chief of the Experimental Pathology Branch. In 1970, he moved to the University of Alabama at Birmingham as director of the Institute of Dental Research and professor of dentistry and pathology. In 1987, he was made professor emeritus.  He was a Fulbright Research Scholar at the University of Adelaide in 1982.  Dr. Fullmer was chairman of the Section on Dentistry of the American Association for the Advancement of Science, president of the American Association for Dental Research and the International Association for Dental Research, and a founder and president of the International Association of Oral Pathologists. He also chaired the Dental Caries Program Advisory Committee of DHEW (1976-79).


National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

Department of Health and Human Services (HHS)   National Institutes of Health (NIH)   USA.gov