In this Issue:1. Recovery Act Funding Opportunities2. Other Funding Opportunities3. NIDCR News4. NIH/HHS News5. Science Advances
New Recovery Act Funding OpportunitiesNIH has announced several new funding opportunities that will be supported with funds made available under the American Recovery and Reinvestment Act (ARRA). For additional details, see NIDCR's ARRA website:http://www.nidcr.nih.gov/Recovery/Specifically, ARRA funds will be allocated for:Small Business Catalyst Awards for Accelerating Innovative Research (R43)The Small Business Catalyst awards focus on early stage technology development. Grant applications are invited from small business concerns who propose to accelerate innovation through high risk, high reward research and development (R&D) that has commercial potential and is relevant to NIH's mission. In particular, applications from small business concerns without a history of NIH Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) support may receive funding priority. Rather than focusing on incremental improvements of existing technologies, projects should have the potential to generate high impact results (e.g., products, processes or services) and/or innovative research applications, research tools, techniques, devices, inventions, or methodologies. NIH intends to commit at least $5 million for the Small Business Catalyst awards and anticipates that 20-25 awards will be made for FY 2010, pending the number and quality of applications received and availability of funds. Letters of intent are due August 3, 2009; applications are due September 1, 2009. For additional details see:http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-009.html New Technologies (BRDG-SPAN) Pilot Program (RC3)Grant applications are invited for a new initiative called Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program (RC3). The program aims to address the funding gap between promising R&D and the transition to market by contributing to critical funding needed by applicants to pursue the later stage research activities necessary to achieve ultimate commercialization. The goal is to accelerate the transition from research innovations and technologies to the development of products or services that will improve human health, advance NIH's mission, and create significant value and economic stimulus. The program also aims to foster partnerships among a variety of R&D collaborators working toward these goals.NIH intends to commit at least $35 million in response to this program and anticipates that at least 10 awards will be made in FY 2010, pending the number and quality of applications received and the availability of funds. Letters of intent are due August 3, 2009; applications are due September 1, 2009. For additional details see:http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-008.html Academic Research Enhancement Awards (R15)The Academic Research Enhancement Awards (AREA) are intended to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. The AREA grants will create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH programs, to contribute to the Nation's biomedical and behavioral research effort. AREA grants will support small-scale, health-related research projects proposed by faculty members of eligible, domestic institutions. Applications are due September 24, 2009. For additional details see:http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-007.htmlNIH Receives 20,000 Applications for Challenge Grants NIH has received approximately 20,000 applications for Challenge Grants, a new program under the American Recovery and Reinvestment Act (ARRA). This large number of applications is approximately equal to the total number of applications NIH receives in one of the agency’s three major review rounds each year.The Center for Scientific Review (CSR) will check the applications for compliance and review them in a two-phase process. Reviewers with expertise in the specialized topic areas were recruited to do the first phase reviews. Their reviews and the applications will be further assessed by one of about 30 study sections made up of researchers who will focus on overall significance and impact. More than 18,000 scientists are expected to be involved in the Challenge Grant peer review process. Scores and summary statements will be available in August 2009. Challenge Grant awards will be issued by September 30, 2009.
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Application Receipt Date
Recovery Act Limited Competition: Academic Research Enhancement Award (R15)
NIDCR Small Research Grants for Data Analysis and Statistical Methodology (R03)
Jane Atkinson301-435-7908Ruth Nowjack-Raymer 301-594-5394
Notice: Announcing New Business Processes and Confirming the Transition of Individual National Research Service Award (NRSA) Fellowship ("F") Applications to Electronic Submission
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (F30)
Application Receipt Date
Reminder and Clarification of NIH Policies on Similar, Identical, or Essentially Identical Applications, Submission of Applications Following RFA Review, and Submission of Applications with a Changed Activity Code
New Concept ClearancesConcepts represent early planning stages for initiatives in which NIDCR seeks to support research in an understudied and significant area of science. Approval by the National Advisory Dental and Craniofacial Research Council does not guarantee that a concept will become a program announcement (PA), request for applications (RFA), or request for proposals (RFP). NIDCR bases this determination on scientific and programmatic priorities balanced with the amount of funds available. Concept clearances approved at the May 2009 Council meeting were: Metagenomic Evaluation of Oral Polymicrobial DiseaseIncreasing the Service Life of Dental Resin CompositesNIDCR Small Research Grant for Data Analysis and Statistical Methodology: Extension to Genome-Wide DataDentist-Scientist Pathway to Independence AwardTo read more about these go to:http://www.nidcr.nih.gov/GrantsAndFunding/ and click on the 5th link under "Funding Opportunities Sorted by....." that says, "Concept Clearances (Future Research Directions)."
NIDCR's FY 2010 Congressional JustificationSee NIDCR's FY 2010 Congressional Justification:http://www.nidcr.nih.gov/AboutUs/BudgetCongressionalStatements/NIDCR's FY 2010 Budget RequestSee the NIDCR Director's Statement for the Senate Appropriations Subcommittee Regarding the FY 2010 budget request:http://www.nidcr.nih.gov/AboutUs/BudgetCongressionalStatements/Applications Accepted for Residency Program in Dental Public Health NIDCR is now accepting applications for its Residency Program in Dental Public Health. Qualified applicants with a DDS or DMD degree or its equivalent and a prerequisite graduate degree in public health are eligible to apply. The program provides a formal training opportunity for dentists planning careers in dental public health, with an emphasis on oral and craniofacial, health-related epidemiologic research. The program is accredited by the Commission on Accreditation of the American Dental Association. Graduates receive a certificate of completion and are qualified educationally to apply for examination by the American Board of Dental Public Health for specialty certification. Additional details and an application are available at:http://www.nidcr.nih.gov/CareersAndTraining/Fellowships/DentistsandPhysicians/(Click on the 1st link that says, "Residency in Dental Public Health")
Public Comment Sought on Regulations for Financial Conflicts of Interest in Federally-Funded ResearchNIH is seeking comments from the public on possible changes to the regulations regarding financial conflicts of interest in Federally-funded research. The existing regulations issued in 1995 were designed to promote objectivity in research by creating standards to ensure there is no reasonable expectation that the design, conduct, or reporting of research funded under Public Health Service grants or cooperative agreements will be biased by any conflicting financial interest on the part of the researcher. Since the publication of the current regulations, NIH has launched many initiatives to enhance effective oversight and regulatory compliance. NIH now invites public comment on all aspects of the regulation, with particular interest in potential for expanding the scope of the regulation and disclosure interests; the definition of "Significant Financial Interest;" identification and management of conflicts by institutions; assuring institutional compliance; requiring institutions to provide additional information to the PHS; and broadening the regulations to address institutional conflicts of interest. The comment period is open until July 7, 2009. NIH Announces New Program to Develop Therapeutics for Rare and Neglected DiseasesNIH is launching the first integrated drug development pipeline to produce new treatments for rare and neglected diseases. The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases program, or TRND. The program is unusual because TRND creates a drug development pipeline within the NIH and is specifically intended to stimulate research collaborations with academic scientists working on rare illnesses. The NIH Office of Rare Diseases Research will oversee the program, and TRND's laboratory operations will be administered by the National Human Genome Research Initiative, which also operates the NIH Chemical Genomics Center, a principal collaborator in TRND. Other NIH components also will participate in the initiative. A rare disease is one that affects fewer than 200,000 americans. NIH estimates that, in total, more than 6,800 rare diseases afflict more than 25 million Americans. However, effective pharmacologic treatments exist for only about 200 of these illnesses. HHS Deputy Secretary and Director of Indian Health Service Appointed On May 6, the Senate unanimously confirmed Bill Corr as Deputy Secretary of the Department of Health and Human Services (DHHS) and Dr. Yvette Roubideaux as Director of the Indian Health Service. Both will serve under the direction of Kathleen Sebelius, whose nomination as HHS Secretary was confirmed by the Senate on April 28.Previously, Bill Corr was executive director of the Campaign for Tobacco-Free Kids. He held positions as Counsel to the U.S. House of Representatives Subcommittee on Health and the Environment for 12 years and as HHS Chief of Staff. He is a graduate of the University of Virginia and Vanderbilt University School of Law. Dr. Roubideaux is a Harvard-educated physician who has conducted extensive research on American Indian health issues, with a focus on diabetes in American Indians/Alaska Natives and Indian health policy. Most recently she was an assistant professor in the Department of Family & Community Medicine at the University of Arizona College of Medicine. A member of the Rosebud Sioux tribe, she is the first woman to lead the Indian Health Service.
See the series of interviews below with NIDCR-supported health disparities researchers: http://www.nidcr.nih.gov/Research/ResearchResults/InterviewsOHR/Listening to Learn: Southeast Center for Research to Reduce Disparities in Oral Health A generation ago, cancer was a taboo subject that was often mentioned among friends in hushed tones. Today, that’s no longer the case. But public awareness has been slow to extend to the head and neck cancers, including oral cancer, particularly among the low-income and underserved Americans that are most at risk. To learn how to enhance awareness and save lives, the NIDCR began supporting the Southeast Center for Research to Reduce Disparities in Oral Health at the University of Florida’s College of Dentistry in Gainesville. See the interview with Dr. Henrietta Logan, the center’s principal investigator and a professor at the College of Dentistry.CAN DO: Center to Address Disparities in Children's Oral Health Known by its acronym CAN DO, the Center to Address Disparities in Children's Oral Health at the University of California at San Francisco is one of three NIDCR-supported centers with a primary focus on early childhood caries. CAN DO scientists are developing better ways to prevent childhood caries in California, one of the nation’s most culturally and socio-economically diverse states. As CAN DO scientists often note, the lessons learned in California will be of benefit to public health programs throughout the country. See the interview with Jane Weintraub, DDS, MPH, a researcher at the University of California at San Francisco and the center’s principal investigator and director. Disparities Research: Center for Native Oral Health ResearchMany fundamental aspects of American Indian and Native Alaskan health remain to be fully understood and systematically addressed. Numbered prominently among them is oral health. In late 2008, NIDCR began supporting a new oral health disparities center in Denver. To learn more about this center in the making, see the interview with two of its primary investigators: Judith E. N. Albino, PhD, Clinical Professor in the University of Colorado School of Public Health and the director and principal investigator of the NIDCR-supported Center for Native Oral Health Research, and Spero M. Manson, PhD, who heads the Centers for American Indian and Alaska Native Health at the University of Colorado School of Public Health and is a member of the Pembina Chippewa tribe. He is the oral health center’s associate director. A Look at Oral Health Disparities in AppalachiaIn many parts of Appalachia, tooth decay remains an unfortunate rite of childhood that too often leads to a lifetime of poor oral health. Given the troubling scope and consequences of this largely preventable problem across Appalachia, researchers are now attempting to more clearly define the causes of poor oral health in the region and develop practical, low-cost solutions. Prominent in this effort is the Center for Oral Health Research in Appalachia (COHRA). See the interview with Mary Marazita, PhD, a scientist at the University of Pittsburgh and co-principal investigator of COHRA.Science News in BriefSee the following summaries of recent oral health research findings:http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB/Scientists Explore Gene Variability in S. MutansGene Change and Aggressive Periodontitis in African Americans
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