News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: June 17, 2009

In this Issue:
1. Recovery Act Funding Opportunities
2. Other Funding Opportunities
3. NIDCR News
4. NIH/HHS News
5. Science Advances

 

 


American Recovery and Reinvestment Act Funding Opportunities

New Recovery Act Funding Opportunities
American Recovery and Reinvestment Act logo
NIH has announced several new funding opportunities that will be supported with funds made available under the American Recovery and Reinvestment Act (ARRA).  For additional details, see NIDCR's ARRA website:
http://www.nidcr.nih.gov/Recovery/


Specifically, ARRA funds will be allocated for:

Small Business Catalyst Awards for Accelerating Innovative Research (R43)
The Small Business Catalyst awards focus on early stage technology development.  Grant applications are invited from small business concerns who propose to accelerate innovation through high risk, high reward research and development (R&D) that has commercial potential and is relevant to NIH's mission.  In particular, applications from small business concerns without a history of NIH Small Business Innovation Research (SBIR) or Small Business Technology Transfer (STTR) support may receive funding priority.  Rather than focusing on incremental improvements of existing technologies, projects should have the potential to generate high impact results (e.g., products, processes or services) and/or innovative research applications, research tools, techniques, devices, inventions, or methodologies.  

NIH intends to commit at least $5 million for the Small Business Catalyst awards and anticipates that 20-25 awards will be made for FY 2010, pending the number and quality of applications received and availability of funds.  Letters of intent are due August 3, 2009; applications are due September 1, 2009.  For additional details see:
http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-009.html   

New Technologies (BRDG-SPAN) Pilot Program (RC3)
Grant applications are invited for a new initiative called Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program (RC3).  The program aims to address the funding gap between promising R&D and the transition to market by contributing to critical funding needed by applicants to pursue the later stage research activities necessary to achieve ultimate commercialization. The goal is to accelerate the transition from research innovations and technologies to the development of products or services that will improve human health, advance NIH's mission, and create significant value and economic stimulus. The program also aims to foster partnerships among a variety of R&D collaborators working toward these goals.

NIH intends to commit at least $35 million in response to this program and anticipates that at least 10 awards will be made in FY 2010, pending the number and quality of applications received and the availability of funds.  Letters of intent are due August 3, 2009; applications are due September 1, 2009.  For additional details see:
http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-008.html        

Academic Research Enhancement Awards (R15)
The Academic Research Enhancement Awards (AREA) are intended to stimulate research in educational institutions that provide baccalaureate or advanced degrees for a significant number of the Nation's research scientists, but that have not been major recipients of NIH support. The AREA grants will create opportunities for scientists and institutions otherwise unlikely to participate extensively in NIH programs, to contribute to the Nation's biomedical and behavioral research effort. AREA grants will support small-scale, health-related research projects proposed by faculty members of eligible, domestic institutions.  Applications are due September 24, 2009.  For additional details see:
http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-09-007.html

NIH Receives 20,000 Applications for Challenge Grants
NIH has received approximately 20,000 applications for Challenge Grants, a new program under the American Recovery and Reinvestment Act (ARRA). This large number of applications is approximately equal to the total number of applications NIH receives in one of the agency’s three major review rounds each year.

The Center for Scientific Review (CSR) will check the applications for compliance and review them in a two-phase process. Reviewers with expertise in the specialized topic areas were recruited to do the first phase reviews. Their reviews and the applications will be further assessed by one of about 30 study sections made up of researchers who will focus on overall significance and impact. More than 18,000 scientists are expected to be involved in the Challenge Grant peer review process.  Scores and summary statements will be available in August 2009. Challenge Grant awards will be issued by September 30, 2009.

Remember:

ORGANIZATIONS MUST REGISTER IN BOTH
GRANTS.GOV AND eRA COMMONS TO APPLY FOR MOST NIH GRANTS

Registration can take approximately four weeks to complete.  Start now!

 



See the latest ARRA Funding Opportunity Announcements

Title

NIH
Guide

Announcement Number

NIDCR Contact

Application Receipt Date

Recovery Act Limited Competition: Small Business Catalyst Awards for Accelerating Innovative Research (R43) 6/02/09 RFA-OD-09-009 R. Dwayne Lunsford
301-594-2421
Letters of intent due:
8/03/09
Applications due:
9/01/09 
Recovery Act Limited Competition: Biomedical Research, Development, and Growth to Spur the Acceleration of New Technologies (BRDG-SPAN) Pilot Program (RC3) 6/02/09 RFA-OD-09-008 R. Dwayne Lunsford
301-594-2421
Letters of intent due:
8/03/09
Applications due:
9/01/09

Recovery Act Limited Competition: Academic Research Enhancement Award (R15)

4/20/09

RFA-OD-09-007 Alicia Dombroski
301-594-4805
9/24/09

 

OTHER FUNDING OPPORTUNITIES


PROGRAM ANNOUNCEMENTS


Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

NIDCR Small Research Grants for Data Analysis and Statistical Methodology (R03)

5/04/09

PAR-09-182

Jane Atkinson
301-435-7908

Ruth Nowjack-Raymer

301-594-5394

5/08/12
NIH Exploratory/Developmental Research Grant Program (Parent R21) 4/16/09 PA-09-164 Jane Atkinson
301-435-7908

Ruth Nowjack-Raymer
301-594-5394

Lillian Shum
301-594-0618
5/08/12


Fellowships

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

Notice: Announcing New Business Processes and Confirming the Transition of Individual National Research Service Award (NRSA) Fellowship ("F") Applications to Electronic Submission 

6/12/09


Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (F30)

 

6/12/09 PA-09-207

Leslie Frieden
301-496-4263

9/08/12
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (F31)  6/12/09 PA-09-208

Leslie Frieden
301-496-4263

9/08/12
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (F31) to Promote Diversity in Health-Related Research 6/11/09 PA-09-209

Leslie Frieden
301-496-4263

9/08/12
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32)  6/12/09 PA-09-210

Leslie Frieden
301-496-4263

9/08/12
Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (F33) 6/12/09 PA-09-211

Leslie Frieden
301-496-4263

9/08/12



REQUESTS FOR APPLICATIONS

NIH Roadmap Initiatives

Title

NIH
Guide

RFA Number

NIDCR Contact

Application Receipt 
Date

Pilot-Scale Libraries (PSL) for High-Throughput Screening (P41) 5/27/09 RFA-RM-09-007 Lillian Shum
301-594-0618
10/01/09
Novel statistical methods for human gene expression quantitative trait loci (eQTL) analysis (R01)  4/01/09 RFA-RM-09-006 Lillian Shum
301-594-0618
9/16/09


NOTICES

Title

NIH
Guide

Notice Number

Announcing New Business Processes and Confirming the Transition of Individual National Research Service Award (NRSA) Fellowship ("F") Applications to Electronic Submission    6/12/09 NOT-OD-09-106

Reminder and Clarification of NIH Policies on Similar, Identical, or Essentially Identical Applications, Submission of Applications Following RFA Review, and Submission of Applications with a Changed Activity Code

5/15/09 NOT-OD-09-100
Notice of Intent to Publish a Request for Applications for The Human Connectome Project (U54) 5/12/09 NOT-MH-09-010
NIH Requests Comments on Proposed Amendment of Regulations on the Responsibility of Applicants for Promoting Objectivity in Research for which Public Health Funding is Sought and Responsible Prospective Contractors 5/08/09 NOT-OD-09-099
Revision of PA-08-191: Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers 5/08/09 NOT-OD-09-094
Revision of PA-08-190: Research Supplements to Promote Diversity in Health-Related Research 5/07/09 NOT-OD-09-093
Notice of Correction to Award Information for PAR-08-024 "Assay Development for High Throughput Molecular Screening"

5/07/09

NOT-RM-09-013

Announcing a New Business Process for Submitting Revised Project Summary/Abstracts, Specific Aims, and/or Public Health Relevance Statements when Changing the Scope of Proposed Research Projects 505/09 NOT-OD-09-088
Delays in Grant Application Submission Due to Closure of Institutions because of 2009 H1N1 Flu Concerns  5/01/09 NOT-OD-09-092
Notice of Opportunity for Fast Track Entry of Assay Projects for High Throughput Screening into the NIH Roadmap Molecular Libraries Probe Production Centers Network 4/27/09 NOT-RM-09-011
Extension of the Expiration Date for PA-06-042 the Academic Research Enhancement Award  (AREA): R15 4/20/09 NOT-OD-09-084
Implementation of Executive Order on Removing Barriers to Responsible Scientific Research Involving Human Stem Cells  4/17/09 NOT-OD-09-085
Recovery Act of 2009: NIH Award Terms and Additional Information for Recipients Receiving Recovery Act Grant Funding 4/03/09 NOT-OD-09-080
Recovery Act Notice: NIH ARRA Funding Considerations for Applications with Meritorious Scores that Fall Beyond the Pay-line   4/03/09 NOT-OD-09-078
Ruth L. Kirschstein National Research Service Award (NRSA) Stipend and Other Budgetary Levels Effective for Fiscal Year 2009  3/27/09 NOT-OD-09-075
Enhancing Peer Review:  The NIH Announces Consolidation of Review Criteria for Institutional Research Training Grant Applications (T32) Submitted for FY 2010 Funding 3/27/09 NOT-OD-09-074
NIH Requires Mandatory Use of the eRA Commons Financial Conflict of Interest (FCOI) Module Beginning July 1, 2009 for NIH-funded Grants and/or Cooperative Agreements  3/27/09 NOT-OD-09-072


New Concept Clearances
Concepts represent early planning stages for initiatives in which NIDCR seeks to support research in an understudied and significant area of science.  Approval by the National Advisory Dental and Craniofacial Research Council does not guarantee that a concept will become a program announcement (PA), request for applications (RFA), or request for proposals (RFP).  NIDCR bases this determination on scientific and programmatic priorities balanced with the amount of funds available. 

Concept clearances approved at the May 2009 Council meeting were: 
Metagenomic Evaluation of Oral Polymicrobial Disease
Increasing the Service Life of Dental Resin Composites
NIDCR Small Research Grant for Data Analysis and Statistical Methodology: Extension to Genome-Wide Data
Dentist-Scientist Pathway to Independence Award

To read more about these go to:
http://www.nidcr.nih.gov/GrantsAndFunding/ 
and click on the 5th link under "Funding Opportunities Sorted by....." that says, "Concept Clearances (Future Research Directions)."

NIDCR NEWS

NIDCR's FY 2010 Congressional Justification
See NIDCR's FY 2010 Congressional Justification:
http://www.nidcr.nih.gov/AboutUs/BudgetCongressionalStatements/

NIDCR's FY 2010 Budget Request
See the NIDCR Director's Statement for the Senate Appropriations Subcommittee Regarding the FY 2010 budget request:
http://www.nidcr.nih.gov/AboutUs/BudgetCongressionalStatements/

Applications Accepted for Residency Program in Dental Public Health 
NIDCR is now accepting applications for its Residency Program in Dental Public Health. Qualified applicants with a DDS or DMD degree or its equivalent and a prerequisite graduate degree in public health are eligible to apply. The program provides a formal training opportunity for dentists planning careers in dental public health, with an emphasis on oral and craniofacial, health-related epidemiologic research. The program is accredited by the Commission on Accreditation of the American Dental Association.  Graduates receive a certificate of completion and are qualified educationally to apply for examination by the American Board of Dental Public Health for specialty certification.  

Additional details and an application are available at:
http://www.nidcr.nih.gov/CareersAndTraining/Fellowships/DentistsandPhysicians/
(Click on the 1st link that says, "Residency in Dental Public Health") 

NIH/HHS NEWS

Public Comment Sought on Regulations for Financial Conflicts of Interest in Federally-Funded Research
NIH is seeking comments from the public on possible changes to the regulations regarding financial conflicts of interest in Federally-funded research.  The existing regulations issued in 1995 were designed to promote objectivity in research by creating standards to ensure there is no reasonable expectation that the design, conduct, or reporting of research funded under Public Health Service grants or cooperative agreements will be biased by any conflicting financial interest on the part of the researcher. 

Since the publication of the current regulations, NIH has launched many initiatives to enhance effective oversight and regulatory compliance.  NIH now invites public comment on all aspects of the regulation, with particular interest in potential for expanding the scope of the regulation and disclosure interests; the definition of "Significant Financial Interest;" identification and management of conflicts by institutions; assuring institutional compliance; requiring institutions to provide additional information to the PHS; and broadening the regulations to address institutional conflicts of interest. The comment period is open until July 7, 2009.  

       
NIH Announces New Program to Develop Therapeutics for Rare and Neglected Diseases
NIH is launching the first integrated drug development pipeline to produce new treatments for rare and neglected diseases.  The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases program, or TRND.  The program is unusual because TRND creates a drug development pipeline within the NIH and is specifically intended to stimulate research collaborations with academic scientists working on rare illnesses.  The NIH Office of Rare Diseases Research will oversee the program, and TRND's laboratory operations will be administered by the National Human Genome Research Initiative, which also operates the NIH Chemical Genomics Center, a principal collaborator in TRND.  Other NIH components also will participate in the initiative. 

A rare disease is one that affects fewer than 200,000 americans.  NIH estimates that, in total, more than 6,800 rare diseases afflict more than 25 million Americans.  However, effective pharmacologic treatments exist for only about 200 of these illnesses.    

HHS Deputy Secretary and Director of Indian Health Service Appointed
 
On May 6, the Senate unanimously confirmed Bill Corr as Deputy Secretary of the Department of Health and Human Services (DHHS) and Dr. Yvette Roubideaux as Director of the Indian Health Service.  Both will serve under the direction of Kathleen Sebelius, whose nomination as HHS Secretary was confirmed by the Senate on April 28.

Previously, Bill Corr was executive director of the Campaign for Tobacco-Free Kids.  He held positions as Counsel to the U.S. House of Representatives Subcommittee on Health and the Environment for 12 years and as HHS Chief of Staff.  He is a graduate of the University of Virginia and Vanderbilt University School of Law.
 
Dr. Roubideaux is a Harvard-educated physician who has conducted extensive research on American Indian health issues, with a focus on diabetes in American Indians/Alaska Natives and Indian health policy.  Most recently she was an assistant professor in the Department of Family & Community Medicine at the University of Arizona College of Medicine.  A member of the Rosebud Sioux tribe, she is the first woman to lead the Indian Health Service.

SCIENCE ADVANCES

See the series of interviews below with NIDCR-supported health disparities researchers:  
http://www.nidcr.nih.gov/Research/ResearchResults/InterviewsOHR/

Listening to Learn: Southeast Center for Research to Reduce Disparities in Oral Health 
smiling African American manA generation ago, cancer was a taboo subject that was often mentioned among friends in hushed tones.  Today, that’s no longer the case.  But public awareness has been slow to extend to the head and neck cancers, including oral cancer, particularly among the low-income and underserved Americans that are most at risk.  To learn how to enhance awareness and save lives, the NIDCR began supporting the Southeast Center for Research to Reduce Disparities in Oral Health at the University of Florida’s College of Dentistry in Gainesville.  See the interview with Dr. Henrietta Logan, the center’s principal investigator and a professor at the College of Dentistry.

CAN DO:  Center to Address Disparities in Children's Oral Health 
Smiling 5-year-old boyKnown by its acronym CAN DO, the Center to Address Disparities in Children's Oral Health at the University of California at San Francisco is one of three NIDCR-supported centers with a primary focus on early childhood caries.  CAN DO scientists are developing better ways to prevent childhood caries in California, one of the nation’s most culturally and socio-economically diverse states.  As CAN DO scientists often note, the lessons learned in California will be of benefit to public health programs throughout the country.  See the interview with Jane Weintraub, DDS, MPH, a researcher at the University of California at San Francisco and the center’s principal investigator and director.

Disparities Research: Center for Native Oral Health Research
Center for Native Oral Health Research logoMany fundamental aspects of American Indian and Native Alaskan health remain to be fully understood and systematically addressed.  Numbered prominently among them is oral health.  In late 2008, NIDCR began supporting a new oral health disparities center in Denver. To learn more about this center in the making, see the interview with two of its primary investigators:  Judith E. N. Albino, PhD, Clinical Professor in the University of Colorado School of Public Health and the director and principal investigator of the NIDCR-supported Center for Native Oral Health Research, and Spero M. Manson, PhD, who heads the Centers for American Indian and Alaska Native Health at the University of Colorado School of Public Health and is a member of the Pembina Chippewa tribe.  He is the oral health center’s associate director.
 
A Look at Oral Health Disparities in Appalachia
COHRA logoIn many parts of Appalachia, tooth decay remains an unfortunate rite of childhood that too often leads to a lifetime of poor oral health. Given the troubling scope and consequences of this largely preventable problem across Appalachia, researchers are now attempting to more clearly define the causes of poor oral health in the region and develop practical, low-cost solutions.  Prominent in this effort is the Center for Oral Health Research in Appalachia (COHRA).  See the interview with Mary Marazita, PhD, a scientist at the University of Pittsburgh and co-principal investigator of COHRA.

Science News in Brief
See the following summaries of recent oral health research findings:
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB/

Scientists Explore Gene Variability in S. Mutans
Gene Change and Aggressive Periodontitis in African Americans


National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

Department of Health and Human Services (HHS)   National Institutes of Health (NIH)   USA.gov