News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: February 5, 2010

In this Issue:
1. American Reinvestment and Recovery Act News
2. Funding Opportunity News
3. NIDCR News
4. NIH News
5. Science Advances

 

 


AMERICAN REINVESTMENT AND RECOVERY ACT NEWS

Limited Competition: NIH Director's Opportunity for Research in 5 Thematic Areas (RC4)
ARRA logoUsing new ARRA funds received for FY 2009 and 2010, NIH is establishing a program called the "NIH Director's Opportunity for Research in Five Thematic Areas."  The five areas are:







  • Applying Genomics and Other High Throughput Technologies
  • Translating Basic Science Discoveries into New and Better Treatments
  • Using Science to Enable Health Care Reform
  • Focusing on Global Health
  • Reinvigorating the Biomedical Research Community     

The program will support projects that address research in these areas that will benefit from significant three-year funds without the expectation of continued NIH funding beyond this period.  The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery.  Contingent upon the submission of a sufficient number of scientifically meritorious applications, up to $80 million of ARRA funds will be obligated by September 30, 2010 to support requests in response to this Funding Opportunity Announcement (FOA).  Only applications with budgets greater than $500,000 total costs per year for a project period of three years are expected to be considered.  The earliest date an application may be submitted to Grants.gov is February 15, 2010.  Letters of Intent are due February 15; applications are due by March 15.  For additional information see:
http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-10-005.html


Funding Opportunities Available through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet)
On November 18, NIH Director Francis S. Collins announced the launch of OppNet --the NIH Basic Behavioral and Social Science Opportunity Network, a trans-NIH initiative to expand the agency's funding of basic behavioral and social sciences research (b-BSSR):
http://oppnet.nih.gov/
OppNet has received $10 million in ARRA funds for its inaugural year. Approximately $2 million of this amount will be dedicated to short-term mentored career development awards for mid-career and senior investigators:

  • Limited Competition: NIH Basic Behavioral and Social Science Opportunity Network (OppNet) Short-term Mentored Career Development Awards in the Basic Behavioral and Social Sciences for Mid-career  and Senior Investigators (K18)
    Applications are invited for short-term mentored career development (K18) awards in basic behavioral and social sciences research (b-BSSR) from three months to one year in duration.  The program aims to support the development of b-BSSR research capability in established mid-career and senior investigators. Two categories of candidates are targeted: (a) biomedical or clinical researchers with little experience in basic behavioral and social sciences research who seek training with a well established b-BSSR investigator to explore the introduction of b-BSSR into their research programs; and (b) investigators in the basic or applied behavioral and social sciences who wish to build new components or domains of basic-BSSR into their research programs. It is anticipated that 10-20 awards will be made for fiscal year 2010, pending the number and quality of applications and availability of funds.  Applications are due February 18th.  For additional information see:
    http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-10-003.html


OppNet's remaining $8 million in ARRA funds will be obligated by September 30, 2010 to support competitive revision requests submitted in response to the following three Notices: 

  • Competitive Revision Applications (R01, R03, R15, R21, R21/33, and R37)
    Investigators and U.S. institutions/organizations with relevant active NIH-support research project grants (R01, R03, R15, R21, R21/33, and R37) are invited to submit competitive revision applications (formerly termed competitive supplements) to accelerate, expand, and/or strengthen basic behavioral and social sciences research.  Applications are due March 2, 2010. For additional details see:
    http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-032.html

  • Competitive Revision Applications (R01, R03, R15, R21, R21/33, and R37) for HIV/AIDS-related Research
    Investigators and U.S. institutions/organizations with relevant NIH-supported research project grants (R01, R03, R15, R21, R21/33, and R37) are invited to submit competitive revision applications to accelerate, expand, and/or strengthen basic behavioral and social sciences research relevant to HIV/AIDS risk, prevention, and treatment.  Applications are due March 25, 2010. For additional information see:
    http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-033.html

  • Competitive Revision Applications for Small Business Innovation Research and Small Business Technology Transfer Research Grants (R43/R44 and R41/R42)
    Investigators and U.S. institutions/organizations with relevant active NIH-supported small business research project grants (STTR [R41, R42], SBIR [R43,R44], and SBIR/STTR Fast-Track grants) may submit competitive revision applications to accelerate innovation through basic behavioral and social sciences research and development that has commercial potential and is relevant to OppNet’s mission.  Applications are due March 25, 2010. For additional information see:
    http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-034.html
    Also see clarification of Notice:
    http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-054.html

Recovery Act Limited Competition: Institutional Comparative Effectiveness Research Mentored Career Development Award (KM1)
This FOA aims to support the expansion of the nation’s workforce of researchers with expertise and experience in comparative effectiveness research (CER). The mentored career development approach will permit research-intensive institutions to develop an interdisciplinary environment catering to the needs of diverse populations of scholars including (but not limited to) those with backgrounds in biostatistics, epidemiology, health economics, pharmacology, medicine, and dentistry. Scholars supported through this program could include recent doctoral graduates who are entering the research workforce as well as established investigators who are seeking to extend their expertise or experience in CER in a mentored environment.  NIH intends to commit up to $25,000,000 for this FOA.  It is anticipated that eight to 10 awards will be made for Fiscal Year 2010, pending the number and quality of applications.  Applications are due March 25, 2010.  See more information at:
http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-10-011.html


ARRA OS: Recovery Act 2009: Accelerating Adoption of Comparative Effectiveness Research Results by Providers and Patients (R18)
Applications are invited from organizations that propose to develop and test strategies to improve the adoption of existing CER information and to incorporate these findings into practice in both the public and private sector.  Funds will be used to support organizations that 1) develop and test evidence-informed and innovative CER-based adoption interventions targeting patients and/or providers; 2) develop proposals that test the implementation of CER-based adoption strategies within and across organizations and delivery systems and analyze any behavior change (in patients and/or providers) associated with the intervention. It is anticipated that 5-10 awards will be made.  Applications are due March 11, 2010.  See additional details at:
http://grants.nih.gov/grants/guide/rfa-files/RFA-AE-10-001.html

Availability of Recovery Act Funds for Administrative Supplements for Comparative Effectiveness Research Workforce Development
Investigators and U.S. institutions/organizations with active NIH research grants may request administrative supplements for the purpose of expanding the numbers of researchers qualified to oversee or conduct comparative effectiveness research (CER).  The receipt date is March 1, 2010 and the maximum sum that may be requested is $500,000 in total costs.  Up to 16 awards may be made. Information about the NIH CER-specific areas of interest, process for submitting requests, and selection criteria is found at:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-037.html

Availability of Recovery Act Funds for Administrative Supplements to Support Core Consolidation
Investigators and U.S. institutions/organizations with certain active NIH research grants that support core facilities were invited to request administrative supplements for the purpose of consolidating multiple cores into a single, more efficient core. Approximately $15 million of ARRA funds will be obligated by September 30, 2010 to support requests submitted in response to this notice.  Support could be requested for up to 1 year for qualified grants.  It is expected that this will be a one-time opportunity. For additional information see:
http://grants.nih.gov/grants/guide/notice-files/NOT-RR-10-001.html


FUNDING OPPORTUNITY NEWS


NEW PROGRAM ANNOUNCEMENTS

Behavioral/Social Science Research

 

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

Dissemination and Implementation Research in Health (R01) 
( also see Health Disparities)
12/01/09 PAR-10-038 Ruth Nowjack-Raymer
301-594-5394
1/08/13
Dissemination and Implementation Research in Health (R03)
( also see Health Disparities)
12/01/09 PAR-10-039 Ruth Nowjack-Raymer
301-594-5394
1/08/13
Dissemination and Implementation Research in Health (R21)
( also see Health Disparities)
12/01/09 PAR-10-040 Ruth Nowjack-Raymer
301-594-5394
1/08/13



Clinical Research/Clinical Trials

 

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

NIH Exploratory/Developmental Research Grant Program (Parent R21) 12/24/09 PA-10-069 Jane Atkinson
301-435-7908
1/08/13


Gene Studies



 

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

NIDCR Small Research Grants for Data Analysis and Statistical Methodology applied to Genome-wide Data (R03) 12/01/09 PAR-10-041 Emily Harris
301-594-4846 
1/08/13

Health Disparities

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

Dissemination and Implementation Research in Health (R01)
( also see Behavioral/Social Science Research)
12/01/09 PAR-10-038 Ruth Nowjack-Raymer
301-594-5394
1/08/13
Dissemination and Implementation Research in Health (R03)
( also see Behavioral/Social Science Research)
12/01/09 PAR-10-039 Ruth Nowjack-Raymer
301-594-5394
1/08/13
Dissemination and Implementation Research in Health (R21)
( also see Behavioral/Social Science Research)
12/01/09 PAR-10-040 Ruth Nowjack-Raymer
301-594-5394
1/08/13

Research Mechanisms

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

PHS 2010-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44])   1/15/10 PA-10-050

R. Dwayne Lunsford
301-594-2421

1/08/11
PHS 2010-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]) 1/15/10 PA-10-051

R. Dwayne Lunsford
301-594-2421

1/08/11
Research Project Grant (Parent R01) 12/17/09 PA-10-067 Lillian Shum
301-594-0618
1/08/13
NIH Exploratory/Developmental Research Grant Program (Parent R21)  12/24/09 PA-10-069

Lillian Shum
301-594-0618


Jane Atkinson
301-435-7908

Emily Harris
301-594-4846

Melissa Riddle
301-451-3888
1/08/13
NIH Support for Conferences and Scientific Meetings (Parent R13/U13) 1/04/10 PA-10-071 Alicia Dombroski
301-594-4805
1/08/13
Academic Research Enhancement Award (Parent R15) 12/24/09 PA-10-070 Alicia Dombroski
301-594-4805
1/08/13

Career Development

Title

NIH
Guide

PA
Number

NIDCR Contact

Expiration
Date

Independent Scientist Award (Parent K02) 12/16/09 PA-10-057 Kevin Hardwick
301-594-2765
1/08/13
Mentored Clinical Scientist Research Career Development Award (Parent K08) 12/16/09 PA-10-059 Kevin Hardwick
301-594-2765
1/08/13
Mentored Patient-Oriented Research Career Development Award (Parent K23) 12/17/09 PA-10-060 Kevin Hardwick
301-594-2765
1/08/13
Midcareer Investigator Award in Patient-Oriented Research (Parent K24)   12/16/09 PA-10-061 Kevin Hardwick
301-594-2765
1/08/13
Mentored Quantitative Research Development Award (Parent K25) 12/17/09 PA-10-062 Kevin Hardwick
301-594-2765
1/08/12
NIH Pathway to Independence Award (Parent K99/R00) 12/16/09 PA-10-063 Leslie Frieden
301-496-4263
1/08/13





NEW REQUESTS FOR APPLICATIONS

American Reinvestment and Recovery Act


Title

NIH
Guide

RFA Number

NIDCR Contact

Application Receipt Date

Recovery Act Limited Competition: Institutional Comparative Effectiveness Research Mentored Career Development Award (KM1) 1/13/10 RFA-OD-10-011

Kevin Hardwick
301-594-2765

3/25/10
ARRA OS: Recovery Act 2009: Accelerating Adoption of Comparative Effectiveness Research Results by Providers and  Patients (R18) 1/08/10 RFA-AE-10-001 Holli Hamilton
301-451-3852
3/11/10
Recovery Act Limited Competition: NIH Basic Behavioral and Social Science Opportunity Network (OppNet) Short-term Mentored Career Development Awards in the Basic Behavioral and Social Sciences for Mid-career and Senior Investigators (K18)  1/05/10 RFA-OD-10-003 David Clark
301-594-4814
2/18/10
Recovery Act Limited Competition: NIH Director's Opportunity for Research in Five Thematic Areas (RC4) 12/28/09 RFA-OD-10-005

Lillian Shum
301-594-0618

3/15/10




Neurobiology/Pain

Title

NIH
Guide

RFA 
Number

NIDCR Contact

Application Receipt Date

Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25) 12/04/09 RFA-MH
-10-070
John Kusiak
301-594-7984
3/24/10




NIH Roadmap

 

Title

NIH
Guide

RFA Number

NIDCR Contact

Application Receipt Date

Institutional Clinical and Translational Science Award (U54) 1/26/10 RFA-RM-10-001 Jane Atkinson
301-435-7908
10/14/10
Membrane Protein Production for Structure Determination (R01) 12/03/09 RFA-RM-09-012

John Kusiak
301-594-7984

2/11/10




NOTICES


 

Title

NIH
Guide

Notice Number

Request for Information (RFI): To Solicit Input on Priorities for the NIH Basic Behavioral and Social Science Opportunity Network (OppNet) 1/28/10 NOT-OD-10-055
Notice of Availability of Administrative Supplements for R25 Science Education Grants 1/26/10 NOT-DA-10-007
Clarification of NOT-OD-10-034: Availability of Recovery Act Funds for Competitive Revision Applications for Small Business Innovation Research and Small Business Transfer Technology Research Grants (R43/R44 and R41/R42) through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet)   1/26/10 NOT-OD-10-054
Clarification of SF424 (R&R) Application Instructions for Resubmissions of Revision and Renewal Applications 1/22/10 NOT-OD-10-052
FY2010 Recovery Act Funding Announcements: Clarification on Page Limitations for Bibliography and References Cited Section 1/22/10 NOT-OD-10-051
Clarification on the Extended Error Correction Window and Format of the Research Strategy Section for Restructured Applications Intended for Due Dates on or After January 25, 2010 1/21/10 NOT-OD-10-050
Proposed FDA Rulemaking on Informed Consent Requirements 1/15/10 NOT-OD-10-046
Ruth L. Kirschstein National Research Service Award (NRSA) Stipends, Tuition/Fees and Other Budgetary Levels Effective for Fiscal Year 2010  1/13/10 NOT-OD-10-047
NIH Broadens Eligibility for NIH Diversity and Re-Entry Supplements 1/11/10 NOT-OD-10-045
IACUC 101 and 201 PLUS Workshops: February 24-25, 2010 in Lafayette, LA 1/11/10 NOT-OD-10-044
NIH Fiscal Policy for Grant Awards - FY 2010 1/08/10 NOT-OD-10-039
Error-Correction Window Extended for Electronic Applications Intended for Submission Deadlines On and Between January 25 and May 7, 2010 1/08/10 NOT-OD-10-042
NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications for Small Business Innovation Research and Small Business Transfer Technology Research Grants (R43/R44 and R41/R42) through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet)    1/07/10 NOT-OD-10-034
NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications (R01, R03, R15, R21, R21/R33, and R37) for HIV/AIDS-related Research through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet) 1/07/10 NOT-OD-10-033
NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications (R01, R03, R15, R21, R21/R33, and R37) through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet) 1/07/10 NOT-OD-10-032
NIH Announces the Availability of HIV/AIDS Funds for Competitive Revision Applications (R01, R03, R21, R21/R33, R37) for HIV/AIDS-related Research through the NIH Basic Behavioral and Social Science Opportunity Network (OppNet) 1/07/10 NOT-OD-10-036
Salary Limitation on Grants, Cooperative Agreements, and Contracts  1/06/10 NOT-OD-10-041
Notice of Legislative Mandates in Effect for FY2010 1/06/10 NOT-OD-10-040
Implementation of the Federal Financial Report (SF-425) - Interim Guidance 1/05/10 NOT-OD-10-038
NIH Announces the Availability of Recovery Act Funds for Administrative Supplements for Comparative Effectiveness Research Workforce Development 1/04/10 NOT-OD-10-037
Availability of Reissued Parent Announcements for Due Dates on or after January 25, 2010 12/17/09 NOT-OD-10-031
Clarification of Terms and Conditions of Awards using Human Embryonic Stem Cells 12/14/09 NOT-OD-10-029
NIH Guidance under the FY 2010 Continuing Resolution -- Additional Prohibition on Use of Funds 12/03/09 NOT-OD-10-024
2010 NIH Regional Seminars on Program Funding and Grants Administration: Philadelphia, PA & Portland, OR 12/03/09 NOT-OD-10-025
First Human Embryonic Stem Cells Approved for use under the NIH Guidelines for Human Stem Cell Research 12/02/09 NOT-OD-10-020
Now Available: Restructured Application Forms and Instructions for Application Due Dates on or after January 25, 2010 11/23/09 NOT-OD-10-016
Update on the Requirement for Instruction in the Responsible Conduct of Research 11/24/09 NOT-OD-10-019
RFA Amendment: Recovery Act Limited Competition: Building Sustainable Community-Linked Infrastructure to Enable Health Science Research (RC4) 11/20/09 NOT-OD-10-017
NIH Announces the Availability of Recovery Act Funds for Administrative Supplements to Support Core Consolidation 11/06/09 NOT-RR-10-001
Non-Competing Grant Awards under the Continuing Resolution 11/05/09 NOT-OD-10-012
Revised PHS 416-9 Progress Report for Continuation Support for the Individual Fellowship Ruth L. Kirschstein National Research Service Award Now Available - Change for Human Embryonic Stem Cells Implemented 11/04/09 NOT-OD-10-011
Electronic Streamlined Noncompeting Award Process (eSNAP) Error in Report Image 10/30/09 NOT-OD-10-010
Until further notice, only papers written in Latin script will be collected via the NIH Manuscript Submission System for the NIH Public Access Policy 10/30/09 NOT-OD-10-009


 

NIDCR NEWS  

Dr. Julio Frenk Discusses Global Health
Julio Frenk, M.D., Ph.D.Dr. Julio Frenk, dean of the Harvard School of Public Health, spoke about "Globalization and Health: The Role of Knowledge in an Interdependent World" when he delivered the David E. Barmes Global Health Lecture on the NIH campus on December 15th.  The annual Barmes Lecture is jointly sponsored by the NIDCR and the Fogarty International Center.  Listen to what Dean Frenk had to say:
http://videocast.nih.gov/Summary.asp?File=15501

Temple University School of Dentistry: Empowering Communities

Amid I. Ismail, BDS, MPH, MBA, DrPH It may take a village to raise a child, but a growing number of researchers say it may take a systems approach to address long-standing inequities in the nation's oral health.  Read the interview with Dr. Amid Ismail, dean of the Maurice H. Kornberg School of Dentistry at Temple University in Philadelphia:


http://www.nidcr.nih.gov/Research/ResearchResults/InterviewsOHR/Temple.htm
 

NIH NEWS

First Human Embryonic Stem Cells Approved for Use Under NIH Guidelines
Stem cellsOn December 2, NIH Director Francis S. Collins announced the approval of the first 13 human embryonic stem cell (hESC) lines for use in NIH-funded research under the NIH Guidelines for Human Stem Cell Research adopted in July 2009.  Children's Hospital Boston developed 11 of the approved lines and Rockefeller University in New York City developed two.  An additional 96 lines have been submitted to NIH for either internal administrative review or consideration by the external Working Group for Human Embryonic Stem Cell Eligibility Review and the NIH Advisory Committee to the Director.  See additional details:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-10-020.html

NIH Opens Website for Submission of Human Embryonic Stem Cell Lines for Approval
NIH is now accepting requests for human embryonic stem cell (hESC) lines to be approved for use in NIH-funded research.  Information may be submitted through NIH Form 2890, an interactive Web form, which is found at:  
http://stemcells.nih.gov/
 


NIH Announces Expansion of Rare Diseases Clinical Research Network
NIH has announced a second phase of the Rare Diseases Clinical Research Network (RDCRN) that includes funds for 19 research consortia. The Rare Diseases Clinical Research Consortia and a Data Management Coordinating Center (DMCC) will be awarded a total of just over $117 million over the next five years to explore the natural history, epidemiology, diagnosis, and treatment of more than 95 rare diseases. 

A rare disease is defined as a disease or condition affecting fewer than 200,000 persons in the United States. Approximately 6,500 such disorders have been identified, affecting an estimated 25 million Americans. Funds and scientific oversight for the RDCRN will be provided by the Office of Rare Diseases Research and seven NIH Institutes, including the NIDCR.  Also participating are the National Institute of Neurological Disorders and Stroke (NINDS), the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute of Allergy and Infectious Diseases (NIAID), the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and the National Heart, Lung and Blood Institute (NHLBI).


NIH Announces First National Research Study Recruitment Registry
ResearchMatch.org logoIndividuals who wish to participate in research studies now can connect online with researchers nationwide through the first volunteer recruitment registry.  ResearchMatch.org is a not-for-profit secure Web site, designed to provide people who are interested in participating in research the opportunity to be matched with studies that may be the right fit for them.  The site is a collaborative effort of the national network of medical research institutions affiliated with the Clinical and Translational Science Awards (CTSAs).  The CTSA program focuses on enhancing local and national efforts to enhance the translation of laboratory discoveries into treatments for patients. Additional details about the recruitment registry are found at:
http://www.nih.gov/news/health/nov2009/ncrr-10.htm


NIH Saddened by Death of Dr. Ruth Kirschstein
Dr. Ruth Kirschstein, former NIH Deputy Director, acting NIH Director, and senior advisor to multiple NIH Directors, died on October 6.  Her scientific and Ruth Kirschstein, M.D.administrative public service career spanned more than half a century. Dr. Kirschstein conducted important laboratory work on the polio vaccine and later made history as the first woman to direct an NIH institute, the National Institute of General Medical Sciences (NIGMS).  Dr. Kirschstein was a strong advocate for research training, especially interdisciplinary predoctoral programs and programs to increase the number of minority biomedical scientists, physician-scientists, and scientists trained in emerging or evolving areas. She also personally mentored a significant number of people within and outside NIH.  In 2002, as a tribute to her many years of exceptional service to the nation, particularly in the area of research training, Congress renamed the National Research Service Award program in her honor.


NIDCR Mourns Dr. Ann Sandberg
Ann Sandberg, Ph.D.
Ann L. Sandberg, Ph.D., an internationally recognized immunologist who retired from NIDCR in 2005, died December 31, 2009 in Bozeman, Montana.  She was 71.  Dr. Sandberg was with NIDCR for 33 years; at the time of her retirement she was acting director of the Center for Integrative Craniofacial Research.  She leaves behind a legacy of scientific and personal accomplishments, and a host of colleagues and friends who celebrate her life and mourn her loss. 

"Ann Sandberg was a true pioneer--at a time when relatively few women were scientists, Ann was a leader in the field of oral infectious disease," said Dr. Lawrence Tabak, director of the NIDCR.  "Following her tenure as an intramural investigator, Ann joined the NIDCR extramural program where she markedly enhanced the Institute's portfolio in oral cancer research," he said.  "I was delighted when Ann agreed to assume a larger leadership role as the director of the Center for Integrative Craniofacial Research.  Her extraordinary leadership skills and "matter of fact" approach to dealing with challenges helped the Institute markedly enhance research investments in "omic" biology during her tenure."


Dr. Susan Shurin Named NHLBI Acting Director
Susan Shurin, M.D.Susan Shurin, M.D., was named Acting Director of the National Heart Lung and Blood Institute, effective December 1. Dr. Elizabeth Nabel, who had headed the Institute, left on November 30 to assume a new position in Boston.  Dr. Shurin is a pediatric hematologist and oncologist who held appointments as professor of pediatrics and professor of oncology at Case Western Reserve University prior to coming to the NIH and NHLBI in 2006.
 





Dr. Alan Guttmacher Named NICHD Acting Director
Alan Guttmacher, M.D.Alan Guttmacher, M.D., is the new Acting Director of NICHD, effective December 1.  A pediatrician and medical geneticist, he served in a number of roles at the National Human Genome Research Institute (NHGRI) since joining the Institute in 1999.  He became NHGRI’s Deputy Director in 2002 and served as the Institute’s Acting Director since 2008.  He replaces Susan L. Shurin, M.D., who left the NICHD to serve as acting director of NHLBI.





Dr. Eric Green Named Director of the National Human Genome Research Institute

Eric Green, M.D., Ph.D.Eric D. Green, M.D. Ph.D., is the new director of the NHGRI.  Previously he was NHGRI's scientific director and director of the Institute’s Division of Intramural Research.  Since the early 1990s, Dr. Green’s research program has been at the forefront of efforts to map, sequence, and understand complex genomes.  His work included significant, start-to-finish involvement in the Human Genome Project.  More recently, he established a program in comparative genomics that involves the generation and analyses of sequences from targeted genomic regions in evolutionarily diverse species.  The resulting data have provided new insights about vertebrate genome organization and evolution, and revealed how conserved sequences can be used to identify important functional genomic elements.
 

SCIENCE ADVANCES

Scientists Profile Oral Mycobiome
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB/
Distribution of fungi in oral rinse samples from 20 healthy individualsThousands of microorganisms inhabit the mouth, including various fungi.  Scientists provide the first comprehensive snapshot of the oral fungal community, also called mycobiome.




Lip Prints:  Something Old, Something New
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB/
lower lip whorlsLip patterns have been used to solve crimes.  They may also one day help to detect inherited risk for nonsyndromic cleft lip and/or palate.





Key Gene in Cleft Lip and/or Palate Identified
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB/
Map of chromosomal region that contains FOXE1Scientists already have identified a number of genes involved in cleft lip and/or palate.  Here's one more, and it appears to be a major player in the clefting process.





Proteomics of Saliva and Plasma
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/CurrentSNIB /
Array view of human salivary proteomeSaliva and plasma are critical bodily fluids.  Scientists are casting a wide investigative net to see how their protein content overlaps and differs.





Selectively Removing Tooth Decay
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/Archive/
Near infra-red image of decayDentists have long drilled and filled cavities.  The union of high-powered technologies could one day take the cavity out of treating tooth decay.





Resolvin Inflammation
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/Archive/

Resolvin D2 Better ways to control inflammation will help millions of Americans.  Scientists have just characterized a molecule that naturally helps our bodies resolve inflammation.






A Case for Tailored Care
http://www.nidcr.nih.gov/Research/ResearchResults/ScienceBriefs/Archive/
A future of biology-based dentistry is en route.  Here's a preview oral squamous cell carcinomaof what the future will bring to improve the diagnosis of oral cancer.





 

 

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National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

Department of Health and Human Services (HHS)   National Institutes of Health (NIH)   USA.gov