In this Issue:
NIDCR 2014-2019 Strategic Plan Update Development of the NIDCR 2014-2019 Strategic Plan continues. In June, NIDCR hosted two roundtable discussions as part of the Strategic Planning process. One focused on fostering bidirectional communication between clinicians and researchers, exploring strategies to allow observations about the nature and progression of disease made in the course of patient care and clinical research to stimulate new basic research investigations. Participants discussed individual experiences with bidirectional research, areas of research that are ripe for the application of bidirectional approaches, devising models for such research, and NIDCR’s role in its facilitation. The other focused on health disparities, a critical area because of persistent disparities in the health status of underserved Americans. The health disparities roundtable summary is found at:http://go.usa.gov/DnaVThe bidirectional research roundtable summary may be viewed at:http://go.usa.gov/DnCkIn addition, an online Request for Information was posted on the NIDCR website from July 18 -September 20, providing an opportunity for all stakeholders – including clinicians, researchers, educators, patients, advocates, and members of the public – to share their opinions about areas of research emphasis, future research approaches, and needs and opportunities. An NIDCR Strategic Plan Steering Committee has now been formed that will assess the comments received and provide input into the development of the Plan. The initial framework of the Strategic Plan will be completed by fall 2013, and the final Plan will be released in early 2014. NIDCR Director's Report to the National Advisory Dental and Craniofacial Research Council Provides NIDCR/NIH Snapshot To learn about NIDCR programmatic news and activities, the budget, recent science advances, and NIH highlights, read the report the NIDCR Director presented at the September 9, 2013 meeting of the National Advisory Dental and Craniofacial Research Council: http://go.usa.gov/DfNTRoundtable on the Temporomandibular Joint in Health and DiseaseOn May 3rd, NIDCR sponsored a roundtable meeting on the biology of the temporomandibular joint, together with the National Institute of Arthritis and Musculoskeletal and Skin Diseases and the National Institute of Biomedical Imaging and Bioengineering. The meeting brought together scientists with expertise in areas related to the structures and tissues of the temporomandibular joint to explore new research approaches to advance our understanding of temporomandibular joint function. The goal was to provide a set of research recommendations to the scientific community that will develop and create a path forward in contemporary, multidisciplinary research on temporomandibular joint function in health and disease. See the research recommendations and meeting summary:http://go.usa.gov/DnYT Bill Gates to Present 2013 David E. Barmes Global Health LectureBill Gates, co-chair and trustee of the Bill & Melinda Gates Foundation, will deliver the annual David E. Barmes Global Health Lecture on Monday, October 7th, at 1:00 p.m. in the Masur Auditorium on the NIH campus in Bethesda, MD. The title of his lecture is, "Why the Future Needs Biomedical Innovation." While on the NIH campus, he also will meet with senior leadership, including NIDCR Director Martha Somerman.The Barmes Lecture will be videocast at:http://videocast.nih.govKnown for his philanthropy, Mr. Gates advocates for research and innovation to help people live healthy and productive lives. He also is an outspoken supporter of federal investment in basic science research.In 2000, he and his wife established the Bill & Melinda Gates Foundation to improve international public health through the development of vaccines, therapies, diagnostics, agricultural products, and other technologies. The foundation partners with the private and public sectors to ensure that those technologies can be delivered successfully to the people who need them. In the U.S., the Gates Foundation supports innovations that improve public education. To date, the Gates Foundation has invested $27.6 billion in grants. The David E. Barmes Global Health Lecture Series honors the late David Edward Barmes, special expert for international health at the NIDCR. The lecture series is sponsored by the NIDCR and the Fogarty International Center. Read more:http://go.usa.gov/DVVCRegister Now for "Science and Dentistry in Action: Leading the Way Towards Better Health"NIDCR, the Delta Dental Plans Association, and the Institute for Oral Health are joining forces to bring together top researchers and clinicians for a day of interactive learning and stimulating discussion of current areas of dental science and practice. "Science and Dentistry in Action: Leading the Way Towards Better Health" will take place November 14-15 in Bethesda, Maryland. Be there to learn, share your thoughts, and take home knowledge of how new and exciting developments in science and technology are improving oral health. Program participants will have the opportunity to discuss and explore the scientific rationale/underpinnings of clinical issues commonly encountered in dental practice; identify dental preventive, diagnostic, or treatment modalities for which better evidence and clinical-decision tools could be developed; identify areas requiring more in-depth basic research; and discuss emerging new tools and technologies with the potential to improve dental practice and patient outcomes. Conference participants will receive 5 Continuing Education Credits. To view the agenda and register, go to: http://www.cvent.com/d/w4q79fApplications Accepted for NIDCR Dental Public Health Residency Program NIDCR is accepting applications October 1- December 31, 2013 for its Residency Program in Dental Public Health. The 12-month full-time or 12-month equivalent part-time program provides a formal training opportunity for dentists planning careers in dental public health with an emphasis on oral and craniofacial, health-related epidemiologic research. The Residency Program is accredited by the Commission on Dental Accreditation of the American Dental Association. Program graduates receive a certificate of completion and are qualified educationally to apply for examination by the American Board of Dental Public Health for specialty certification. While emphasizing research training and oral disease prevention and health promotion, the residency also provides experience in other areas of dental public health, i.e. public health administration and management, the organization and financing of dental care programs, and the development of resources. Residents develop an individualized training plan that describes activities to be undertaken during the residency and conduct at least one research project under the guidance of NIDCR staff and other qualified mentors. The application and additional information are found at: http://go.usa.gov/8J4NIH Funds Six Grants to Fund Next Generation Dental CompositeNIDCR has awarded $2.8 million this year for six research projects to pursue a longer-lasting dental composite. The six projects, each funded for five years, will allow a select group of scientists around the country to work independently toward the common goal of doubling the service life of dental composites. In the U.S., dentists currently place more than 122 million dental composites per year. But they fail on average in less than eight years and must be replaced, often with another dental composite. The research projects will team for one of the first times material scientists, polymer chemists, and microbiologists. Another possible area of study will be to characterize whether the natural enzymes in saliva also play a role in degrading restorative dental materials. Read more:http://go.usa.gov/Dv4hDr. Janice Lee Appointed NIDCR Intramural Deputy Clinical DirectorJanice S. Lee, D.D.S., M.D., M.S., is the new Deputy Clinical Director in the Division of Intramural Research at NIDCR. A board-certified oral and maxillofacial surgeon, she comes to NIDCR from the University of California, San Francisco, where she was an associate professor of Clinical Oral and Maxillofacial Surgery in the School of Dentistry. She was promoted to full professor on July 1st. Her extensive research interests include bone regeneration and stem cell biology, craniofacial congenital anomalies, fibrous dysplasia, and McCune-Albright syndrome. Dr. Lee earned her D.D.S. from the UCLA School of Dentistry in 1994, and also received her M.S. there. She then headed to Harvard Medical School, where she earned her M.D. in 1997. Dr. Lee also completed a two-year research fellowship in NIDCR's Craniofacial and Skeletal Diseases Branch.
NIH Commits $24 Million Annually for Big Data Centers of ExcellenceNIH will fund up to $24 million per year for four years to establish six to eight investigator-initiated Big Data to Knowledge Centers of Excellence. The centers will improve the ability of the research community to use increasingly large and complex datasets through the development and distribution of innovative approaches, methods, software, and tools for data sharing, integration, analysis and management. The centers will also provide training for students and researchers to use and develop data science methods. NIH launched the Big Data to Knowledge (BD2K) initiative in December. This initiative supports research, implementation, and training in data science that will enable biomedical scientists to capitalize on the transformative opportunities that large datasets provide. The investigator-initiated BD2K Center of Excellence funding opportunity is the first of several BD2K funding opportunities that will be announced in coming months. Applications are due November 20, 2013. Additional details about the initiative are found at:http://bd2k.nih.govNIH's New Neuroscience Research Center to Open SoonNIH's John Edward Porter Neuroscience Research Center will soon be opening. The building will officially be dedicated on October 21-22 with a ceremony and two-day symposium commemorating the event. NIH, Lacks Family Reach Understanding to Share Genomic Data on HeLa Cells NIH announced in Nature on August 7th that it has reached an understanding with the family of the late Henrietta Lacks to allow biomedical researchers controlled access to the whole genome data of cells derived from her tumor, commonly known as HeLa cells. These cells have already been used extensively in scientific research and have helped make possible some of the most important medical advances of the past 60 years. These include the development of modern vaccines, cancer treatments, in vitro fertilization techniques, and many others.Mrs. Henrietta Lacks, an African-American woman who was 31 at the time of her death, was being treated for cervical cancer at Baltimore’s Johns Hopkins Hospital in 1951. Cells were extracted from the biopsy of her tumor sample for use in research without her knowledge or consent. At the time, there were no federal regulations or restrictions on the use of patients’ cells in research. Although Lacks died shortly afterwards from her aggressive disease, scientists were able to keep her cancer cells alive and replicating under laboratory conditions. The understanding reached with the Lacks family respects their wishes to enable scientific progress while ensuring public acknowledgement of the enormous contribution made by Henrietta Lacks. Read more about the agreement: http://www.nih.gov/news/health/aug2013/nih-07.htmNIH Encourages Institutions to Develop Individual Development Plans for Graduate Students and Postdoctoral ResearchersNIH is encouraging institutions to assist graduate students and postdoctoral researchers (scholars, trainees and fellows, and individuals in other postdoctoral positions) to achieve their career goals within the biomedical research workforce through the use of Individual Development Plans (IDPs). Institutions are encouraged to report on this in all progress reports submitted on or after October 1, 2014, using the Research Performance Progress Report. NIH does not expect institutions to include the actual IDPs; instead the report should outline current practices that document that IDPs are used to help manage the training for graduate students and postdoctoral researchers. See the related Notice:http://grants.nih.gov/grants/guide/notice-files/NOT-OD-13-093.html The recommendation to develop IDPs stems from the Working Group of the Advisory Committee to the NIH Director, which recently completed a study of the future of the biomedical research workforce in the U.S. The working group made recommendations about funding and training of graduate students and postdoctoral researchers to attract and retain the best and most diverse students, engineers and physicians from around the world. A goal of the working group was also to better prepare biomedical graduate students and postdoctoral scientists to successfully participate in a broad-based and evolving economy. Apply Now for the NIH Loan Repayment ProgramsApplications are now being accepted through November 15 for the 2014 NIH Loan Repayment Programs (LRPs). The LRPs encourage outstanding health professionals to pursue careers in biomedical, behavioral, social, and clinical research. In exchange for committing at least two years to conducting qualified research funded by a domestic nonprofit organization or U.S. federal, state, or local government entity, NIH may repay up to $35,000 of qualified student loan debt per year, including most undergraduate, graduate, and medical school loans. Loan repayment benefits are in addition to the institutional salary received for research. The five extramural Loan Repayment Programs include Clinical Research, Pediatric Research, Health Disparities Research, Contraception and Infertility Research, and Clinical Research for Individuals from Disadvantaged Backgrounds. Additional details are found at: http://www.lrp.nih.gov/index.aspxNIH Offers Funding Opportunities for High Risk-High Reward ResearchTo enhance support for high risk-high reward research, the NIH Common Fund offers several unique funding opportunities for scientists with exceptional creativity who propose highly innovative approaches to major contemporary challenges in biomedical research. The following programs are accepting applications: NIH Director's Early Independence Awards (DP5)Early Independence Awards enable exceptional junior scientists to accelerate their entry into an independent research career by forgoing the traditional postdoctoral training period. For these select investigators who have established a record of scientific innovation and research productivity and who have demonstrated unusual leadership, drive, and maturity, postdoctoral training would unnecessarily delay their entry into performing independent research. At the time of application, the Early Independence Award candidate must be within 12 months before or after the completion of their medical residency (or equivalent training). Letters of intent are due by December 31, 2013; applications are due by January 31, 2014. See the announcement:http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-009.html NIH Director's New Innovator Awards (DP2)New Innovator Awards support a small number of early stage investigators who propose highly innovative new research approaches with the potential to produce a major impact on broad, important problems in biomedical and behavioral research. Applications will be accepted from September 25 - October 25, 2013; September 17, 2014 - October 17, 2014; and September 16, 2015 - October 16, 2015. NIH intends to commit approximately $80 million for approximately 33 awards in each of the fiscal years 2014-2016. See the announcement:http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-007.html NIH Pioneer Awards (DP1) Pioneer Awards support individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to addressing major biomedical or behavioral challenges. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator's research program or elsewhere. Applications will be accepted September 18-October 18, 2013; September 10, 2014-October 10, 2014; and September 9, 2015 - October 9, 2015. See the announcement:http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-006.html
Ruth Nowjack-Raymer 301-594-5394
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