News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: February 3, 2014

In this Issue:


NIDCR News

FY 2014 Budget Update
The FY 2014 Omnibus bill contained $398,650,000 for NIDCR. This amount could be reduced for various reasons, including the Secretary's Transfer.

Give Us Your Comments on the NIDCR 2014-2019 Draft Strategic Plan
NIDCR Strategic Plan icon NIDCR has completed drafting its 2014-2019 Strategic Plan. Before finalizing the Strategic Plan, we need the benefit of your comments and observations.

The draft Plan includes four goals and several objectives that provide continuity in key areas while also seizing new research and training opportunities, particularly in harnessing diverse science to enable personalized classification and treatment of dental, oral, and craniofacial health and disease. It also incorporates a series of features that illustrate key examples of NIDCR support and related research opportunities. Our aim is to be responsive to our many constituencies, and to actively advance the breadth, depth, and diversity of dental, oral, and craniofacial research.

Please take time to read the draft and provide your comments to us by Friday, February 7th:
http://go.usa.gov/BCxm

NIDCR Director's Report to the National Advisory Dental and Craniofacial Research Council Provides NIDCR/NIH Snapshot
To learn about NIDCR programmatic news and activities, the budget, recent science advances, and NIH highlights, read the report the NIDCR Director presented at the January 28, 2014 meeting of the National Advisory Dental and Craniofacial Research Council:
http://go.usa.gov/BYJQ

AADR Provides Support to the Foundation for the NIH for a Dental Student in the NIH Medical Research Scholars Young male researcherProgram
The American Association for Dental Research (AADR), together with the Foundation for the National Institutes of Health (FNIH), has announced that AADR will provide $75,000 in funding to support one dental student competitively selected to participate in the 2014-2015 NIH Medical Research Scholars Program (MRSP).

The MRSP is designed to train the most promising future dentists, physicians and veterinarians in research so that they can help resolve clinical problems by understanding their biological underpinnings and, conversely, by translating basic research into clinical interventions. Scholars accepted into the MRSP are provided with a year-long, highly competitive research training experience, designed to inspire research careers. MRSP participants, paired with a dedicated advisor, work within the NIH intramural program for 12-months on a clinical research project or in a basic or translational science laboratory that matches their research interests and career goals. The MRSP provides them with access and exposure to a broad range of exceptional leadership, professional development, scholarship, advocacy, and opportunities for innovation. Additional information about the program is found at:
http://www.cc.nih.gov/training/mrsp/index.html

Personnel Update

  • Dr. Pamela McInnes, Director, Division of Extramural Research, Leaves NIDCR for NCATS Position
    Pamela M. McInnes, DDS, director of NIDCR's Division of Extramural Research (DER) for the past eight years, has left the Institute to become deputy director of the National Center for Advancing Translational Sciences (NCATS). She began her new position earlier this month.

  • Dr. Lillian Shum Appointed Acting Director, Division of Extramural Research
    Lillian Shum, PhD, has been named acting director of the Division of Extramural Research. She joined NIDCR in 2003 as a program director in the Mineralized Tissue Physiology Program and in 2008 was named chief, Integrative Biology and Infectious Diseases Branch. Her work at NIH has been recognized with many honors and awards, including the NIH Director's award. She also is an alumnus of the NIH Executive Leadership Program.

  • Susan Johnson, NIDCR Communications Officer, Retires
    After 30 years with NIDCR and a total of almost 35 years at NIH, NIDCR communications director Susan Johnson retired on January 3rd. Ms. Johnson held a variety of positions at NIDCR. She joined the Institute in 1984 as a science writer and press officer, became chief of the Public Information and Liaison Branch in 1992, and directed the Office of Communications and Health Education (OCHE) since 1999.

  • Karina Boehm Named Acting Director, OCHE
    Karina Boehm, MPH, has been named acting director of NIDCR's Office of Communications and Health Education (OCHE). Ms. Boehm joined NIDCR in 1999 as chief of OCHE's Health Education Branch. In that role she has integrated social marketing and audience research into NIDCR's health communication program, expanded the Institute's multicultural outreach, and established an analytics program to ensure that the Institute's web/digital outreach efforts are user-focused and data-driven.

  • Dr. Margo Adesanya Named Acting Director, Office of Science Policy and Analysis
    Margo Adesanya, DDS, MPH, has been named Acting Director of the Office of Science Policy and Analysis (OSPA). Dr. Adesanya joined OSPA as the Science Planning Officer in 2010 and has been instrumental in supporting the function of that office and the Office of the Director. She has been the lead on several projects to date including directing and facilitating development of fiscal year research initiatives and developing the NIDCR 2014-2019 Strategic Plan.


NIH News

NIH to Fund Research Workforce Diversity Program
NIH recognizes a unique and compelling need to promote diversity in the biomedical, behavioral, clinical, and social sciences research workforce. A key component of NIH's efforts is the establishment of the "Enhancing the Diversity of the NIH-Funded Workforce” program, via the NIH Common Fund. The long-term goal of this program is to catalyze a systematic culture change in the biomedical research training environment to have a broad impact on scientists from underrepresented backgrounds.

Students from underrepresented backgrounds enter early biomedical research training in numbers that reflect the general population but are more likely to exit the training pathways.
Funding through the Enhancing the Diversity of the NIH-Funded Workforce program will establish a national consortium to develop, implement, and evaluate approaches to encourage individuals to start and stay in biomedical research careers. NIH has just released three new funding opportunity announcements (FOAs) to develop approaches to engage researchers, especially from backgrounds underrepresented in biomedical sciences, and prepare them to thrive in NIH-funded research careers:

The National Research Mentoring Network will be a nationwide network of mentors and mentees spanning all disciplines relevant to the NIH mission:
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-017.html

Building Infrastructure Leading to Diversity (BUILD) will provide support for relatively under-resourced institutions with high concentrations of students from disadvantaged backgrounds. It will implement transformative approaches to the training of students to undertake biomedical and behavioral research:
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-016.html

The Coordination and Evaluation Center (CEC) will coordinate consortium-wide activities and assess efficacy of the training and mentoring approaches developed by the BUILD and NRMN awardees:
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-13-015.html

BRAIN Initiative Update
BrainNIH Director Francis S. Collins, M.D., Ph.D., has approved initial areas of high-priority brain research to guide $40 million of NIH fiscal year 2014 funding within the BRAIN (Brain Research through Advancing Innovative Neurotechnologies) Initiative. The initiative aims to accelerate work on technologies that give a dynamic picture of how individual cells and complex neural circuits interact. The ultimate goal is to enhance understanding of the brain and improve prevention, diagnosis, and treatment of brain diseases.

On December 17th, NIH announced six funding opportunities developed in response to high priority areas identified by the NIH Advisory Committee to the Director's BRAIN Working Group in September 2013. Awards are expected to be announced in September 2014. The first wave of NIH investments in the BRAIN initiative will focus largely on technology development that will advance basic science. Two of the funding announcements call for developing methods for classifying and accessing the diverse cells and circuits of the brain. Three focus on developing and optimizing technologies for recording and modulating collections of cells that function together as a circuit. One supports the formation of interdisciplinary teams of scientists to develop the next generation of non-invasive imaging technologies for human research. Additional information about the NIH BRAIN Initiative and the funding opportunities is available at:
http://www.nih.gov/science/brain/

Genomic Data Sharing Policy
Advances in DNA sequencing technologies, as well as a steep drop in sequencing costs, have enabled NIH to fund research that generates a greater volume and wide range of genomic data. In light of these developments, NIH decided to extend the current GWAS Policy to encompass data from a broader spectrum of genomic research. On September 20, 2013, NIH released a draft Genomic Data Sharing Policy (GDS Policy) for public comment. The draft policy applies to all NIH-funded research that involves human and non-human genomic data produced by array-based or high-throughput sequencing technologies, such as GWAS, whole-genome, transcriptomic, epigenomic, and gene expression data, irrespective of the funding level and funding mechanism (i.e., grant, contract, or intramural support).
The public was encouraged to provide comments on any aspect of the draft GDS Policy through November 20, 2013. The draft policy is found in the Federal Register notice:
http://go.usa.gov/Bauz

NIH Announces Plan to Increase Funding Toward a Cure for Red AIDS ribbonHIV/AIDS
At a White House event held December 2nd to mark the 25th annual World AIDS Day, President Obama announced that the NIH plans to redirect AIDS research funds to expand support for research directed toward a cure for HIV. NIH plans to invest an additional $100 million over the next three fiscal years on this increasingly promising area of HIV/AIDS research.

It is anticipated that a significant portion of the new investment will support basic research. These studies will include research on viral reservoirs, viral latency, and viral persistence, as well as studies of neutralizing antibodies. Research on animal models, drug development and preclinical testing of more potent antiretroviral compounds capable of diminishing viral reservoirs, and clinical research, such as studies on therapeutic vaccines and other immune enhancers, also will be included.

NIH Featured on C-SPAN's Washington Journal
C-SPAN's Washington Journal hosted its full 3-hour show on the National Institutes of Health (NIH) campus on Friday, December 6, 2013. Host Steve Scully spoke with NIH Director Francis S. Collins, M.D., Ph.D., and several of the NIH institute and center directors about the impact of reductions to the NIH budget on cancer, HIV/AIDS, genomics and mental health research. Viewers were able to call in and ask questions. View each Director's segment at:
http://www.c-spanvideo.org/event/228147

Dr. Hannah Valantine Selected as Chief Officer for Scientific Hannah Valantine, M.D.Workforce Diversity
Following a nationwide search, Dr. Collins has appointed Hannah Valantine, M.D., to the permanent position of Chief Officer for Scientific Workforce Diversity. Dr. Valantine will lead NIH's effort to diversify the biomedical research workforce by developing a vision and comprehensive strategy to expand recruitment and retention, and promote inclusiveness and equity throughout the biomedical research enterprise. Dr. Valantine is expected to begin her new role this spring. Her appointment stems from a recommendation by the Biomedical Research Workforce Diversity Working Group of the Advisory Committee to the Director (ACD) that called for a newly created position entirely dedicated to diversity. Dr. Valantine will work closely with the NIH institutes and centers, NIH grantee community, and community stakeholders to ensure engagement on the issue at all levels.

Dr. Valantine comes to the NIH from Stanford University where she served as Senior Associate Dean for Diversity and Leadership at Stanford School of Medicine, and Professor of Cardiovascular Medicine at Stanford University Medical Center. In addition to a prestigious career in cardiology, Dr. Valantine is a past recipient of the NIH Director's Pathfinder Award for Diversity in the Scientific Workforce and has a proven record on implementing diversity initiatives in academic medicine.

Dr. Philip Bourne Named Associate Director for Data Science
Philip Bourne, Ph.D.Philip E. Bourne, Ph.D., has been named the new Associate Director for Data Science, Office of the Director. Dr. Collins had announced recruitment last year for this new senior scientific position to lead an NIH-wide priority initiative to take better advantage of the exponential growth of biomedical research datasets, which is an area of critical importance to biomedical research. In the era of “Big Data,” it is vital that NIH play a major role in coordinating access to, and analysis of, the many different data types that make up this revolution in biological information.

Dr. Bourne comes to the NIH from the University of California, San Diego, where he is the Associate Vice Chancellor for Innovation and Industry Alliances of the Office of Research Affairs. He also is a professor in the Department of Pharmacology and the Skaggs School of Pharmacy and Pharmaceutical Sciences and the Associate Director of the Research Collaboratory for Structural Bioinformatics (RCSB) Protein Data Bank.


SCIENCE ADVANCES



Cells That Break Down Collagen

Fluorescent collagen internalized into the skin cells of a mouseNIDCR scientists are surprised to discover that M2-like macrophages are important for collagen internalization and degradation. Read more:http://go.usa.gov/Bgce








Targeting HPV-Transformed Cells

Human papillomavirus (HPV)Researchers discovers molecules apt to enter tonsil cells as an emerging therapeutic strategy for HPV-transformed oral cancer cells. Read more:
http://go.usa.gov/BYhG







Periodontitis: Balancing Nature's Immune Response

Steven R. Little, Ph.D.Treating periodontitis typically involves removing infection-causing oral microbes. But it is inflammation that causes severe tissue damage. Researchers report a fascinating first step in treating periodontal disease by inducing a more-balanced immune response. Read the interview with Steven R. Little, Ph.D., senior author on the paper and an NIDCR grantee:
http://go.usa.gov/BgqR





FUNDING OPPORTUNITY NEWS

PROGRAM ANNOUNCEMENTS

Cancer
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Specialized Programs of Research Excellence (SPOREs) in Human Cancer for Year 2014 (P50) 12/11/13 PAR-14-031

Sundar Venkatachalam
301-594-4812

9/24/14
Career Development
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
NIDCR Dentist Scientist Pathway to Independence Award (K99/R00) 1/02/14 PAR-14-057 Leslie Frieden
301-496-4263
1/08/17
NIH Pathway to Independence Award (Parent K99/R00) 12/19/13 PA-14-042 Leslie Frieden
301-496-4263
1/08/17
Short-term Mentored Career Enhancement Award in Dental, Oral and Craniofacial Research for Mid-Career and Senior Investigators (K18) 12/13/13 PAR-14-039 Lynn Mertens King
301-594-5006

Dave Clark
301-594-4814

Emily Harris
301-594-4846
2/13/17
Independent Scientist Award (Parent K02) 12/19/13 PA-14-045 Lynn Mertens King
301-594-5006
1/08/17
Mentored Clinical Scientist Research Career Development Award (Parent K08) 12/19/13 PA-14-046 Lynn Mertens King
301-594-5006
1/08/17
Mentored Patient-Oriented Research Career Development Award (Parent K23) 12/19/13 PA-14-049 Lynn Mertens King
301-594-5006
1/08/17
Mentored Quantitative Research Development Award (Parent K25) 12/19/13 PA-14-048 Lynn Mertens King
301-594-5006
1/08/17
Gene Studies
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Genetic Susceptibility & Variability of Human Structural Birth Defects (R01) 1/02/14 PA-14-056 Steven Scholnick
301-594-3977
1/08/17
Neurobiology/Pain
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Neurobiology of Migraine (R21) 1/13/14 PA-14-069 John Kusiak
301-594-7984
5/08/17
Neurobiology of Migraine (R01) 1/13/14 PA-14-068 John Kusiak
301-594-7984
5/08/17
Research Mechanisms
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
PHS 2014-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]) 1/17/14 PA-14-072 R. Dwayne Lunsford
301-594-2421
1/08/15
PHS 2014-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) 1/17/14 PA-14-071 R. Dwayne Lunsford
301-594-2421
1/08/15
Research Supplements
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Administrative Supplements for Research on Sex/Gender Differences (Admin Supp) 12/11/13 PA-14-027 Jane Atkinson
301-435-7098
2/07/14
Small Business
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
PHS 2014-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42]) 1/17/14 PA-14-072 R. Dwayne Lunsford
301-594-2421
1/08/15
PHS 2014-02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44]) 1/17/14 PA-14-071 R. Dwayne Lunsford
301-594-2421
1/08/15
REQUESTS FOR APPLICATIONS
Career Development
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Mentored Career Development Award in Biomedical Big Data Science for Clinicians and Doctorally Prepared Scientists (K01) 1/15/14 RFA-HG-14-007 Lynn Mertens King
301-594-5006
4/01/14;4/01/15
Computational Science
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Computational Analyses Exploiting Reference Epigenomic Maps (R01) 12/10/13 RFA-RM-14-001 Lillian Shum
301-594-0618
3/03/14
BD2K-LINCS-Perturbation Data Coordination and Integration Center (DCIC) (U54) 12/04/13 RFA-HG-14-001 Steven Scholnick
301-594-3977
3/19/14
Neurobiology/Pain
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
BRAIN Initiative: Transformative Approaches for Cell-Type Classification in the Brain (U01) 12/17/13 RFA-MH-14-215 John Kusiak
301-594-7984
3/13/14
BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (U01) 12/17/13 RFA-MH-14-216 John Kusiak
301-594-7984
3/13/14
BRAIN Initiative: Planning for Next Generation Human Brain Imaging (R24) 12/17/13 RFA-MH-14-217 John Kusiak
301-594-7984
3/13/14
Brain Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (U01) 12/17/13 RFA-NS-14-007 John Kusiak
301-594-7984
3/24/14
BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01) 12/17/13 RFA-NS-14-008 John Kusiak
301-594-7984
3/24/14
BRAIN Initiative: Integrated Approaches to Understanding Circuit Function in the Nervous System (U01) 12/17/13 RFA-NS-14-009 John Kusiak
301-594-7984
3/24/14
NIH Research Initiatives
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
NIH Director's Biomedical Research Workforce Innovation Award: Broadening Experiences in Scientific Training (BEST) (DP7) 1/17/14 RFA-RM-13-019 Lynn Mertens King
301-594-5006

3/31/14
NIH National Research Mentoring Network (NRMN) (U54) 12/19/13 RFA-RM-13-017 Lynn Mertens King
301-594-5006
4/02/14
NIH Building Infrastructure Leading to Diversity (BUILD) Initiative (U54) 12/19/13 RFA-RM-13-016 Lynn Mertens King
301-594-5006
4/02/14
NIH Coordination and Evaluation Center for Enhancing the Diversity of the NIH-Funded Workforce Program (U54) 12/19/13 RFA-RM-13-015 Lynn Mertens King
301-594-5006
4/02/14
Validation and Advanced Development of Technologies for the Study of Biological Properties of Single Cells (R33) 12/19/13 RFA-RM-13-020 Lillian Shum
301-594-0618
4/04/14
Exceptionally Innovative Tools and Technologies for Single Cell Analysis (R21) 12/19/13 RFA-RM-13-021 Lillian Shum
301-594-0618
4/04/14
Revisions to Add Single Cell Analysis to Active Research Projects (R01) 12/19/13 RFA-RM-13-022 Lillian Shum
301-594-0618
4/04/14
Revisions to Add Single Cell Analysis to Active Research Projects (U01) 12/19/13 RFA-RM-13-023 Lillian Shum
301-594-0618
4/04/14
Training
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Courses for Skills Development in Biomedical Big Data Science (R25) 1/16/14 RFA-HG-14-008 Lynn Mertens King
301-594-5006

4/01/14; 4/01/15; 4/01/16
Open Educational Resources for Biomedical Big Data (R25) 1/16/14 RFA-HG-14-009 Lynn Mertens King
301-594-5006

4/01/14; 4/01/15; 4/01/16

NOTICES

Title NIH
Guide
Notice Number
Notice of Change to Application Due Date for RFA-RM-13-015 "NIH Coordination and Evaluation Center (CEC) (U54)" 1/10/14 NOT-RM-14-005
Notice of Change to Application Due Date for RFA-RM-13-017 "NIH National Research Mentoring Network (NRMN) (U54)" 1/10/14 NOT-RM-14-004
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PAR-14-031 "Specialized Programs of Research Excellence (SPOREs) in Human Cancer for Year 2014 (P50)" 12/20/13 NOT-DE-14-002
Notice of Reissuance of the Parent Research Development (K) Award Funding Opportunity Announcements 12/18/13 NOT-OD-14-036
Notice of Extension of Expiration Date for PA-11-181 "Research on Ethical Issues in Biomedical, Social and Behavioral Research (R03)" 12/13/13 NOT-OD-14-032
Notice of Extension of Expiration Date for PA-11-182 "Research on Ethical Issues in Biomedical, Social and Behavioral Research (R21)" 12/13/13 NOT-OD-14-033
Change in the NIH Continuous Submission Policy 12/04/13 NOT-OD-14-028
NIH Reminds Applicants to Use Updated Electronic Application Forms (FORMS-C) for F, K, T and D Submissions with Due Dates on/after January 25, 2014 11/27/13 NOT-OD-14-027
NIH Will Require Use of Research Performance Progress Report (RPPR) for All Multi-Year Funded Awards 11/25/13 NOT-OD-14-026
Update to the Interim Agency Policy, NIH Extramural and Intramural Research Involving Chimpanzees 11/25/13 NOT-OD-14-024

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​​

National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

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