News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: December 20, 2012

In this Issue:

 


 

NIDCR News

The Wellcome Trust Director Sir Mark Walport to Deliver David E. Barmes Global Health Sir Mark Walport, FRS, FMedSciLecture
Sir Mark Walport, FRS, FMedSci, Director of The Wellcome Trust and UK Chief Science Adviser appointee, will present the annual David E. Barmes Global Health Lecture on Wednesday, January 30, 2013, from 11 a.m. - 12 p.m. in the Masur Auditorium (Building 10) on the NIH campus in Bethesda, MD.  The title of his lecture is "Global Health: From John Snow to Genome Science."  The lecture is jointly sponsored by the Fogarty International Center and the NIDCR.  As head of The Wellcome Trust, Sir Walport oversees one of the largest global charitable foundations supporting biomedical research. The Wellcome Trust is also the UK's largest non-governmental source of funds for biomedical research. In April 2013, he will begin his new position as the UK Chief Scientific Adviser.     

Additional information about Sir Walport is found at:
http://www.wellcome.ac.uk/About-us/Organisation/Governance/Executive-Board/index.htm

The David E. Barmes Global Health Lecture Series honors the late David Edward Barmes, special expert for international health at the NIDCR.  Prior to joining the NIDCR, Dr. Barmes, a public health dentist and epidemiologist by training, served in senior management positions related to oral health, health promotion, and non-communicable diseases at the World Health Organization in Geneva.  The lecture series is sponsored by NIDCR and the Fogarty  International Center to honor his lifelong dedication to research aimed at improving health for those in low-income countries.

The Barmes Lecture will be videocast at:
http://videocast.nih.gov

FY 2013 Extramural Funding Plan
The NIH is currently operating under a Continuing Resolution (CR) which allows NIDCR to operate through March 27, 2013 at a budget level approximating the FY 2012 level.  Until the FY 2013 appropriation is finalized, NIDCR will issue non-competing research grant awards at a level below that indicated on the most recent Notice of Award (up to 90% of the previously committed level).  See the complete notice published in the NIH Guide:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-13-002.html 

Applications Accepted for 2013 NIDCR Summer Dental Student Award
Male and female 2012 Summer Dental Student Awardees To expose future dentists to careers in research, NIDCR offers an outstanding summer training opportunity in its intramural research labs for dental students.  The NIDCR Summer Dental Student Award is designed to give talented dental students hands-on research experience and exposure to the latest advances in oral health research.  Selected candidates are assigned to mentors who conduct research in the students’ areas of interest.  Participation in the program may result in presentation of research findings at a scientific meeting or co-authorship of scientific publications.

The NIDCR provides a competitive stipend for all summer researchers.  Acceptance of this reward requires a minimum eight-week commitment.  The nominating dental school must agree to support air or ground transportation for their students.  Although housing is not supplied by NIDCR, student housing resource guides are provided.

NIDCR is accepting online applications for the Summer Dental Student Award until January 17, 2013.    All supplemental application information must be received by February 8, 2013. For additional information on how to apply, please visit:
http://go.usa.gov/gm7h
or contact Dr. Deborah Philp, Program Director, dphilp@mail.nih.gov , (301) 594-6578 

 


 

NIH News

NIH Proposes Critical Initiatives to Sustain Future of U.S. Biomedical Research
A summary of the actions that NIH is seeking to implement regarding Diversity in the Biomedical Research Workforce, the Future Biomedical Research Workforce, and Data and Informatics is found at:
http://www.nih.gov/news/health/dec2012/od-07.htm
NIH is seeking to launch multiple initiatives designed to help strengthen the biomedical research enterprise and sustain the global competitiveness of the U.S. scientific community well into the future.  Faced with significant challenges affecting the biomedical research workforce and the storage and use of large biomedical datasets, the NIH Director charged the Advisory Committee to the Director (ACD) to develop recommendations.  The ACD used three specialized committee working groups, each of which included additional outside experts on the relevant topics.  The ACD presented its recommendations to the NIH Director in June 2012.  NIH leadership further deliberated on the recommendations and presented its implementation plan at the 105th meeting of the ACD on December 6-7.  

Meeting of Interagency Pain Research Coordinating Committee
The second meeting of the Interagency Pain Research Coordinating Committee (IPRCC) took place October 22 and focused largely on developing a summary of pain research advances and assessing an IPRCC analysis of the federal pain research portfolio. The ultimate goal is to identify critical gaps in federally-funded pain research, make recommendations on how to prevent duplication of effort, and capitalize on opportunities for collaboration. NIDCR Director Martha J. Somerman serves as a member of the IPRCC. Dr. Story Landis, Director of the National Institute of Neurological Disorders and Stroke (NINDS), serves as chair of the committee. NIH recently named Dr. Linda Porter, a program director in the NINDS Division of Extramural Research, to be the Designated Federal Official for the Interagency Pain Research Coordinating Committee.  Information about this committee, as well as the meeting agenda and materials, can be found on the committee website:
http://iprcc.nih.gov/index.htm
The videocast of the full meeting is available at:
http://videocast.nih.gov/PastEvents.asp?c=200

NIH Director's New Blog and Twitter Account
Francis S. Collins, M.D. Ph.D.NIH Director Francis S. Collins has established a Director's blog and Twitter account, reflecting the importance he places on communicating the value of biomedical research and telling the NIH story through all forms of media.  Visit the Director's blog at:
http://directorsblog.nih.gov/ 
The Twitter account is found at:
http://twitter.com/NIHDirector






NIH Names Dr. Richard Nakamura as Director of the Center for Scientific Review
Richard Nakamura, Ph.D.Dr. Collins has announced the selection of Richard Nakamura, Ph.D., as the new director of the NIH Center for Scientific Review.  Dr. Nakamura had been serving as the acting director since September 2011.  He leads CSR's 450 scientists and administrative staff, overseeing their efforts to manage 80,000 incoming NIH grant applications a year and review the majority of them in CSR peer review groups. Prior to joining the Center for Scientific Review, Dr. Nakamura had a 32-year career at the National Institute of Mental Health (NIMH), where he served as both its Scientific Director and Deputy Director.  He also was Acting Director of the NIMH from 2001 to 2002. 



Public Access Policy and Compliance Changes  - Spring 2013
The NIH announced that in Spring 2013, NIH will delay processing of non-competing continuation grant awards if publications arising from that award are not in compliance with the NIH public access policy.  This change will take effect in conjunction with NIH requiring the use of the Research Performance Progress Report (RPPRs) for all Streamlined Non-competing Award Process (SNAP) and Fellowship awards in the Spring.  For more on the new requirements and available resources, see NIH Guide Notice NOT-OD-12-160:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-12-160.html

NIH Funds Will Strengthen National Capacity for Cost-Effective, Large-Scale Clinical Studies
Funds totaling approximately $11.3 million will support the first year of the Health Care Systems (HCS) Research Collaboratory, which will engage health care systems as research partners in conducting large-scale clinical studies.  The funds are managed through the NIH Common Fund.

Health care systems, which include health maintenance organizations and other large integrated care settings, see large populations of patients.  By partnering with these entities, NIH will be able to conduct large-scale and more cost-effective clinical research within the settings where patients are already receiving their care.  The eight awards funded as part of the collaboratory include the HCS Research Collaboratory Coordinating Center (Duke University, Durham, NC) and the following seven pragmatic clinical trial demonstration projects: Decreasing Bioburden to Reduce Health Care-Associated Infections and Readmissions, University of California, Irvine; Strategies and Opportunities to Stop Colon Cancer in Priority Populations, Kaiser Foundation Hospitals, Portland, OR; Pragmatic Trial of Population-based Programs to Prevent Suicide Attempt, Group Health Cooperative, Seattle; A Pragmatic Trial of Lumbar Image Reporting with Epidemiology (LIRE), University of Washington, Seattle; Nighttime Dosing of Anti-Hypertensive Medications: A Pragmatic Clinical Trial, University of Iowa, Iowa City; Collaborative Care for Chronic Pain in Primary Care, Kaiser Foundation Hospitals, Portland, OR; Pragmatic Trials in Maintenance Hemodialysis, University of Pennsylvania, Philadelphia, PA.

2012 NIH Director’s Early Independence Awards Recognizes 14 Scientists
Fourteen exceptional junior scientists, who were within one year of completing their doctoral degrees or clinical residencies at the time of application, will be supported by the NIH Director's Early Independence award. The program encourages young scientists who have demonstrated outstanding scientific creativity, intellectual maturity, and leadership skills with the opportunity to conduct independent biomedical or behavioral research by skipping the conventional post-doctoral training period. The NIH Common Fund and contributing NIH institutes plan to commit potentially $25.9 million to support these research projects over five years, contingent on the availability of funds.  Read more about the awardees:
http://www.nih.gov/news/health/oct2012/od-01.htm

NIH Grantees Win 2012 Nobel Prize in Chemistry
The 2012 Nobel Prize in chemistry has been awarded to NIH grantees Robert J. Lefkowitz, M.D., of the Howard Hughes Medical Institute and Duke University Medical Center, Durham, N.C.; and Brian K. Kobilka, M.D., of the Stanford University School of Medicine, Stanford, Calif., for studies of protein receptors that let body cells sense and respond to outside signals.

The Royal Swedish Academy of Sciences said the researchers had made groundbreaking discoveries on an important family of receptors known as G-protein-coupled receptors.


SCIENCE ADVANCES

First Gene Therapy Study in Human Salivary Gland Shows Promise
Bruce Baum, D.M.D., Ph.D. Gene therapy can be performed safely in the human salivary gland, according to scientists at the NIDCR.  The finding comes from the first-ever safety, or Phase I, clinical study of gene therapy in a human salivary gland.  Its results, published in the Proceedings of the National Academy of Sciences, also show that the transferred gene, Aquaporin-1, has great potential to help head and neck cancer survivors who battle with chronic dry mouth.  Aquaporin-1 encodes a protein that naturally forms pore-like water channels in the membranes of cells to help move fluid, such as occurs when salivary gland cells secrete saliva into the mouth.  Bruce Baum, D.M.D., Ph.D., recently retired NIDCR scientist, is the lead author on the study.  Read more: 
   http://go.usa.gov/gm6w

FUNDING OPPORTUNITY NEWS

PROGRAM ANNOUNCEMENTS

Gene Studies
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
NIDCR Small Research Grants for Data Analysis and Statistical Methodology Applied to Genome-wide Data (R03) 12/14/12 PAR-13-044 Emily Harris
301-594-4846
1/08/16
NIH Roadmap Initiatives
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Collaborative Activities to Promote Metabolomics Research (Admin Supp) 12/13/12 PA-13-041 Lillian Shum
301-594-0618
3/16/13
Research Supplements
Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Collaborative Activities to Promote Metabolomics Research (Admin Supp) 12/13/12 PA-13-041 Lillian Shum
301-594-0618
3/16/13
Administrative Supplements for Research on Sex/Gender Differences (Admin Supp) 11/13/12 PA-13-018 Jane Atkinson
301-435-7908
1/12/13


REQUESTS FOR APPLICATIONS

AIDS
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Epigenomics of Virus-Associated Oral Diseases (R01) 10/31/12 RFA-DE-13-002 Isaac Rodriguez-Chavez
301-594-7985
2/21/13
Epigenomics of Virus-Associated Oral Diseases (R21) 10/31/12 RFA-DE-13-003 Isaac Rodriguez-Chavez
301-594-7985
2/21/13
Behavioral/Social Research
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Determinants and Consequences of Personalized Health Care and Prevention (U01) 11/21/12 RFA-RM-12-024 David Clark
301-594-4814
2/28/13
NIH Roadmap
Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Evaluation of Multi-'omic Data in Understanding the Human Microbiome's Role in Health and Disease (U54) 11/30/12 RFA-RM-12-021 R. Dwayne Lunsford
301-594-2421
2/08/13
Determinants and Consequences of Personalized Health Care and Prevention (U01) 11/21/12 RFA-RM-12-024 David Clark
301-594-4814
2/28/13

 NOTICES

Title NIH
Guide
Notice Number
Advance Notice: Revised Policy for Managing Conflict of Interest in the Initial Peer Review of NIH Grant and Cooperative Agreement Applications 11/30/12 NOT-OD-13-010
Upcoming Changes to Public Access Policy Reporting Requirements and Related NIH Efforts to Enhance Compliance 11/16/12 NOT-OD-12-160
NIH Provides Policy Clarification Concerning Disclosure Requirements for Reimbursed and Sponsored Travel - 42 CFR Part 50 Subpart F, "Responsibility of Applicants for Promoting Objectivity in Research for Which PHS Funding is Sought" 10/18/12 NOT-OD-13-004
NIH Operates Under a Continuing Resolution 10/11/12 NOT-OD-13-002

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Thank you.


National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

Department of Health and Human Services (HHS)   National Institutes of Health (NIH)   USA.gov