News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: April 8, 2011

In this Issue:
1. NIDCR News
2. NIH News
3. Science Advances
4. Funding Opportunity News


NIDCR News

NIDCR Supplement to the Journal of Public Health Dentistry
Journal of Public Health DentistryNIDCR is pleased to announce the publication of the NIDCR Supplement to the Journal of Public Health Dentistry on behavioral and social intervention research essentials. The issue highlights several important areas that are crucial to high quality behavioral and social intervention research. It is our hope that readers will find this to be a valuable tool in developing research proposals, enhancing existing intervention research studies, and making today’s intervention studies more informative for the next generation of research.

Articles highlight:
--PRECEDE-PROCEED and the importance of using intervention planning models
--The role of health behavior theory in developing interventions
--Mediators, moderators, and testing for mechanisms of action
--The importance of fidelity adherence and monitoring in different stages of research
--Determining feasibility and acceptability of interventions to the target populations
--Studying the sustainability of interventions as part of a larger program of research
--Assessing intervention sustainability through cost-utility and economic analyses

Each manuscript is followed by brief commentary from additional experts in the field. Access to this supplement is free for the first year of publication. To view the special journal issue, please visit the Wiley website:
http://onlinelibrary.wiley.com/doi/10.1111/jphd.2011.71.issue-s1/issuetoc.


NIDCR Launches New Homepage
New NIDCR homepageThe NIDCR homepage has a new look. This updated version provides faster access to science news, researcher interviews, funding opportunities, and popular oral health publications. Additional features include fly-out menus in the top navigation to help users quickly accomplish key tasks, an image gallery, and a toolbar that highlights NIDCR's social media presence. The A-Z index is also higher up on the page where visitors can more readily find it. Visit the new homepage at http://www.nidcr.nih.gov/.


NIH News

New Strategic Plan for NIH Obesity Research Seeks to Curb Epidemic
The Strategic Plan for NIH Obesity ResearchTo combat the obesity epidemic, NIH is encouraging diverse scientific investigations through a new Strategic Plan for NIH Obesity Research. More than one-third of adults in the U.S. and nearly 17 percent of the nation’s children are now obese, which increases a person’s chance of developing many health problems, including type 2 diabetes, heart disease, high blood pressure, fatty liver disease, and some cancers.

NIH funds research to reduce the prevalence of obesity and its health consequences (an investment of $824 million in fiscal year 2010, plus awards totaling $147 million made in the same year through the Recovery Act). The NIH strategic plan, developed by the NIH Obesity Research Task Force, recognizes that eating less and exercising more is easier said than done. Highlighting the crucial role of research in efforts to reduce obesity, the plan emphasizes moving science from laboratory to clinical trials to practical solutions, and is designed to help target efforts and resources in areas most likely to help. See more about the strategic plan:
http://www.obesityresearch.nih.gov/About/strategic-plan.htm


NIH Launches Largest Oil Spill Health Study:
Gulf Study workers on the beach collecting samplesGuLF STUDY to follow 55,000 cleanup workers and volunteers for up to 10 years
A new study that will look at possible health effects of the Gulf of Mexico’s Deepwater Horizon oil spill on 55,000 cleanup workers and volunteers has begun in towns across Louisiana, Mississippi, Alabama, and Florida.

The GuLF STUDY (Gulf Long-term Follow-up Study) is the largest health study of its kind ever conducted among cleanup workers and volunteers, and is one component of a comprehensive federal response to the Deepwater Horizon oil spill. The study is being conducted by the National Institute of Environmental Health Sciences, part of the NIH, and is expected to last up to 10 years. Over time, the GuLF STUDY will generate important data that may help inform policy decisions on health care and health services in the region. For additional information visit the GuLF STUDY website at:
http://www.niehs.nih.gov/about/od/programs/gulfspill/gulfstudy/index.cfm.


New Robot System to Test 10,000 Chemicals for Toxicity
robotSeveral federal agencies, including the NIH, have unveiled a new high-speed robot screening system--called Tox21--that will test 10,000 different chemicals for potential toxicity. The chemicals to be screened include compounds found in industrial and consumer products, food additives, and drugs. Tox21 is located at the NIH Chemical Genomics Center in Rockville, MD, and merges existing agency resources (research, funding, and testing tools) to develop ways to more effectively predict how chemicals will affect human health and the environment. The system marks the beginning of a new phase of an ongoing collaboration that is working to protect human health by improving how chemicals are tested in the U.S.

Tox21 is a collaborative effort among the National Institute of Environmental Health Sciences, the National Toxicology Program, the National Human Genome Research Institute, the U.S. Environmental Protection Agency, and the U.S. Food and Drug Administration. See more about the system:
http://www.genome.gov/27543670.


Training Institute on Dissemination and Implementation Research
Training Institute for Dissemination and Implementation Research in Health icon On August 1-5, 2011, NIH will hold a five-day training session on dissemination and implementation health research. One of the most critical issues impeding improvements in public health today is the enormous gap between the best evidence-based strategies to improve health and what actually gets used and implemented in everyday practice. The science of dissemination and implementation seeks to address this gap by understanding how to best ensure that evidence-based strategies to improve health and prevent disease are effectively delivered in clinical and public health practice.

The Training Institute for Dissemination and Implementation Research in Health will feature a faculty of leading experts from a variety of behavioral and social science disciplines. The University of North Carolina at Chapel Hill’s Center for Health Promotion and Disease Prevention will host the institute at its Rizzo Conference Center in Chapel Hill, NC. Applications are being accepted through April 15, 2011. To register and for more information, please visit:
http://conferences.thehillgroup.com/OBSSRinstitutes/TIDIRH2011/index.html


Summer Institute on mHealth
mHealth Research iconNIH has announced the creation of the first NIH mHealth, or mobile health, Summer Institute. Scheduled for the summer of 2011, this week-long workshop will bring together leaders in mobile health technologies, behavioral science researchers, federal health officials and members of the medical community to provide early career investigators with an opportunity to learn about mHealth research.

Mobile technologies have the potential to transform medical research and enable health care providers to more rapidly and accurately assess biological processes, behavior, attitudes, and the environment. These technologies also allow providers to help patients improve their health in real time—enabling them to personalize health care options and monitor progress. NIH’s mHealth Summer Institute will provide an overview of the engineering, behavioral science and clinical aspects of wireless research.
[Please note: Applications are no longer being accepted for the 2011 institute]:
http://obssr.od.nih.gov/training_and_education/mhealth/index.aspx


Dr. Rajesh Ranganathan Appointed Senior Advisor for Translational Research
Rajesh Ranganathan, Ph.D.NIH Director Francis S. Collins has announced the appointment of Rajesh Ranganathan, Ph.D., as senior advisor for translational research. Dr. Ranganathan will provide leadership and expertise in planning and establishing NIH-wide program priorities that focus on accelerating the translation of scientific discoveries from the bench to the bedside. He comes to the NIH from Novartis Institutes for Biomedical Research Inc., where he was the global head of the Scientific Education Office and a director in the Scientific Portfolio Management and Strategy Office.


SCIENCE ADVANCES

A Rare Find
Katiuchia Uzzun Sales, D.D.S., Ph.D.A rare disease and a unique research opportunity. Read how an NIDCR postdoc took the rash out of an experimental model for Netherton syndrome.
http://go.usa.gov/T3P

Flipping the Switch
Murine SCCs resemble human SCCTargeted therapy is a buzzword in oncology. It's also fast becoming a clinical reality. Read about a newly identified target with implications for a common oral cancer.

A Few Discoveries Away
Salivary glandResearchers discover salivary glands can act as an alternative mucosal route to administer vaccines.

Detecting Early Tooth Decay
PLM image of the occlusal surfaceThe first step to avoid drilling and filling a tooth is to catch decay early. Scientists show for the first time that a promising imaging technique can do just that.

Except by Stealth
Orf63 is a viral homolog and inhibitor of NLRP1Kaposi's sarcoma-associated herpesviruses are a study in stealth. Researchers discover one of its essential secret weapons.

Challenging Innate Immunity
Structure of Kly18A hard-to-study oral bacterium has now entered the genomic era. The evolutionary tales written into some of its genes are surprising scientists.


FUNDING OPPORTUNITY NEWS


PROGRAM ANNOUNCEMENTS

Behavioral/Social Research

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Research on Ethical Issues in Biomedical, Social, and Behavioral Research (R21) 3/24/11 PA-11-182 Jane Atkinson
301-435-7908
5/08/14
Research on Ethical Issues in Biomedical, Social, and Behavioral Research (R03) 3/24/11 PA-11-181 Jane Atkinson
301-435-7908
5/08/14


Biotechnology/Regenerative Medicine/Biomaterials

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Nanoscience and Nanotechnology in Biology and Medicine (R21) 3/14/11 PA-11-149 Nadya Lumelsky 
301-594-7703
5/08/14
Nanoscience and Nanotechnology in Biology and Medicine (R01) 3/14/11 PA-11-148 Nadya Lumelsky 
301-594-7703
5/08/14


Cancer

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Biomarkers of Infection-Associated Cancers (R21) 3/17/11 PA-11-159 Lillian Shum
301-594-0618
5/08/14
Biomarkers of Infection-Associated Cancers (R01) 3/17/11 PA-11-158 Lillian Shum
301-594-0618
5/08/14


Fellowships

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral MD/PhD and Other Dual Doctoral Degree Fellows (Parent F30) 2/10/11 PA-11-110 Leslie Frieden
301-496-4263
5/08/14
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows (Parent F31) 2/10/11 PA-11-111 Leslie Frieden
301-496-4263
5/08/14
Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows to Promote Diversity in Health-Related Research (Parent F31 - Diversity) 2/10/11 PA-11-112 Leslie Frieden
301-496-4263
5/08/14
Ruth L. Kirschstein National Research Service Awards for Individual Postdoctoral Fellows (Parent F32) 2/10/11 PA-11-113 Leslie Frieden
301-496-4263
5/08/14
Ruth L. Kirschstein National Research Service Awards for Individual Senior Fellows (Parent F33) 2/10/11 PA-11-114 Leslie Frieden
301-496-4263
5/08/14


Gene Studies

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Genetic Screens to Enhance Zebrafish Research (R01) 3/30/11 PAR-11-130 Steven Scholnick
301-594-3977
9/20/13
Enhancing Zebrafish Research with Research Tools and Techniques (R01) 3/30/11 PAR-11-131 Steven Scholnick
301-594-3977
9/20/13


Research Supplements

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Competitive Revision Applications for NIDCR-funded Cooperative Agreements (U01) 3/11/11 PAR-11-144 Steven Scholnick
301-594-3977
1/08/14



REQUESTS FOR APPLICATIONS

Neurobiology/Pain

Title NIH
Guide
RFA 
Number
NIDCR Contact Application Receipt Date
NIH Blueprint for Neuroscience Research Grand Challenge: Developing Novel Drugs for Disorders of the Nervous System (U01) 3/16/11 RFA-NS-12-002 John Kusiak
301-594-7984
6/10/11 and 12/15/11
Blueprint for Neuroscience Research Science Education Award (R25) 2/10/11 RFA-DA-11-013 John Kusiak
301-594-7984
4/11/11


NIH Roadmap

Title NIH
Guide
RFA 
Number
NIDCR Contact Application Receipt Date
NIH-HMO Collaboratory Coordinating Center Limited Competition (U54) 2/17/11 RFA-RM-11-003 Jane Atkinson
301-435-7908
5/27/11


Training

Title NIH
Guide
RFA 
Number
NIDCR Contact Application Receipt Date
NLM Institutional Training Grants for Research Training in Biomedical Informatics (T-15)  2/28/11 RFA-LM-11-001 Kevin Hardwick
301-594-2765
4/28/11



NOTICES

Title NIH
Guide
Notice Number
Clarification of Instructions in Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows: PA-11-110, PA-11-111, and PA-11-112 4/01/11 NOT-OD-11-062
Cancellation of the Remaining Receipt Dates for PAR-09-027 3/31/11 NOT-RM-11-013
Registration Now Open for Upcoming NIH Grants Seminars in Scottsdale, AZ and Ft. Lauderdale, FL 3/31/11 NOT-OD-11-061
Notice of Change in Policy on the Submission of Plans for Instruction in the Responsible Conduct of Research for Individual and Institutional Career Development Award (K) applications 3/29/11 NOT-OD-11-059
Change in Timetable for Opportunity to Shorten the Review Cycle for New Investigator R01 Applications Reviewed in Study Sections Convened by the Center for Scientific Review (CSR) and National Institute of Mental Health (NIMH)  3/23/11 NOT-OD-11-057
Clarification, Institutional Clinical and Translational Science Award (U54), RFA-RM-11-012 3/23/11 NOT-RM-11-012
Extended Comment Period on Proposed Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition 3/18/11 NOT-OD-11-056
Guidance on the NIH Plan to Transition from the Use of USDA Class B Dogs to Other Legal Sources 3/18/11 NOT-OD-11-055
Delays in Grant Application Submission due to Recent Seismic Events on the Pacific Rim 3/18/11 NOT-OD-11-054
Guidance to Reduce Regulatory Burden for IACUC Administration Regarding Alternate Members and Approval Dates 318/11 NOT-OD-11-053
Registration Now Open for the 13th Annual NIH SBIR/STTR Conference, June 22 & 23, 2011 on the NIH Campus 3/17/11 NOT-OD-11-052
Modification of the Fellowship Biographical Sketch in NIH Grant Application Form SF424 (R&R) to Permit a Description of Factors that may have Resulted in a Hiatus in Training or Reduced Productivity 3/14/11 NOT-OD-11-050
Notice to Encourage Use of Research Project Grant (Parent R01) PA-10-067 and NIH Exploratory Developmental Research Grant Program (Parent R21) PA-10-069 to Support Technology and Methods Development for Genomics, Population Genomics and ELSI Research 3/09/11 NOT-HG-11-016
Notice of Change in Policy on the Submission of Reference Forms (Letters of Reference) for Kirschstein-NRSA Fellowship (F) Applications 2/24/11    NOT-OD-11-047
Reminder of Requirement for Certification Letter for Applications in Response to Kirschstein-NRSA for Individual Predoctoral Fellowships to Promote Diversity in Health-Related Research (PA-11-112) and Deadline for Their Receipt 2/24/11 NOT-OD-11-046
Announcing the Transition of Single Research Project Cooperative Agreements (Single Project U01s) to Electronic Submission for Due Dates on or After May 25, 2011  2/23/11 NOT-OD-11-048
Modification of the Biographical Sketch in NIH Grant Application Forms (PHS 398, PHS 2590, and the SF 424 R&R) to Permit a Description of Factors that may have Reduced Productivity 2/16/11 NOT-OD-11-045
Request for Information (RFI): Input on Strategies for Leveraging Existing Health Data Linked to New or Existing Bio-specimen Repositories for Large Scale Epidemiology Research 2/16/11 NOT-RM-11-008
Request for Information (RFI): Challenges and Opportunities in Single Cell Analysis for Biomedical Research 2/08/11 NOT-RM-11-007

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National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

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