News from NIDCR (National Institute of Dental and Craniofacial Research, NIH)

E-Newsletter: December 5, 2011

In this Issue:
1. NIDCR News
2. NIH News
3. Science Advances
4. Funding Opportunity News


NIDCR News

Upcoming Lecture: Ambassador Eric Goosby to Present 2011 David E. Barmes Global Health Lecture

Eric Goosby, U.S. Global AIDS Coordinator The Department of State's U.S. Global AIDS Coordinator Dr. Eric Goosby will present the 2011 David E. Barmes Global Health Lecture on Tuesday, December 13 at 11:00 a.m. in Masur Auditorium (Bldg. 10) on the NIH campus.

His lecture, titled, "PEPFAR: Moving from Science to Program to Save Lives," will highlight the work done through the President's Emergency Plan for AIDS Relief (PEPFAR), a program launched eight years ago that Goosby currently oversees as ambassador.  

 Ambassador Goosby also manages the federal government's participation in the Global Fund to Fight AIDS, Tuberculosis and Malaria, and serves on the operations committee that leads the Global Health Initiative. 

Jointly sponsored by NIDCR and the Fogarty International Center, the annual lecture series honors the late David E. Barmes, a longstanding World Health Organization employee, special expert for international health at NIDCR, and ardent spokesman for global health.

The lecture is free and open to the public.  It may also be viewed via videocast at:
http://videocast.nih.gov/

Applications Now Accepted for NIDCR's Residency Program in Dental Public Health
Smiling young African American woman NIDCR is accepting applications through December 31, 2011 for its Residency Program in Dental Public Health.  The 12-month full-time or 12-month equivalent part-time program provides a formal training opportunity for dentists planning careers in dental public health with an emphasis on oral and craniofacial, health-related epidemiologic research.  The Residency Program is accredited by the Commission on Dental Accreditation of the American Dental Association.  Program graduates receive a certificate of completion and are qualified educationally to apply for examination by the American Board of Dental Public Health for specialty certification. 

While emphasizing research training and oral disease prevention and health promotion, the residency also provides experience in other areas of dental public health, i.e. public health administration and management, the organization and financing of dental care programs, and the development of resources.  Residents develop an individualized training plan, which describes activities to be undertaken during the residency and conduct at least one research project under the guidance of NIDCR staff and other qualified mentors.  The application and additional information are found at: 
http://go.usa.gov/8J4   

NIDCR Summer Dental Student Award Program Now Accepting Applications

Two male 2011 SDSA awardeesTo expose future dentists to careers in research, NIDCR offers an outstanding summer training opportunity in its intramural research labs for dental students.  The NIDCR Summer Dental Student Award is designed to give talented dental students hands-on research experience and exposure to the latest advances in oral health research.  Selected candidates are assigned to mentors who conduct research in the students' areas of interest.  Participation in the program may result in presentation of research findings at a scientific meeting or co-authorship of scientific publications.

The NIDCR provides a competitive stipend for all summer researchers.  Acceptance of this award requires a minimum eight-week commitment.  The nominating dental school must  agree to support air or ground transportation for their students.  Although housing is not supplied by NIDCR, student housing resource guides are provided. 

NIDCR will accept online applications for the Summer Dental Student Award until January 17, 2012.  For additional information on how to apply, please visit:
http://go.usa.gov/5Cx 
or contact Dr. Deborah Philp, Program Director, dphilp@dir.nidcr.nih.gov (301) 594-8444.

 


NIH News

NIH Operates Under a Continuing Resolution

Image of U.S. Capitol with dollars in background The NIH is operating under a Continuing Resolution (CR) that was signed by President Obama on November 19.  The CR continues government operations through December 16, 2011 at the FY 2011 level minus 1.5 percent.

Until FY 2012 appropriations are enacted, the NIH will issue non-competing research grant awards at a level below that indicated on the most recent Notice of Award (generally up to 90% of the previously committed level).  This is consistent with NIH's practice during the CRs of FY 2006 - 2011.  Upward adjustments to awarded levels will be considered after NIH's FY 2012 appropriations are enacted, but NIH expects institutions to monitor their expenditures carefully during this period.  

NIH Answers Call to Streamline Technology Transfer Process
NIH is launching the electronic Research Materials catalogue (eRMa) to streamline the process by which companies access technologies developed by researchers in NIH's intramural programs.  The project addresses one of the most important directives in a Presidential memorandum related to the commercialization of federal research and support for high-growth business potential. 

Researchers in NIH laboratories make unpatented materials available to companies through internal use licenses executed by the NIH Office of Technology Transfer.  An internal use license is a contract that governs the transfer of tangible research materials from NIH to a company for commercial research use. 
The new system will streamline the licensing process by providing a website for companies to find and license unpatented materials using a ready-to-go-contract; allowing a company to pay online through Pay.gov and receive the materials from the lab quickly; and providing faster turn-around time and simplifying the process for companies to find research materials available from NIH labs.  See the NIH electronic Materials Research catalogue:
http://www.ott.nih.gov/erma/ 

NIH Program Allows Junior Investigators to Bypass Traditional Post-Doc Training

Early Independence Award Program logoA program designed to accelerate the entry of outstanding junior investigators into independent researcher positions immediately following completion of their graduate research degree or clinical residency has announced its first recipients.  The NIH's Early Independence Award (EIA) is part of an NIH-wide effort to empower the biomedical research workforce, particularly through the support of investigators early in their careers.  The EIA program effectively allows awardees to leapfrog over the traditional post-doctoral training period, capitalizing on the creativity, confidence, and energy of young scientists.  The first group of awardees includes 10 exceptional junior investigators.  NIH plans to commit approximately $19.3 million to support their research projects over a five-year period. 
Read more about the awardees:
http://www.nih.gov/news/health/sep2011/od-30.htm

Applications are now being accepted through January 30, 2012 for the next round of Early Independence Awards.  See detailed instructions on how to apply:
http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-11-007.html

More information about the program is also found at:
http://commonfund.nih.gov/earlyindependence/

Lasker Clinical Research Scholars Program (Si2)
NIH Clinical CenterApplications are invited for the Lasker Clinical Research Scholars Program that supports research activities during the early stage careers of independent clinical researchers. 

The program offers the opportunity for a unique bridge between the NIH intramural and extramural research communities, and contains two phases.  In the first phase, Lasker scholars will receive appointments for up to 5-7 years as tenure-track investigators within the NIH Intramural Research Program with independent research budgets.  In the second phase, successful scholars will be eligible to apply for up to 5 years of NIH support for their research at an extramural research facility, or the scholar can be considered to remain as an investigator within the intramural program.

Applications will be accepted until January 24, 2012.  See additional details:
http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-12-001.html     

NIH to Make a Mightier Mouse Resource for Understanding Disease

knockout mouseOver the next five years, NIH-funded researchers will extensively test and generate data about mice with disrupted genes to gain clues about human diseases.  NIH has awarded a set of cooperative agreements totaling more than $110 million to begin the second phase of the Knockout Mouse Project (KOMP).  The results of the next stage, called the Knockout Mouse Phenotyping Project, or KOMP2, will be placed in a public database.  Researchers make knockout mice by disrupting the function of individual genes across the animal's genome.  KOMP2 is a trans-NIH and NIH Common Fund project that will work with other members of the International Knockout Mouse Phenotyping Consortium (IMPC) to generate about 5,000 strains of knockout mice that will undergo a large battery of clinical phenotype tests.  In the long term, the project aims to enable the research community to establish the traits associated with the function of every protein-coding gene in the mammalian genome.  Such information will be valuable for the discovery of the genetic causes of human diseases and will aid efforts to identify new drug targets.   NIDCR is one of the 18 NIH institutes, centers and offices contributing to the Knockout Mouse Project.  More information about KOMP is found at: 
http://www.nih.gov/science/models/mouse/knockout/ 

NIH to Fund Development of K-12 Neuroscience Education Programs

Eight investigators across the United States will receive funding over the next five years to develop innovative neuroscience education programs for K-12 students and their teachers.  The grants are funded by the NIH Blueprint for Neuroscience Research Science Education Award and the Science Education Partnership Award Program.  NIDCR is one of the NIH institutes supporting both of these awards. 

The educational programs aim to increase science literacy and understanding as well as an interest in science among K-12 students and their teachers.  Read more about the awardees:
http://www.nih.gov/news/health/sep2011/nida-27.htm

NIH Grantees Win 2011 Nobel Prize in Physiology or Medicine

The 2011 Nobel Prize in Physiology or Medicine has been awarded to NIH grantees Bruce A. Beutler, M.D., of The Scripps Research Institute, La Jolla, CA, and Jules A. Hoffmann, Ph.D., for their discoveries concerning the activation of innate immunity and the late Ralph M. Steinman, M.D., of Rockefeller University, NY, for his discovery of the dendritic cell and its role in adaptive immunity.  "The work of these three NIH-supported scientists has provided fundamental understanding of the body's immune system, and has been pivotal to the development of new vaccines against infectious diseases and treatments for cancer," said NIH director Francis S. Collins, M.D., Ph.D.  

Dr. Chris Kaiser to Lead National Institute of General Medical Sciences

Chris Kaiser, Ph.D.Dr. Collins has announced the appointment of Chris A. Kaiser, Ph.D., as the new director of the National Institute of General Medical Sciences.  Dr. Kaiser, a leader in cell biology, is professor and head of the Department of Biology at the Massachusetts Institute of Technology.  He expects to start his new position in the spring of 2012.

Dr. Kaiser will replace Judith H. Greenberg, Ph.D., who became acting director of NIGMS in July 2011 after the departure of Jeremy Berg, Ph.D., who had served as director since 2003. 


SCIENCE ADVANCES
 

P. gingivalisTo Its Microbial Liking
Scientists have solved in mice how P. gingivalis orchestrates conditions that lead to periodontitis.  Read more about it:
http://go.usa.gov/522









Roberto Weigert, Ph.D. Looking Anew
Scientists observed a key subcellular process through an IVM microscope and caught a telling new glimpse of how the biology works.   Find out more:
http://go.usa.gov/52T








Profile of face showing location of temporomandibular jointOPPERA Update
Study issues early results on risk factors for chronic TMJD.  See
additional information:
http://go.usa.gov/52D


FUNDING OPPORTUNITY NEWS

PROGRAM ANNOUNCEMENTS

Neurobiology/Pain

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Etiology, Diagnosis, Pathophysiology, and Treatment (R01) 11/18/11 PAR-12-032 John Kusiak
301-594-7984
10/25/14
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Etiology, Diagnosis, Pathophysiology, and Treatment (R21) 11/18/11 PAR-12-033 John Kusiak
301-594-7984
10/25/14

Research Mechanisms

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
Academic Research Enhancement Award (Parent R15) 11/02/11 PA-12-006 Alicia Dombroski
301-594-4805
1/08/15
Career Development

Title NIH
Guide
PA
Number
NIDCR Contact Expiration
Date
NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22) 10/21/11 PAR-12-004 James Melvin
301-402-1706

Kevin Hardwick
301-594-2765
1/08/15

REQUESTS FOR APPLICATIONS

Clinical Research/Clinical Trials

Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Lasker Clinical Research Scholars Program (Si2) 11/18/11 RFA-OD-12-001

Kevin Hardwick
301-594-2765


Jim Melvin
301-402-1706
1/24/12

NIH Roadmap Initiatives

Title NIH
Guide
RFA
Number
NIDCR Contact Application Receipt Date
Studies to evaluate cellular heterogeneity using transcriptional profiling of single cells (U01) 11/23/11 RFA-RM-11-013

Lillian Shum
301-594-0618

1/23/12
Exceptionally Innovative Tools and Technologies for Single Cell Analysis (R21) 11/23/11 RFA-RM-11-014

Lillian Shum
301-594-0618

1/23/12
Accelerating the Integration and Translation of Technologies to Characterize Biological Processes at the Single Cell Level (R01) 11/23/11 RFA-RM-11-015

Lillian Shum
301-594-0618

1/23/12
Stem/Progenitor Cell-Derived Human Micro-organs and -tissues (U18) 11/23/11 RFA-RM-12-001

Nadya Lumelsky
301-594-7703

1/26/12
Technology Development to Enable Large Scale Metabolomics Analyses (R01) 11/17/11 RFA-RM-11-019

Lillian Shum
301-594-0618

1/31/12
NIH Director's Early Independence Awards (DP5) 11/10/11 RFA-RM-11-007 Mary Greenwood
301-594-4808
1/30/12
Economic Studies Ancillary to Completed or Ongoing Health Care Delivery and Financing Pilots, Demonstrations, and Other Experiments (R01)  10/07/11 RFA-RM-11-023 David Clark
301-594-4814
2/08/12
Phased Economic Studies Ancillary to Planned Health Care Delivery and Financing Pilots, Demonstrations, and Other Experiments (R21/R33) 10/07/11 RFA-RM-011-024 David Clark
301-594-4814
2/08/12

 NOTICES

Title NIH
Guide
Notice Number
Adoption and Implementation of the Guide for the Care and Use of Laboratory Animals: Eighth Edition 12/02/11 NOT-OD-12-020
Frequently Asked Questions for RFA-MH-12-130 - OppNet's Basic Research on Decision Making: Cognitive, Affective, and Developmental Perspectives (R01) 12/01/11 NOT-OD-12-019
The NIH Operates Under a Continuing Resolution 11/21/11 NOT-OD-12-017
Notice of Expanded Transparency Act Subaward and Executive Compensation Reporting Requirements for FY 2012 and Beyond 11/10/11 NOT-OD-12-010
Notice of Availability of Administrative Supplements for Adolescent Substance Use Screening Tool Development and Validation for U.S. General Medical and Dental Settings 10/28/11 NOT-DA-12-002
Publication of the Revised NIH Grants Policy Statement (Rev. 10/1/2011): Policy Changes, Clarifications and Document Enhancements 10/20/11 NOT-OD-12-003
Update of NIH Late Application Policy to Reflect Change in Due Dates for New Investigator R01 Resubmission Applications 10/05/11 NOT-OD-12-001
NIH Announces the Posting of Frequently Asked Questions (FAQs) applicable to the 2011 revised regulation on the Responsibility of Applicants for Promoting Objectivity in Research for which PHS Funding is Sought for All NIH-Supported Institutions 9/30/11 NOT-OD-11-121

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National Institute of Dental and Craniofacial Research
National Institutes of Health
Bethesda, MD 20892-2190
301-496-4261

Department of Health and Human Services (HHS)   National Institutes of Health (NIH)   USA.gov