Meet the 2005 Kreshover Lecturer: Dr. Charles Serhan
Dr. Charles N. Serhan, the Simon Gelman Professor at Harvard Medical School and director of the Center for Experimental Therapeutics and Reperfusion Injury at the Brigham and Women's Hospital, will deliver the 2005 NIDCR Seymour J. Kreshover Lecture. Dr. Serhan, an NIDCR grantee, will present a talk titled, "The Role of Novel Anti-Inflammatory and Pro-Resolving Lipid Mediators in Oral Inflammation and Resolution." In advance of the lecture, The Inside Scoop talked to Dr. Serhan about his career in science and ongoing research interests. more... Looking at the Periodontal-Systemic Connection
Studies within the past ten years have suggested an association between periodontal disease and the likelihood of delivering preterm, low-birthweight babies, developing cardiovascular disease, and having difficulty controlling blood sugar levels in people with diabetes. Some studies have also linked periodontal disease to respiratory infection in people with pulmonary problems. The Inside Scoop recently spoke with Bruce Pihlstrom, D.D.S., M.S., acting director of NIDCR's Division of Clinical Research and Health Promotion, about the Institute's clinical research on periodontal disease and its relationship to systemic disease. more...
Building a Dental Practice-Based Research Network
The NIDCR last Spring awarded three seven-year grants, totaling $75 million, to establish "practice-based" research networks (PBRNs) that investigate with greater scientific rigor "everyday" issues in the delivery of oral healthcare. The impetus behind the networks is the frequent lack of research data to guide treatment decisions in the dentist's office. The Inside Scoop recently spoke with the principal investigators of these three grants to hear their thoughts on PBRNs, their organization, and how they will improve oral health. more...Dental Enamel: From Matrix to Microribbons
Many dental researchers dream of one day stepping into the laboratory, putting out a detailed set of instructions, and engineering a replacement tooth. This decades-old dream has gained momentum recently as scientists have identified more of the molecules that nature employs to make a tooth. Yet, even as these molecular parts are identified, scientists must begin to solve the larger puzzles of how they self assemble to form the tooth's various specialized tissues, such as enamel and tooth. more...
Chronic Periodontitis: Geographic Differences in the Oral Biofilm
It has long been assumed that all chronic periodontitis is the same no matter where one lives in the world. But some scientists have wondered whether the bacterial composition of the oral biofilm - the sticky, mat-like microbial communities that form on our teeth and cause chronic periodontitis - might vary geographically. In the November issue of the Journal of Clinical Periodontology, NIDCR grantees and their colleagues report for the first time that this is indeed the case. more...