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Improving Dental Care through Research
(December 2014)
Dr. Gregg Gilbert In 2012, NIDCR awarded a $66.8 million, seven-year grant that consolidated its three regional dental practice-based research networks into one nationally coordinated effort. The consolidated initiative, renamed the National Dental Practice-Based Research Network is headquartered at the University of Alabama at Birmingham (UAB) School of Dentistry. UAB leads and oversees the six regional research sites of the network. Science Spotlight recently spoke with Gregg Gilbert D.D.S., M.B.A., the National Network Director and Chair of the UAB School of Dentistry’s Department of Clinical & Community Sciences, for an update on the network.  Read more...

The Oral Microbiome: From Bad Bugs to Bad Biofilm Behaviors
(November 2014)
Dr. Frias LopezCompelling metagenomic and metatranscriptomic data have begun to enter the periodontitis research literature.  Among the most fascinating is a paper published in the August 2014 issue of the ISME Journal by a team of researchers at the Forsyth Institute in Cambridge, MA.  The team compared the metagenomes and metatranscriptomes of several people with chronic periodontitis to those of healthy volunteers.  The results, though preliminary, provide a fascinating glimpse into progression. In a follow-up article, published in the August issue of the journal Infection and Immunity, the scientists found a needle in their many haystacks of data to generate a new lead in understanding how P. gingivalis can disrupt a healthy biofilm. The Science Spotlight recently spoke with Jorge Frias-Lopez, Ph.D., a microbial ecologist at Forsyth and a senior author on both papers. Read more....

(February 2014)
William Maixner, DDS, PhDDr. Gary SladeIn December 2013, the Journal of Pain published a special issue that featured the latest findings from the NIDCR-supported clinic​al study Orofacial Pain: Prospective Evaluation and Risk Assessment (OPPERA). The latest OPPERA findings, folded into eight original articles and a summary paper, presents the most in-depth picture to date of the factors that may contribute to a person developing a first bout of a painful temporomandibular disorder, or TMD. Science Spotlight spoke recently to Gary Slade, B.D.Sc, D.D.P.H., Ph.D., and William Maixner, D.D.S., Ph.D., two of the study leaders. Read more...... ​​​​

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This page last updated: December 17, 2014