Staff Scientist: Mass Spectrometry Facility

Position Description: The National Institute of Dental and Craniofacial Research (NIDCR) is recruiting a highly motivated scientist to run a newly established Mass Spectrometry Facility and contribute to a diverse range of projects utilizing mass spectroscopy to solve important biological problems. The individual will be responsible for the day-to-day operation of a Mass Spectrometry Facility while providing consultation regarding experimental design and sample preparation. Experience is preferred with experimental approaches that include, but are not limited to, differential proteomics and differential glycoproteomics (e.g. by using TMT-labeling strategies); identification and mapping of sites of O-glycosylation and ubiquitylation. The successful candidate will be skilled in and responsible for all aspects of method development, sample preparation, chromatography, data acquisition, data analysis and data interpretation using a variety of separations, mass spectrometry, and software platforms. Responsibilities also include mass spectrometer maintenance, providing project support, effectively communicating project progress, writing technical summaries, participating in all aspects of publication and grant writing, and maintaining, updating and troubleshooting of LC/MS instrumentation.


  • PhD in biochemistry, clinical, (bio)analytical chemistry or related disciplines;
  • Documented hands-on experience with quantitative LC/MS; particularly important is expertise with ion fragmentation techniques including ETD, HCD, and CID;
  • Experience with site-specific mapping of O-glycans and/or ubiquitin is a major plus;
  • Ability to work accurately, with attention to detail, in a highly organized manner;
  • Team player who can collaborate with multiple functional groups.

Salary and Benefits: The current salary range is commensurate with experience and accomplishments; a full package of benefits (including retirement, health, life and long-term care insurance, Thrift Savings Plan participation, etc.) is available.

To Apply: Please submit a cover letter describing your interest in the position including a career synopsis (1 pages), statement of research interests (1 pages), a current curriculum vitae and complete bibliography, and the names and contact information of three references to Ms. Shirley Simpson (

Application packages will be accepted electronically until the position has been filled.

All information provided by candidates will remain confidential and will not be released outside the NIDCR search process without a signed release from candidates. The NIH encourages the application and nomination of qualified women, minorities and individuals with disabilities. DHHS and NIH are Equal Opportunity Employers.

Last Reviewed
July 2018