Notices of Funding Opportunities

The table below lists all active NIDCR Notices of Funding Opportunitites (NOFOs). Use the filters to sort by funding type, topic, or activity code. Use the search box to find funding opportunities that include specific keywords. Click on title to see more details.

 

295 Results
Title Release Date Expiration Date
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects

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Topics: Epidemiology, Mucosal Diseases, Oral, Oropharyngeal & Salivary Gland Cancers

View more details on grants.nih.gov

Continuation or Revision of NIDCR Clinical Trial Implementation Cooperative Agreement (UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials

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Notice of Intent to Publish a Funding Opportunity Announcement for NIH Neuroscience Doctoral Readiness Program (DR. Program) (R25 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to support research that will advance the measurement and assessment of complex constructs relevant to minority health and health disparities.

Contact:

Topics: Oral Health Disparities & Inequities

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Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs). Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

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Topics: Clinical Research & Clinical Trials

View more details on grants.nih.gov

Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)

The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs). Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.

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Topics: Clinical Research & Clinical Trials, Parent Announcements & Trans-NIH Announcements

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Notice of Special Interest (NOSI): The Functional Oral Microbiome

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Topics: Oral Microbiology & Metagenomics

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Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA

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Topics: Parent Announcements & Trans-NIH Announcements

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Notice of Intent to Publish the "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15, Clinical Trial Required)" FOA
Notice of Special Interest: SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed)

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Topics: Small Business (SBIR/STTR)

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Reminder: FORMS-G Grant Application Forms & Instructions Must be Used for Due Dates On or After January 25, 2022 - New Grant Application Instructions Now Available

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Topics: Career Development, Research Training & Fellowships

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Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03)

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Topics: Behavioral & Social Science, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Epidemiology, HIV/AIDS & Oral Health, Mucosal Diseases, Oral Health Disparities & Inequities, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Periodontal Diseases, Salivary Biology & Dysfunction

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Request for Information (RFI): Joint Pain and Innervation Research

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in PAR-21-287 Effectiveness of School-Based Health Centers to Advance Health Equity (R01 Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Notice of Special Interest (NOSI): Biologic Factors Underlying Dental, Oral, and Craniofacial Health Disparities

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Topics: Oral Health Disparities & Inequities

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Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required)

This funding opportunity announcement (FOA) invites research projects that seek to explain the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in human health, illness, recovery, and overall wellbeing. Types of projects submitted under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical and/or behavioral outcomes in humans to understand fundamental aspects of phenomena related to social connectedness and isolatedness. NIH considers such studies as prospective basic science studies involving human participants that meet the NIH definition of basic research and fall within the NIH definition of clinical trials (see, e.g., NOT-OD-19-024) Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Applications proposing studies that include but not limited to model animal research or observational studies involving humans should submit under the companion Clinical Trials Not Allowed version of this FOA.

Contact:

Topics: Behavioral & Social Science

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Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Clinical Trials Not Allowed)

This funding opportunity announcement (FOA) invites research projects that seek to model the underlying mechanisms, processes, and trajectories of social relationships and how these factors affect outcomes in health, illness, recovery, and overall wellbeing. Both animal and human subjects research projects are welcome. Researchers proposing basic science experimental studies involving human participants should consider the companion FOA TEMP-14931 "Research on Biopsychosocial Factors of Social Connectedness and Isolation on Health, Wellbeing, Illness, and Recovery (R01 Basic Experimental Studies with Humans Required)".

Contact:

Topics: Behavioral & Social Science

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INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

Contact:

Topics: Behavioral & Social Science, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Epidemiology

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NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials

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Updates to the Non-Discrimination Legal Requirements for NIH Recipients

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Topics: Career Development, Research Training & Fellowships

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Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)

The National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) hereby notify Small Business Concerns (SBCs) holding Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants that funds are available for administrative supplements to improve the diversity of the research workforce by recruiting and supporting students, postdoctorates, and eligible investigators from groups that have been shown to be nationally underrepresented in health-related research or in the SBIR and STTR programs. This supplement opportunity is also available to PD(s)/PI(s) of research grants who are or become disabled and need additional support to accommodate their disability in order to continue to work on the research project. Administrative supplements must support work within the scope of the original project. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.

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Topics: Small Business (SBIR/STTR)

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Notice of Intent to Publish a Funding Opportunity Announcement for NIH Blueprint for Neuroscience Research Short Courses in Neurotherapeutics Development (R25 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Dissemination & Implementation Science

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Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed)

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Topics: Small Business (SBIR/STTR), Technology Development

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Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage investigators to pursue translational activities and clinical feasibility studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent clinical feasibility study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This FOA is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress. Participants in Blueprint MedTech receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants to receive assistance with specialty areas including regulatory, reimbursement, intellectual property, commercialization, and strategic partnerships. Participants can also augment their project with NIH contract research organizations that specialize in large animal testing, sterilization testing, biocompatibility assessment, manufacturing, and medical monitoring. Individuals, institutions, or businesses developing their own devices or that already have established collaborations with device manufacturers are welcome to apply directly to this FOA or any of the companion opportunities. For more information see BP MedTech website.

Contact:

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Special Interest (NOSI): Social, Behavioral, and Economic Impact of COVID-19 in Underserved and Vulnerable Populations

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Topics: Behavioral & Social Science, Dissemination & Implementation Science, Women's Health

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Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH))

The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.

Contact:

Topics: Career Development, Research Training & Fellowships

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Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required)

The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.

Contact:

Topics: Career Development, Research Training & Fellowships

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Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)

The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.

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Topics: Career Development, Research Training & Fellowships

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Notice of Special Interest (NOSI): Precision Imaging of Oral Lesions

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of Expiration of PAR-21-197, NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required).

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Topics: Behavioral & Social Science

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Effectiveness of School-Based Health Centers to Advance Health Equity (R01 Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Technology Development

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Notice of Corrected Application Forms and Extended Receipt date for RFA-DE-22-002 Addressing Social Determinants of Health to Eliminate Oral Health Disparities (UG3/UH3 Clinical Trials Optional)

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Topics: Oral Health Disparities & Inequities

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Notice of Correction to Application Types Allowed for PAR-21-197, NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Oral Health Disparities & Inequities

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Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

The National Institutes of Health (NIH) hereby notify recipient organizations holding specific types of NIH grants, listed in the full Funding Opportunity Announcement (FOA), that applications for change of recipient organization may be submitted to this FOA. This assumes such a change is programmatically permitted for the particular grant. Applications for change of recipient organization are considered prior approval requests (as described in Section 8.1.2.7 of the NIH Grants Policy Statement) and will be routed for consideration directly to the Grants Management Specialist named in the current award. Although requests for change of recipient organization may be submitted through this FOA, there is no guarantee that an award will be transferred to the new organization. All applicants are encouraged to discuss potential requests with the awarding IC before submission.

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Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Career Development, Clinical Research & Clinical Trials, Common Fund Programs, Conferences & Meetings, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, National Dental Practice-Based Research Network, Oral & Comprehensive Health, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Periodontal Diseases, Salivary Biology & Dysfunction, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Research Training & Fellowships

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Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects

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Topics: Epidemiology, Mucosal Diseases, Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of NIDCR Participation in RFA-CA-21-035 The Early Detection Research Network: Biomarker Characterization Centers (U2C Clinical Trial Not Allowed)

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of NIDCR Participation in PAR-21-168, "Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)"

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Topics: Career Development, Research Training & Fellowships

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Notice of a Pre-Application Technical Assistance Webinar for NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00)

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Topics: Career Development, Research Training & Fellowships

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Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students, and enhancing the research environment at these applicant institutions. Eligible institutions must award baccalaureate science degrees, and have received less than 6 million dollars per year of NIH support (total costs) in 4 of the last 7 fiscal years.

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Topics: Parent Announcements & Trans-NIH Announcements

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Notice of Early Termination of RFA-NS-21-016, HEAL Initiative: Planning Studies for Initial Analgesic Development Initial Translational Efforts [Small Molecules and Biologics] (R34 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint MedTech: Translator (UG3/UH3 Clinical Trial Optional)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint Medtech: Small Business Translator (U44)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint MedTech: Incubator Hubs (U54 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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RESCINDED - Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint MedTech: Prototype Developer (U18 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this R25 program is to support educational activities that foster a better understanding of biomedical, behavioral and clinical research and its implications. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on research experiences for high school or undergraduate students or science teachers during the summer academic break. The proposed program needs to fit within the mission of the participating IC that the application is being submitted to and should not have a general STEM focus (see below and Table of IC-Specific Information and Points of Contact).

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Topics: Career Development, Research Training & Fellowships

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Screening and Functional Validation of Human Birth Defects Genomic Variants (R01 Clinical Trial Not Allowed)

Rapid advances in genotyping and next generation sequencing technologies have led to the identification of genetic variants that are associated with a wide variety of congenital defects including structural birth defects (SBDs), intellectual developmental disabilities (IDDs) and inborn errors of metabolism (IEMs). Large quantities of genomic data collected from pediatric birth defects cohorts are available to the research community through several databases such as the Database of Genotypes and Phenotypes (dbGaP), the Gabriella Miller Kids First Data Resource Portal, the European Genome-Phenome Archive and Clinical Genome Resource (ClinGen). The purpose of this initiative is to promote the screening, functional validation and characterization of birth defects-associated genetic variants identified through public facing databases and individual efforts using in-silico tools, appropriate animal models, in vitro systems or multi-pronged approaches. This initiative addresses a challenging gap between identifying sequence variations of potential interest and recognizing which of those variations have functional effects on the phenotype of interest.

Contact:

Topics: Craniofacial & Dental Developmental Biology

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Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

Contact:

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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RESCINDED - NIDCR Policy on Applications for Investigator-Initiated Clinical Trials

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials

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Notice of Intent to Reissue PAR-18-845 Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed) and PAR-18-846 (R21 - Clinical Trial Not Allowed) as a Notice of Special Interest (NOSI)

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Continuation of Temporary Extension of Eligibility for the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) During the COVID-19 Pandemic

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Topics: Career Development, Research Training & Fellowships

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Notice of Intent to Reissue PAR-18-847 Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Prevention Research (R01- Clinical Trial Optional) and PAR-18-848 (R21 - Clinical Trial Optional) as a Notice of Special Interest (NOSI)

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of Change to PAR-20-238, "Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)"

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Topics: Oral Health Disparities & Inequities

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NIH Blueprint for Neuroscience Research: Request for Information (RFI) on Neuroimmune Interactions in the Healthy CNS

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Oral Health Disparities & Inequities

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Notice of Correction to R&R Budget Form for PAR-21-160, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

Contact:

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

View more details on grants.nih.gov

Notice of Special Interest (NOSI): Availability of Administrative Supplements for Childcare Costs for Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellows

Topics: Research Training & Fellowships, Parent Announcements & Trans-NIH Announcements

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Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for Accelerating Medicines Partnership Autoimmune and Immune-Mediated Diseases: Technology and Analytic Cores (TACs) and Research Management Unit (RMU) (UC2) (Clinical Trials Not Allowed)

Topics: Oral Immunology, Immunopathology & Immunotherapy

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Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for Understanding and Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)

Topics: Oral Health Disparities & Inequities

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HEAL Initiative: EPPIC-Net Pain Research Asset Application (OT2)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Planning Studies for Initial Analgesic Development Initial Translational Efforts [Small Molecules and Biologics]

Topics: Parent Announcements & Trans-NIH Announcements, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Special Interest (NOSI): Promoting Research on Interoception and Its Impact on Health and Disease

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Expiration of PAR-19-370 NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed)
Notice of NIH Participation in Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science

Topics: Bioinformatics, Computational Biology & Data Science

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Notice to Extend the Expiration Date for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Topics: Clinical Research & Clinical Trials

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Notice to Extend the Expiration Date for PAR-18-656, NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Notice of Special Interest to Encourage Eligible NIH HEAL Initiative Awardees to Apply for PA-20-222: Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Notice of NIDCR's Participation in PA-20-135 "Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional)"

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Topics: COVID-19, Parent Announcements & Trans-NIH Announcements

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Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)"

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Topics: Behavioral & Social Science, COVID-19, Periodontal Diseases, Salivary Biology & Dysfunction, International Research Activities, Global Health, Fluoride & Fluorosis, Dental Materials & Biomaterials, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Research Training & Fellowships, Common Fund Programs, Career Development, Mucosal Diseases, Tissue Engineering & Regenerative Medicine, Parent Announcements & Trans-NIH Announcements, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Oral, Oropharyngeal & Salivary Gland Cancers, Oral Microbiology & Metagenomics, Oral Immunology, Immunopathology & Immunotherapy, Oral Health Disparities & Inequities, National Dental Practice-Based Research Network, Mineralized Tissues & Mineralization, Bioinformatics, Computational Biology & Data Science, Dental Caries, Clinical Research & Clinical Trials, Conferences & Meetings, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dissemination & Implementation Science, Epidemiology, Gene Discovery, Genomics & Multi-Omics Analysis, HIV/AIDS & Oral Health

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Notice of Additional Receipt Dates for PAR-20-073 National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed)
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools"

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Topics: Bioinformatics, Computational Biology & Data Science, Parent Announcements & Trans-NIH Announcements

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Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional)

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Topics: Behavioral & Social Science, Periodontal Diseases, Salivary Biology & Dysfunction, Global Health, Fluoride & Fluorosis, Dental Materials & Biomaterials, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Common Fund Programs, Mucosal Diseases, Tissue Engineering & Regenerative Medicine, Parent Announcements & Trans-NIH Announcements, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Oral, Oropharyngeal & Salivary Gland Cancers, Oral Microbiology & Metagenomics, Oral Immunology, Immunopathology & Immunotherapy, Oral Health Disparities & Inequities, National Dental Practice-Based Research Network, Mineralized Tissues & Mineralization, Bioinformatics, Computational Biology & Data Science, Dental Caries, Clinical Research & Clinical Trials, Conferences & Meetings, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dissemination & Implementation Science, Epidemiology, Gene Discovery, Genomics & Multi-Omics Analysis, HIV/AIDS & Oral Health

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Notice of NIDCR Participation in PAR-19-343 "Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Not Allowed)"

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Topics: Research Training & Fellowships

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Notice of Change to salary allowance for K00 awardees for NIH Blueprint Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Independent Clinical Trial Not Allowed)

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Topics: Research Training & Fellowships, Career Development

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Notice to Update Eligibility for the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Independent Basic Experimental Studies with Humans Required) PAR-19-141

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Topics: Research Training & Fellowships, Career Development

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Notice of Clarification Relevant to Section IV, Application and Submission Information for PAR-20-045 NIDCR Research Grants for Analyses of Existing Genomics Data (R01 Clinical Trial Not Allowed)

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Topics: Bioinformatics, Computational Biology & Data Science

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Notice of Clarification Relevant to Section IV, Application and Submission Information for PAR-20-046 NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)

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Topics: Bioinformatics, Computational Biology & Data Science, Statistical Analysis & Data Science

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Notice of NIDCR Participation in PAR-19-380 Initiative to Maximize Research Education in Genomics: Diversity Action Plan (R25)

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Topics: Career Development, Research Training & Fellowships

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Notice of Changes to NIDCR's Clinical Terms of Award (CToA) Policy

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Topics: Behavioral & Social Science, Periodontal Diseases, Salivary Biology & Dysfunction, International Research Activities, Global Health, Fluoride & Fluorosis, Dental Materials & Biomaterials, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Research Training & Fellowships, Common Fund Programs, Career Development, Mucosal Diseases, Tissue Engineering & Regenerative Medicine, Parent Announcements & Trans-NIH Announcements, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Oral, Oropharyngeal & Salivary Gland Cancers, Oral Microbiology & Metagenomics, Oral Immunology, Immunopathology & Immunotherapy, Oral Health Disparities & Inequities, National Dental Practice-Based Research Network, Mineralized Tissues & Mineralization, Bioinformatics, Computational Biology & Data Science, Dental Caries, Clinical Research & Clinical Trials, Conferences & Meetings, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dissemination & Implementation Science, Epidemiology, Gene Discovery, Genomics & Multi-Omics Analysis, HIV/AIDS & Oral Health

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Notice to Extend the Expiration Date for PA-18-141 "Mechanisms, Models, Measurement, & Management in Pain Research (R01 Clinical Trial Optional)"
Notice of NIDCR's Participation in PAR-18-831 "The Role of Epitranscriptomics in Development and Disease (R21 - Clinical Trial Not Allowed)"

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Topics: Gene Discovery, Genomics & Multi-Omics Analysis

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Notice of NIDCR's Participation in PAR-18-830 "The Role of Epitranscriptomics in Development and Disease (R01 - Clinical Trial Not Allowed)"

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Topics: Gene Discovery, Genomics & Multi-Omics Analysis

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Notice of NIDCR's Participation in PAR-19-194 "Microbial-based Cancer Therapy-Bugs as Drugs (R21- Clinical Trial Not Allowed)"

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of NIDCR's Participation in PAR-19-193 "Microbial-based Cancer Therapy-Bugs as Drugs (R01- Clinical Trial Not Allowed)"

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of Clarification of Award Budget for PAR-18-656 NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science

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Notice of Corrected Application Forms for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Clinical Research & Clinical Trials, Dissemination & Implementation Science

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Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed)

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Topics: Parent Announcements & Trans-NIH Announcements

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Notice of Correction to PAR-18-656 "NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials

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