Notices of Funding Opportunities

The table below lists all active NIDCR Notices of Funding Opportunitites (NOFOs). Use the filters to sort by funding type, topic, or activity code. Use the search box to find funding opportunities that include specific keywords. Click on title to see more details.

 

295 Results
Title Release Date Expiration Date
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

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Topics: Parent Announcements & Trans-NIH Announcements

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Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional)

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Topics: Parent Announcements & Trans-NIH Announcements

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Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
Centers for AIDS Research (P30 Clinical Trial Not Allowed)
NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19)

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Topics: Clinical Research & Clinical Trials, COVID-19, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics

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Notice to Extend the Expiration Date for All NIH Career Development Award (K) Parent Announcements

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Topics: Research Training & Fellowships

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Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains Exhibiting Embryonic or Perinatal Lethality or Subviability (R01 Clinical Trial Not Allowed)

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Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology

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Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases

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Topics: Epidemiology, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Small Research Grants for Analyses of Gabriella Miller Kids First Pediatric Research Data (R03 Clinical Trial Not Allowed)

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Topics: Craniofacial & Dental Developmental Biology

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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (K99/R00 Independent Clinical Trial Not Allowed)

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Topics: Research Training & Fellowships

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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (Independent Basic Experimental Studies with Humans Required)

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Topics: Research Training & Fellowships

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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Basic Experimental Studies with Humans Required)

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Topics: Research Training & Fellowships

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Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards

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Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, Common Fund Programs, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral & Comprehensive Health, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Periodontal Diseases, Salivary Biology & Dysfunction, Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health

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Notice of Special Interest: Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars

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Topics: Career Development, Research Training & Fellowships

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The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Oral Health Disparities & Inequities, Women's Health

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Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program KL2/K12 Institutional Career Development Awards as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project

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Topics: Career Development, Research Training & Fellowships

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INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Research Short Course (R25 Independent Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Notice of Special Interest (NOSI): Implementation Science to Advance Maternal Health and Maternal Health Equity for the IMPROVE initiative

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Topics: Behavioral & Social Science, Dissemination & Implementation Science, Women's Health

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HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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Notice of Special Interest (NOSI): Development and Preliminary Testing of Health-related Behavioral Interventions

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Topics: Behavioral & Social Science

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Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed)

The purpose of this funding opportunity announcement is to encourage collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science.

Contact:

Topics: Dental Materials & Biomaterials, Tissue Engineering & Regenerative Medicine

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Notice of Technical Assistance Webinar for RFA-DE-23-012 Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED)

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Topics: Clinical Research & Clinical Trials

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Request for Information (RFI): Investigators interests in and barriers to research studies on the health effects of cannabis and its constituents

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Topics: Epidemiology, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Pre-Application Webinar for RFA-DE-23-006, RFA-DE-23-007, and RFA-DE-23-008, Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials

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Topics: Dental Materials & Biomaterials

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HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to develop clinical-grade prototypes intended for use as safe, effective, and non-addictive device-based technologies and approaches to treat pain. The goal of the program is to demonstrate treatment using credible neural targets for device-based interventions and/or diagnostics for pain, building upon the latest mechanistic knowledge about the anatomy and physiology of central, spinal, and peripheral pathways involved in pain. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.

Contact:

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Technology Development

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Notice of Intent to Publish a Funding Opportunity Announcement for Community Partnerships to Advance Science for Society (ComPASS): Coordination Center (U24 - Clinical Trial Optional)
Notice of Information: Upcoming Research Opportunity Announcement (ROA) for Community Partnerships to Advance Science for Society (ComPASS) Program: Community-Led, Health Equity Structural Intervention Initiative (CHESI) (OT2 Clinical Trial Optional)
Notice of Change in Receipt Date for Applications to Harnessing Technologies to Support Oral Health Promotion and Management Outside the Dental Setting (RFA-DE-23-009)

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Topics: Behavioral & Social Science

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Notice of the Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in RFA-OD-22-015 Galvanizing Health Equity Through Novel and Diverse Educational Resources (GENDER) Research Education R25 (Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Notice of Special Interest (NOSI): Community-Based Participatory Research (CBPR) Initiative in Reducing and Eliminating Health Disparities with a focus on addressing diverse representation in research on Down syndrome (R21 Clinical Trial Optional)

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Topics: Craniofacial Skeletal Biology & Pathobiology, Oral Health Disparities & Inequities

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Notice of Special Interest (NOSI): HEAL Initiative: Clinical Translation of Diagnostic and Therapeutic Devices via Blueprint MedTech

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR), Technology Development

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HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)

More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance in the prescription of opioids for chronic pain despite their poor ability to improve function and high addiction liability. This contributed to a significant and alarming epidemic of opioid overdose deaths and addictions. Innovative scientific solutions to develop alternative pain treatment options are thus critically needed. Through targeted research efforts, the NIH HEAL Initiative aims to support the development of safe and effective devices to treat pain with little or no addiction liability. This funding opportunity announcement (FOA) is designed to support interdisciplinary research teams of multiple PD/PIs to investigate the mechanism of action of pain relief by medical devices with the overall goal of optimizing therapeutic outcomes for FDA-approved or -cleared technologies. Program teams are expected to accomplish goals that require considerable synergy and collaborative interactions. Teams must leverage appropriate multi-disciplinary expertise to develop new principles and methods for experimentation, analysis, and interpretation. Teams are encouraged to consider objectives that will produce major advances in the field of pain relief by medical devices.

Contact:

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED) (U01 Clinical Trial Not Allowed)

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Topics: National Dental Practice-Based Research Network

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Notice of Special Interest (NOSI): Promoting Mechanistic Research on Therapeutic and Other Biological Properties of Minor Cannabinoids and Terpenes

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Topics: Clinical Research & Clinical Trials, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of NIDCR Participation in RFA-CA-22-040, The Early Detection Research Network: Biomarker Characterization Centers (U2C Clinical Trial Not Allowed)

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of Special Interest (NOSI): Single-Cell Level Spatiotemporal Mapping of Dental and Craniofacial Embryogenesis

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Topics: Craniofacial & Dental Developmental Biology

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Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Dissemination & Implementation Science, Oral Health Disparities & Inequities

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Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Dissemination & Implementation Science, Oral Health Disparities & Inequities

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HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for Advanced Training in Artificial Intelligence for Precision Nutrition Science Research (AIPrN) Institutional Research Training Programs (T32)

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Topics: Career Development, Research Training & Fellowships

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Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3, Clinical Trials Required)

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Topics: Clinical Research & Clinical Trials, Oral Health Disparities & Inequities, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations

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Topics: Behavioral & Social Science, Oral Health Disparities & Inequities

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Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Dissemination & Implementation Science

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Notice of Special Interest (NOSI): Stimulating Research to Understand and Address Hunger, Food and Nutrition Insecurity

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Topics: Clinical Research & Clinical Trials, Oral Health Disparities & Inequities

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Notice to Extend Expiration Date for PAR-20-277: Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Clinical Trial Not Allowed)

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Topics: Gene Discovery, Genomics & Multi-Omics Analysis, Oral, Oropharyngeal & Salivary Gland Cancers

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Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities

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Topics: Dissemination & Implementation Science, Oral Health Disparities & Inequities

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Notice of Special Interest (NOSI): Availability of Administrative Supplements for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project

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Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Mineralized Tissues & Mineralization, Parent Announcements & Trans-NIH Announcements

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Notice of Special Interest (NOSI): Climate Change and Health

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Topics: Behavioral & Social Science, Epidemiology, Oral Health Disparities & Inequities

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Notice of Special Interest (NOSI): Developing Academic Research Enhancement Award (AREA) and Research Enhancement Award Program (REAP) for Institutions with an emphasis on Down syndrome research (R15 Clinical Trial Not Allowed)

Contact:

Topics: Parent Announcements & Trans-NIH Announcements

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Notice of Intent to Publish a Funding Opportunity Announcement for Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track R42 Clinical Trial Not Allowed)

Contact:

Topics: Dental Materials & Biomaterials

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Notice of Intent to Publish a Funding Opportunity Announcement for Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (R61/R33 Clinical Trial Not Allowed)

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Topics: Dental Materials & Biomaterials

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Notice of Intent to Publish a Funding Opportunity Announcement for Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track - R44 Clinical Trial Not Allowed)

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Topics: Dental Materials & Biomaterials

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Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project

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Topics: Parent Announcements & Trans-NIH Announcements

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Notice of Special Interest (NOSI): Mentored Career Development Awards to Foster the Careers of Investigators Pursuing Research Related to Down syndrome as Part of the INCLUDE Project

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Topics: Career Development, Research Training & Fellowships

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Notice of Special Interest (NOSI): Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship Awards to Support Training in Research Related to Down Syndrome as Part of the INCLUDE Project

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Topics: Career Development, Research Training & Fellowships

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Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

Contact:

Topics: Dissemination & Implementation Science

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Notice of Change to PAR-20-238, "Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)"

Contact:

Topics: Oral Health Disparities & Inequities

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Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)

The Clinical and Translational Science Award (CTSA) Program Collaborative and Innovative Acceleration Award (CCIA) supports synergistic activities that accelerate the translational research process through collaboration and innovation. This funding opportunity announcement (FOA) invites applications to develop, demonstrate and disseminate innovative solutions to transform the field of translational science by addressing the inefficiencies that are common across diseases and bringing more interventions to all people more quickly through collaborative science among the CTSA Program hubs, NIH Institutes, Centers, Offices (ICOs) and/or external stakeholders.

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Topics: Parent Announcements & Trans-NIH Announcements

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NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed)

Contact:

Topics: Bioinformatics, Computational Biology & Data Science, Epidemiology

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Short-term Mentored Career Enhancement Award in Dental, Oral, and Craniofacial Research for Mid-Career and Senior Investigators (K18- Independent Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

Contact:

Topics: Dissemination & Implementation Science

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Understanding the Basic Mechanisms of Immune-related Adverse Events (irAEs) in Cancer Immunotherapy

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Topics: Career Development, Oral Immunology, Immunopathology & Immunotherapy, Oral, Oropharyngeal & Salivary Gland Cancers, Research Training & Fellowships

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Notice of Special Interest: Achieving Tissue Robustness Through Harnessing Immune System Plasticity

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Topics: Oral Immunology, Immunopathology & Immunotherapy

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Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)

The overall goal of the Fogarty International Center (FIC) HIV Research Training Program is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research on the evolving HIV epidemic in their countries.This FOA encourages collaborative applications from U.S. and LMIC institutions to support training to achieve technical, administration and financial management expertise required for one of the six research infrastructure functions considered critical to a successful high quality research environment:Research administration and management;Research integrity oversight;Ethical review of research for the protection of human subjects;Laboratory animal welfare oversightHealth sciences library and information services; andInformation and communications technology systems (ICT) for researchResearch infrastructure training programs will maximize previous investments and further strengthen the LMIC institution's research capabilities, and provide more accessible research infrastructure training opportunities to others in their own country and in other LMICs.

Contact:

Topics: Career Development, HIV/AIDS & Oral Health, Research Training & Fellowships

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Planning Grant for Fogarty HIV Research Training Program for Low- and Middle-Income Country Institutions (D71 Clinical Trial Not Allowed)

The Fogarty HIV Research Training Program supports research training that strengthens HIV research capacity of institutions in low-and middle-income countries (LMICs). This FOA offers an opportunity for LMIC institutions to submit a planning grant application to prepare to participate in the Fogarty HIV Research Training Program.These applications must propose a plan to develop a research training program and the subsequent application that will be submitted in response to the companion D43 FOA (PAR-19-283). The planned research training program should strengthen research capacity in a defined high priority HIV scientific area (NOT-OD-15-137) at an LMIC institution(s).

Contact:

Topics: Career Development, HIV/AIDS & Oral Health, Research Training & Fellowships

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Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications for research training programs to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research relevant to the evolving HIV epidemic in their country. This FOA can support training for conducting research in a broad range of HIV research areas across HIV prevention, treatment, care, and quality of life continuum. This includes basic, epidemiologic, clinical, behavioral and social sciences, community-based, implementation, operations, health services, and health systems research. Cross-disciplinary research as well as HIV associated comorbidities and coinfections affecting the HIV epidemic will be supported under this FOA. An application should focus the proposed training program to strengthen research capacity in a defined high priority HIV scientific area aligned with NIH HIV/AIDS research priorities (NOT-OD-20-018) at a specific LMIC institution and collaborating LMIC partner institutions.

Contact:

Topics: Career Development, HIV/AIDS & Oral Health, Research Training & Fellowships

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Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed)

Contact:

Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral & Comprehensive Health, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Periodontal Diseases, Salivary Biology & Dysfunction, Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health

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Notice of Participation of Additional NIH Institutes and Centers in PAR-20-153: Science Education Partnership Awards (SEPA) (R25-Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Notice of Special Interest (NOSI): Administrative Supplements for Research on Womens Health in the IDeA States

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Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Career Development, Clinical Research & Clinical Trials, Common Fund Programs, Conferences & Meetings, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, National Dental Practice-Based Research Network, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Periodontal Diseases, Salivary Biology & Dysfunction, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Research Training & Fellowships, Women's Health

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Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed)

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) is soliciting Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the nations research workforce. Individuals from diverse backgrounds, including those from underrepresented groups and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome.

Contact:

Topics: Dissemination & Implementation Science

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Notice to Include Additional Application Due Dates for NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00)

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Topics: Career Development, Research Training & Fellowships

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Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional)

This funding opportunity announcement (FOA) is a reissue due to an omission of TRAINING RECORD review questions in Section V. This FOA encourages applications for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) D43 program for institutional research training programs in low-and middle-income countries (LMICs, as defined by the World Bank classification system). Applications may be for collaborations between institutions in the U.S and an eligible LMIC or may involve just LMIC institutions if there is a previous track record of externally funded research and/or research training programs by the lead LMIC institution. The proposed institutional research training program is expected to sustainably strengthen the NCD research capacity of the LMIC institutions, and to train in-country experts to develop and conduct research on NCDs across the lifespan, with the long-range goal of developing and implementing evidence-based interventions relevant to their countries. The main focus of research training covered in the application must be relevant to the interests of at least one of the participating NIH ICs as stated by each in this FOA. Other NCD topics may be included as secondary and complementary focus areas. This Funding Opportunity Announcement (FOA) allows support of trainees as the lead investigator of an independent clinical trial; or a separate ancillary study to an existing trial; or to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

Contact:

Topics: Global Health

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NIDCR Notice of Participation in PAR-20-076, "Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)"

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Topics: Career Development, Research Training & Fellowships

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Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. The R21 FOA is intended to encourage exploratory projects that are at an early conceptual stage feasibility study (inception through preliminary development) to demonstrate the core functional capabilities of the proposed approach. The proposed projects may involve considerable risk and should be aimed at producing breakthroughs in microbial-based cancer therapy, imaging, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy.

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R01 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy. (link to OCCAM)

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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NIDCR Mentored Career Development Award to Promote Diversity (K01 Independent Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Mentored Career Development Award to Promote Diversity (K01 Independent Basic Experimental Studies with Humans Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Mentored Career Development Award to Promote Diversity (K01 Clinical Trial Required)

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Topics: Career Development, Research Training & Fellowships

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Notice of Intent to Publish a Funding Opportunity Announcement for Diagnostic Centers of Excellence (X01 Clinical Trial Not Allowed)

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Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Gene Discovery, Genomics & Multi-Omics Analysis

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Notice of Intent to Publish a Funding Opportunity Announcement for a Data Management and Coordinating Center for Diagnostic Centers of Excellence (U2C Clinical Trial Not Allowed)

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Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Gene Discovery, Genomics & Multi-Omics Analysis

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Notice of Information Reissuance of PA-18-932 Increasing Uptake of Evidence-Based Screening in Diverse Adult Populations (R01 Clinical Trial Optional) as a Notice of Special Interest (NOSI)

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Topics: Dissemination & Implementation Science, Epidemiology

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Notice of Clarification for PAR-19-164 "Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)"

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Topics: Career Development, Research Training & Fellowships

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Notice of Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in RFA-MD-22-004 Innovations for Healthy LivingImproving Minority Health and Eliminating Health Disparities (R43/R44- Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Notice of Technical Assistance Webinar for RFA-AR-22-009, HEAL Initiative: Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)

The purpose of this engineering-oriented funding opportunity announcement (FOA) is to encourage submissions of exploratory/developmental Bioengineering Research Grant (EBRG) applications to demonstrate feasibility and potential utility of new capabilities or improvements in quality, speed, efficacy, operability, costs, and/or accessibility of solutions to problems in basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility.

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Notice to Extend Eligibility for Submission of Pathway to Independence Award Applications (K99/R00) to NIDCR due to Covid-19 disruptions

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Basic Experimental Studies Involving Humans Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Basic Experimental Studies Involving Humans Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. Specifically, the focus of this FOA is on the basic science discovery of targets in the peripheral nervous system, central nervous system, immune system or other tissues in the body that can be used to develop treatments that have minimal side effects and little to no abuse/addiction liability. Research supported by this FOA must include rigorous validation studies to demonstrate the robustness of the target as a pain treatment target. This will lower the risk of adopting the target in translational projects to develop small molecules, biologics, natural substances, or devices that interact with this target for new pain treatments. Translational research to develop new medical devices are not the focus of this FOA. Basic science studies of pain and related systems in the body are responsive to this FOA and are encouraged in the context of novel pain therapeutic target discovery. This FOA is not specific for any one or group of pain conditions. Projects to identify novel targets for acute pain, chronic pain, migraine, other headache disorders, osteoarthritis, diabetic neuropathy, chemotherapy-induced neuropathy, sickle-cell pain, post stroke pain, etc. will be considered. Projects to identify novel targets for a combination of chronic overlapping pain conditions or for specific pathological conditions will be considered. Projects that seek to identify novel targets in specific populations such as women, children, older adults or other underrepresented groups will also be responsive to this FOA.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Information: Multi-Institute Interest in Pain Research

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Topics: Clinical Research & Clinical Trials, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN) (UC2 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Advancing Health Equity in Pain and Comorbidities (R61/R33 Clinical Trial Required)

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Topics: Oral Health Disparities & Inequities, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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