Notices of Funding Opportunities

The table below lists all active NIDCR Notices of Funding Opportunitites (NOFOs). Use the filters to sort by funding type, topic, or activity code. Use the search box to find funding opportunities that include specific keywords. Click on title to see more details.

 

287 Results
Title Release Date Expiration Date
Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed)

The purpose of this Academic Research Enhancement Award (AREA) for Undergraduate-Focused Institutions is to support small scale research grants at institutions that do not receive substantial funding from the NIH, with an emphasis on providing biomedical research experiences primarily for undergraduate students, and enhancing the research environment at these applicant institutions. Eligible institutions must award baccalaureate science degrees, and have received less than 6 million dollars per year of NIH support (total costs) in 4 of the last 7 fiscal years.

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Topics: Parent Announcements & Trans-NIH Announcements

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Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)

The National Institutes of Health (NIH) and the Centers for Disease Control and Prevention (CDC) hereby notify Small Business Concerns (SBCs) holding Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants that funds are available for administrative supplements to improve the diversity of the research workforce by recruiting and supporting students, postdoctorates, and eligible investigators from groups that have been shown to be nationally underrepresented in health-related research or in the SBIR and STTR programs. This supplement opportunity is also available to PD(s)/PI(s) of research grants who are or become disabled and need additional support to accommodate their disability in order to continue to work on the research project. Administrative supplements must support work within the scope of the original project. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial. Applicants to this FOA are permitted to propose research experience in a clinical trial led by a mentor or co-mentor.

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Topics: Small Business (SBIR/STTR)

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Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)

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Topics: Parent Announcements & Trans-NIH Announcements

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Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed)

The purpose of this funding opportunity announcement is to encourage collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science.

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Topics: Dental Materials & Biomaterials, Tissue Engineering & Regenerative Medicine

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Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage investigators to pursue translational activities and clinical feasibility studies to advance the development of therapeutic, and diagnostic devices for disorders that affect the nervous or neuromuscular systems. Activities supported in this program include implementation of clinical prototype devices, non-clinical safety and efficacy testing, design verification and validation activities, obtaining an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, as well as a subsequent clinical feasibility study. The clinical study is expected to provide information about the device function or final design that cannot be practically obtained through additional non-clinical assessments (e.g., bench top or animal studies) due to the novelty of the device or its intended use. This FOA is a milestone-driven cooperative agreement program and will involve participation of NIH program staff in negotiating the final project plan before award and monitoring of research progress. Participants in Blueprint MedTech receive funding for all activities to be conducted in their own laboratories. In addition, applicants will collaborate with NIH-funded consultants to receive assistance with specialty areas including regulatory, reimbursement, intellectual property, commercialization, and strategic partnerships. Participants can also augment their project with NIH contract research organizations that specialize in large animal testing, sterilization testing, biocompatibility assessment, manufacturing, and medical monitoring. Individuals, institutions, or businesses developing their own devices or that already have established collaborations with device manufacturers are welcome to apply directly to this FOA or any of the companion opportunities. For more information see BP MedTech website.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional)

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Topics: Career Development, Research Training & Fellowships

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Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)

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Topics: Gene Discovery, Genomics & Multi-Omics Analysis

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Centers for AIDS Research (P30 Clinical Trial Not Allowed)
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional)

The National Institutes of Health (NIH) hereby notify recipient organizations holding specific types of NIH grants, listed in the full Funding Opportunity Announcement (FOA), that applications for change of recipient organization may be submitted to this FOA. This assumes such a change is programmatically permitted for the particular grant. Applications for change of recipient organization are considered prior approval requests (as described in Section 8.1.2.7 of the NIH Grants Policy Statement) and will be routed for consideration directly to the Grants Management Specialist named in the current award. Although requests for change of recipient organization may be submitted through this FOA, there is no guarantee that an award will be transferred to the new organization. All applicants are encouraged to discuss potential requests with the awarding IC before submission.

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Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Career Development, Clinical Research & Clinical Trials, Common Fund Programs, Conferences & Meetings, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, National Dental Practice-Based Research Network, Oral & Comprehensive Health, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Periodontal Diseases, Salivary Biology & Dysfunction, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Research Training & Fellowships

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Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) (D43 Clinical Trial Optional)

This funding opportunity announcement (FOA) is a reissue due to an omission of TRAINING RECORD review questions in Section V. This FOA encourages applications for the Chronic, Non-Communicable Diseases and Disorders Across the Lifespan: Fogarty International Research Training Award (NCD-LIFESPAN) D43 program for institutional research training programs in low-and middle-income countries (LMICs, as defined by the World Bank classification system). Applications may be for collaborations between institutions in the U.S and an eligible LMIC or may involve just LMIC institutions if there is a previous track record of externally funded research and/or research training programs by the lead LMIC institution. The proposed institutional research training program is expected to sustainably strengthen the NCD research capacity of the LMIC institutions, and to train in-country experts to develop and conduct research on NCDs across the lifespan, with the long-range goal of developing and implementing evidence-based interventions relevant to their countries. The main focus of research training covered in the application must be relevant to the interests of at least one of the participating NIH ICs as stated by each in this FOA. Other NCD topics may be included as secondary and complementary focus areas. This Funding Opportunity Announcement (FOA) allows support of trainees as the lead investigator of an independent clinical trial; or a separate ancillary study to an existing trial; or to gain research experience in a clinical trial led by another investigator, as part of their research and career development.

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Topics: Global Health

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Continuation of Temporary Extension of Eligibility for the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) During the COVID-19 Pandemic

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Topics: Career Development, Research Training & Fellowships

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Continuation or Revision of NIDCR Clinical Trial Implementation Cooperative Agreement (UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials

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Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

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Topics: Dissemination & Implementation Science

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Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of the Institutes/Centers listed above.

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Topics: Dissemination & Implementation Science

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Effectiveness of School-Based Health Centers to Advance Health Equity (R01 Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)

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Topics: Bioinformatics, Computational Biology & Data Science

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Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)

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Topics: Bioinformatics, Computational Biology & Data Science, Gene Discovery, Genomics & Multi-Omics Analysis

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Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)

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Topics: Bioinformatics, Computational Biology & Data Science, Gene Discovery, Genomics & Multi-Omics Analysis

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Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed)

The purpose of this engineering-oriented funding opportunity announcement (FOA) is to encourage submissions of exploratory/developmental Bioengineering Research Grant (EBRG) applications to demonstrate feasibility and potential utility of new capabilities or improvements in quality, speed, efficacy, operability, costs, and/or accessibility of solutions to problems in basic biomedical, pre-clinical, or clinical research, clinical care delivery, or accessibility.

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Extramural Clinical Research Loan Repayment Program for Individuals from Disadvantaged Backgrounds (LRP-IDB)

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Topics: Research Training & Fellowships

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Extramural Loan Repayment Program for Clinical Researchers (LRP-CR)

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Topics: Research Training & Fellowships

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Extramural Loan Repayment Program for Contraception and Infertility Research (LRP-CIR)

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Topics: Research Training & Fellowships

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Extramural Loan Repayment Program for Health Disparities Research (LRP-HDR)

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Topics: Research Training & Fellowships

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Extramural Loan Repayment Program for Pediatric Research (LRP-PR)

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Topics: Research Training & Fellowships

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Extramural Loan Repayment Program for Research in Emerging Areas Critical to Human Health (LRP-REACH)

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Topics: Research Training & Fellowships

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Fogarty HIV Research Training Program for Low-and Middle-Income Country Institutions (D43 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications for research training programs to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research relevant to the evolving HIV epidemic in their country. This FOA can support training for conducting research in a broad range of HIV research areas across HIV prevention, treatment, care, and quality of life continuum. This includes basic, epidemiologic, clinical, behavioral and social sciences, community-based, implementation, operations, health services, and health systems research. Cross-disciplinary research as well as HIV associated comorbidities and coinfections affecting the HIV epidemic will be supported under this FOA. An application should focus the proposed training program to strengthen research capacity in a defined high priority HIV scientific area aligned with NIH HIV/AIDS research priorities (NOT-OD-20-018) at a specific LMIC institution and collaborating LMIC partner institutions.

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Topics: Career Development, HIV/AIDS & Oral Health, Research Training & Fellowships

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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (Independent Basic Experimental Studies with Humans Required)

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Topics: Research Training & Fellowships

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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (K99/R00 Independent Clinical Trial Not Allowed)

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Topics: Research Training & Fellowships

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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Basic Experimental Studies with Humans Required)

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Topics: Research Training & Fellowships

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HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR)

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HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. Specifically, the focus of this FOA is on the basic science discovery of targets in the peripheral nervous system, central nervous system, immune system or other tissues in the body that can be used to develop treatments that have minimal side effects and little to no abuse/addiction liability. Research supported by this FOA must include rigorous validation studies to demonstrate the robustness of the target as a pain treatment target. This will lower the risk of adopting the target in translational projects to develop small molecules, biologics, natural substances, or devices that interact with this target for new pain treatments. Translational research to develop new medical devices are not the focus of this FOA. Basic science studies of pain and related systems in the body are responsive to this FOA and are encouraged in the context of novel pain therapeutic target discovery. This FOA is not specific for any one or group of pain conditions. Projects to identify novel targets for acute pain, chronic pain, migraine, other headache disorders, osteoarthritis, diabetic neuropathy, chemotherapy-induced neuropathy, sickle-cell pain, post stroke pain, etc. will be considered. Projects to identify novel targets for a combination of chronic overlapping pain conditions or for specific pathological conditions will be considered. Projects that seek to identify novel targets in specific populations such as women, children, older adults or other underrepresented groups will also be responsive to this FOA.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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HEAL Initiative: EPPIC-Net Pain Research Asset Application (OT2)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)

More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance in the prescription of opioids for chronic pain despite their poor ability to improve function and high addiction liability. This contributed to a significant and alarming epidemic of opioid overdose deaths and addictions. Innovative scientific solutions to develop alternative pain treatment options are thus critically needed. Through targeted research efforts, the NIH HEAL Initiative aims to support the development of safe and effective devices to treat pain with little or no addiction liability. This funding opportunity announcement (FOA) is designed to support interdisciplinary research teams of multiple PD/PIs to investigate the mechanism of action of pain relief by medical devices with the overall goal of optimizing therapeutic outcomes for FDA-approved or -cleared technologies. Program teams are expected to accomplish goals that require considerable synergy and collaborative interactions. Teams must leverage appropriate multi-disciplinary expertise to develop new principles and methods for experimentation, analysis, and interpretation. Teams are encouraged to consider objectives that will produce major advances in the field of pain relief by medical devices.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Technology Development

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HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

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Topics: Clinical Research & Clinical Trials, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to develop clinical-grade prototypes intended for use as safe, effective, and non-addictive device-based technologies and approaches to treat pain. The goal of the program is to demonstrate treatment using credible neural targets for device-based interventions and/or diagnostics for pain, building upon the latest mechanistic knowledge about the anatomy and physiology of central, spinal, and peripheral pathways involved in pain. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use.

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Technology Development

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HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 - Clinical Trial Optional)

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional)
In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains Exhibiting Embryonic or Perinatal Lethality or Subviability (R01 Clinical Trial Not Allowed)

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Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology

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INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Infrastructure Development Training Programs for Critical HIV Research at Low-and Middle-Income Country Institutions (G11 Clinical Trials Not Allowed)

The overall goal of the Fogarty International Center (FIC) HIV Research Training Program is to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research on the evolving HIV epidemic in their countries.This FOA encourages collaborative applications from U.S. and LMIC institutions to support training to achieve technical, administration and financial management expertise required for one of the six research infrastructure functions considered critical to a successful high quality research environment:Research administration and management;Research integrity oversight;Ethical review of research for the protection of human subjects;Laboratory animal welfare oversightHealth sciences library and information services; andInformation and communications technology systems (ICT) for researchResearch infrastructure training programs will maximize previous investments and further strengthen the LMIC institution's research capabilities, and provide more accessible research infrastructure training opportunities to others in their own country and in other LMICs.

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Topics: Career Development, HIV/AIDS & Oral Health, Research Training & Fellowships

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Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities, Small Business (SBIR/STTR), Technology Development

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Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed)

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Topics: Parent Announcements & Trans-NIH Announcements

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Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Intervention Research to Improve Native American Health (R21 Clinical Trials Optional)

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Topics: Oral Health Disparities & Inequities

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Intervention Research to Improve Native American Health (R34 Clinical Trial Optional)

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Topics: Oral Health Disparities & Inequities

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Interventions for Stigma Reduction to Improve HIV/AIDS Prevention, Treatment and Care in Low- and Middle- Income Countries (R01 - Clinical Trial Optional)
Interventions to expand cancer screening and preventive services to ADVANCE health in populations that experience health disparities (R01, Clinical Trial Required)

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Topics: Oral Health Disparities & Inequities, Oral, Oropharyngeal & Salivary Gland Cancers

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INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Research Short Course (R25 Independent Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

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Topics: Behavioral & Social Science, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Epidemiology

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Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional)

The Clinical and Translational Science Award (CTSA) Program Collaborative and Innovative Acceleration Award (CCIA) supports synergistic activities that accelerate the translational research process through collaboration and innovation. This funding opportunity announcement (FOA) invites applications to develop, demonstrate and disseminate innovative solutions to transform the field of translational science by addressing the inefficiencies that are common across diseases and bringing more interventions to all people more quickly through collaborative science among the CTSA Program hubs, NIH Institutes, Centers, Offices (ICOs) and/or external stakeholders.

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Topics: Parent Announcements & Trans-NIH Announcements

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Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH))

The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.

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Topics: Career Development, Research Training & Fellowships

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Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Required)

The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.

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Topics: Career Development, Research Training & Fellowships

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Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 Independent Clinical Trial Not Allowed)

The purpose of the MOSAIC Postdoctoral Career Transition Award to Promote Diversity (K99/R00) program is to support a cohort of early career, independent investigators from diverse backgrounds conducting research in NIH mission areas. The long-term goal of this program is to enhance diversity in the basic biomedical sciences research workforce. The MOSAIC K99/R00 program is designed to facilitate a timely transition of outstanding postdoctoral researchers from diverse backgrounds (e.g., see NIHs Interest in Diversity) from their mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions at research-intensive institutions. The MOSAIC K99/R00 program will provide independent NIH research support during this transition to help awardees launch competitive, independent research careers. Additionally, MOSAIC K99/R00 scholars will be part of organized scientific cohorts that will be expected to participate in mentoring, networking, and professional development activities coordinated by MOSAIC Institutionally-Focused Research Education Award to Promote Diversity (UE5) grantees.

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Topics: Career Development, Research Training & Fellowships

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Measures and Methods to Advance Research on Minority Health and Health Disparities-Related Constructs (R01 Clinical Trial Not Allowed)

The purpose of this Funding Opportunity Announcement (FOA) is to support research that will advance the measurement and assessment of complex constructs relevant to minority health and health disparities.

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Topics: Oral Health Disparities & Inequities

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Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R01 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy. (link to OCCAM)

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Microbial-based Cancer Imaging and Therapy - Bugs as Drugs (R21 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. The R21 FOA is intended to encourage exploratory projects that are at an early conceptual stage feasibility study (inception through preliminary development) to demonstrate the core functional capabilities of the proposed approach. The proposed projects may involve considerable risk and should be aimed at producing breakthroughs in microbial-based cancer therapy, imaging, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy.

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Topics: Oral, Oropharyngeal & Salivary Gland Cancers

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Multi-sectoral preventive interventions that address social determinants of health in populations that experience health disparities (UG3/UH3, Clinical Trial Required)
Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional)
Multidisciplinary Studies of HIV/AIDS and Aging (R21 Clinical Trial Optional)
Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)

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Topics: Clinical Research & Clinical Trials, Oral Health Disparities & Inequities

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NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Dissemination & Implementation Science

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NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

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Topics: Behavioral & Social Science, Oral Health Disparities & Inequities

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NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Basic Experimental Studies Involving Humans Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dentist Scientist Career Transition Award for Intramural Investigators (K22 Clinical Trial Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Basic Experimental Studies Involving Humans Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials

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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials

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NIDCR Mentored Career Development Award to Promote Diversity (K01 Clinical Trial Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Mentored Career Development Award to Promote Diversity (K01 Independent Basic Experimental Studies with Humans Required)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Mentored Career Development Award to Promote Diversity (K01 Independent Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Mentoring Network to Promote a Diverse Dental, Oral and Craniofacial Research Workforce (UE5 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIDCR Notice of Participation in PA-24-141 "NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)"

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Topics: Parent Announcements & Trans-NIH Announcements

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NIDCR Notice of Participation in PAR-20-076, "Jointly Sponsored Ruth L. Kirschstein National Research Service Award Institutional Predoctoral Training Program in the Neurosciences (T32 Clinical Trial Not Allowed)"

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Topics: Career Development, Research Training & Fellowships

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NIDCR Notice of Participation in PAR-23-109, “NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)”

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Topics: Career Development, Research Training & Fellowships

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NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)"

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Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Periodontal Diseases, Salivary Biology & Dysfunction, Sjogren’s Disease, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health

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NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)"

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Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Periodontal Diseases, Salivary Biology & Dysfunction, Sjogren’s Disease, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health

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NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
NIDCR Research Grants for Analyses of Existing Genomics Data (R01) (Clinical Trial Not Allowed)

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Topics: Bioinformatics, Computational Biology & Data Science

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NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)

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Topics: Bioinformatics, Computational Biology & Data Science

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NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed)

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Topics: Bioinformatics, Computational Biology & Data Science, Epidemiology

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NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)

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Topics: Career Development, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Research Training & Fellowships

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NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) (R25 Clinical Trial Not Allowed)

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Topics: Career Development, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Research Training & Fellowships

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NIH Blueprint for Neuroscience Research: Request for Information (RFI) on Neuroimmune Interactions in the Healthy CNS

Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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NIH Blueprint for Neuroscience Research: Request for Information (RFI) on the NIH Toolbox Assessments Conference

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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology

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NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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NIH Science Education Partnership Award (SEPA) (R25 - Clinical Trial Not Allowed)

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Topics: Career Development, Research Training & Fellowships

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