Notices of Funding Opportunities
The table below lists all active NIDCR Notices of Funding Opportunitites (NOFOs). Use the filters to sort by funding type, topic, or activity code. Use the search box to find funding opportunities that include specific keywords. Click on title to see more details.
28 Results
| Title | Release Date | Expiration Date |
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Pilot Projects Enhancing Utility and Usage of Common Fund Data Sets (R03 Clinical Trial Not Allowed)
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Topics: Bioinformatics, Computational Biology & Data Science, Common Fund Programs |
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HEAL Initiative: Studies to Enable Analgesic Discovery (R61/R33 - Clinical Trial Not Allowed)
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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Technologies and Assays for Therapeutic Genome Editing INDs (U01, Clinical Trial Not Allowed)
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NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional)
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NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional)
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NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional)
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NIH Director’s Early Independence Awards (DP5 Clinical Trial Optional)
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Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional)
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Topics: Oral Health Disparities & Inequities, Small Business (SBIR/STTR), Technology Development |
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Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
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Topics: Oral Health Disparities & Inequities, Small Business (SBIR/STTR), Technology Development |
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Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional)
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INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)
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NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
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Topics: Career Development, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Research Training & Fellowships |
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HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
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Topics: Clinical Research & Clinical Trials, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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HEAL Initiative: Understanding Individual Differences in Human Pain Conditions (R01 - Clinical Trial Optional)
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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) (R25 Clinical Trial Not Allowed)
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Topics: Career Development, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Research Training & Fellowships |
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HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)
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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Technology Development |
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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (K99/R00 Independent Clinical Trial Not Allowed)
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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research (Independent Basic Experimental Studies with Humans Required)
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HEAL Initiative Advanced Postdoctoral-to-Independent Career Transition Award in PAIN and SUD Research to Promote Diversity (K99/R00 Independent Basic Experimental Studies with Humans Required)
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The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional)
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Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Oral Health Disparities & Inequities, Women's Health |
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HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)
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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR) |
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HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Small Business (SBIR/STTR) |
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HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to develop clinical-grade prototypes intended for use as safe, effective, and non-addictive device-based technologies and approaches to treat pain. The goal of the program is to demonstrate treatment using credible neural targets for device-based interventions and/or diagnostics for pain, building upon the latest mechanistic knowledge about the anatomy and physiology of central, spinal, and peripheral pathways involved in pain. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use. Contact:Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Technology Development |
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HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)
More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance in the prescription of opioids for chronic pain despite their poor ability to improve function and high addiction liability. This contributed to a significant and alarming epidemic of opioid overdose deaths and addictions. Innovative scientific solutions to develop alternative pain treatment options are thus critically needed. Through targeted research efforts, the NIH HEAL Initiative aims to support the development of safe and effective devices to treat pain with little or no addiction liability. This funding opportunity announcement (FOA) is designed to support interdisciplinary research teams of multiple PD/PIs to investigate the mechanism of action of pain relief by medical devices with the overall goal of optimizing therapeutic outcomes for FDA-approved or -cleared technologies. Program teams are expected to accomplish goals that require considerable synergy and collaborative interactions. Teams must leverage appropriate multi-disciplinary expertise to develop new principles and methods for experimentation, analysis, and interpretation. Teams are encouraged to consider objectives that will produce major advances in the field of pain relief by medical devices. Contact:Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed)
The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) is soliciting Transformative Research Award applications to support individual scientists or groups of scientists proposing groundbreaking, exceptionally innovative, original, and/or unconventional research that has the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies related to Down syndrome. For the program to support the best possible researchers and research, applications are sought which reflect the full diversity of the nations research workforce. Individuals from diverse backgrounds, including those from underrepresented groups and from the full spectrum of eligible institutions in all geographic locations are strongly encouraged to apply to this Funding Opportunity Announcement. Applications are welcome in all topics relevant to Down syndrome-related research or its co-occurring conditions. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in research related to Down syndrome. Contact:Topics: Dissemination & Implementation Science |
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HEAL Initiative: Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R01 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to promote the discovery and validation of novel therapeutic targets to facilitate the development of pain therapeutics. Specifically, the focus of this FOA is on the basic science discovery of targets in the peripheral nervous system, central nervous system, immune system or other tissues in the body that can be used to develop treatments that have minimal side effects and little to no abuse/addiction liability. Research supported by this FOA must include rigorous validation studies to demonstrate the robustness of the target as a pain treatment target. This will lower the risk of adopting the target in translational projects to develop small molecules, biologics, natural substances, or devices that interact with this target for new pain treatments. Translational research to develop new medical devices are not the focus of this FOA. Basic science studies of pain and related systems in the body are responsive to this FOA and are encouraged in the context of novel pain therapeutic target discovery. This FOA is not specific for any one or group of pain conditions. Projects to identify novel targets for acute pain, chronic pain, migraine, other headache disorders, osteoarthritis, diabetic neuropathy, chemotherapy-induced neuropathy, sickle-cell pain, post stroke pain, etc. will be considered. Projects to identify novel targets for a combination of chronic overlapping pain conditions or for specific pathological conditions will be considered. Projects that seek to identify novel targets in specific populations such as women, children, older adults or other underrepresented groups will also be responsive to this FOA. Contact:Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21 Clinical Trial Not Allowed)
This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. Contact:Topics: Behavioral & Social Science, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Epidemiology |
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HEAL Initiative: EPPIC-Net Pain Research Asset Application (OT2)
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Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |