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Caries Susceptibility

Caries Susceptibility

Title:
Caries Susceptibility

Description:
Non-parametric linkage results summary (presented as negative logs of the p-values) of the 2 genome-wide scans for low caries susceptibility loci (DMFT categories 1 and 2, assigned as 'affected') and high caries susceptibility loci (DMFT categories 3 and 4, assigned as 'affected') in 46 families. Bars indicate the –log linear of the most significant p values in each chromosome. In addition to chromosome X (p = 0.00005), chromosomes 5 (p = 0.001), 6 (p = 0.009), 13 (p = 0.006), and 22 (p = 0.004) presented interesting results. DMFT = Decayed, Missing due to caries, Filled Teeth; single low = singlepoint linkage analysis in low caries susceptibility; multi low = multipoint linkage analysis in low caries susceptibility; single high = single-point linkage analysis in high caries susceptibility; multi high = multipoint linkage analysis in high caries susceptibility.

Credit:
Genome-wide Scan Finds Suggestive Caries Loci. A.R. Vieira, M.L. Marazita and T. Goldstein-McHenry. J Dent Res. 2008 May;87(5):435-9.

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This page last updated: April 18, 2014