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Osr2 Mutant Teeth

Osr2 Mutant Teeth

Osr2 Mutant Teeth

Mice lacking the Osr2 transcription factor developed supernumerary teeth lingual to their molars. This photo shows a frontal section through the first molar tooth germs in an Osr2 mutant mouse pup at gestational day 18. Black arrowheads point to the mandibular first molar tooth germs, and arrows point to the supernumerary tooth germs lingual to the first molars. "t" labels the tongue

This photograph was provided by Dr. Rulang Jiang,
University of Rochester

For more information on the role of Osr2 in tooth development and patterning, please read the original publication by Zhang et al. (Science 323:1232-1234, 2009).

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This page last updated: February 26, 2014