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Localization of Msb2 in Yeast

Yeast Cells

Title:
Localization of Msb2 in Yeast

Description:
Localization of a signaling mucin GFP fusion in live yeast cells by fluorescence microscopy. Cleavage of the mucin by an aspartyl protease and release of its inhibitory domain is required for signal transduction (MAPK) activation.

Credit:
Vadaie, N., Dionne, H., Nickerson, S.R., Akajagbor, D.S., Krysan, D.J., and Cullen, P.J. (2008) Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast. J. Cell Biology 181: 1073-1081.

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This page last updated: February 26, 2014