James E. Melvin, DDS, PhD, who has been the clinical director in NIDCR’s Division of Intramural Research since 2010, has been appointed the Division’s deputy scientific director. An internationally renowned investigator, Melvin has made landmark contributions to the field of salivary gland physiology. As a senior investigator in the Division’s Secretory Mechanisms and Dysfunction Section, his lab focuses on elucidating the ion transport mechanisms of salivary glands.
“Dr. Melvin’s outstanding leadership during his five-year tenure as clinical director has made a difference in the lives of the patients who visit our dental clinic, and in the lives and careers of the clinical fellows who are trained and mentored here,” said Martha J. Somerman, DDS, PhD. “We are extremely fortunate to have a leader with Dr. Melvin’s versatility to transition from the administration of our clinical research to our basic research program.”
Melvin’s other key accomplishments as clinical director include building support mechanisms and staffing for development, review, and execution of clinical research protocols. In addition, he established an active clinical fellows training program that provides a strong mentored experience grounded in basic research. Melvin also created a competitive K22 grant mechanism to support fellows’ mentored transition to independent research.
Before becoming clinical director, Melvin was professor of pharmacology and physiology in the Center for Oral Biology, School of Medicine and Dentistry at the University of Rochester in New York. He held numerous appointments at the University of Rochester, where he received tenure in 1997 and where he published more than 92 papers.
Melvin received a DDS from Case Western Reserve University in Ohio, earned a PhD in Neurobiology from the University of Rochester in New York, and completed a postdoctoral fellowship at what was then called the National Institute of Dental Research at NIH.