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Clinical Research and Clinical Technologies

​The NIDCR encourages applications proposing development of innovative technologies that could improve the health of people with oral and craniofacial diseases and disorders. The Clinical Research and Clinical Technologies Program supports research aimed at:

  • Developing and testing the safety, efficacy, and/or effectiveness of measures or materials for diagnosing, preventing, or treating dental, oral, and craniofacial conditions and disorders.
  • Using existing biological structures in the oral cavity as a delivery system for local and systemic treatment. 
  • Developing oral devices and materials for monitoring local and systemic conditions.
  • Developing oral health related precision medicine approaches. 
  • Developing methods and tools to detect soft and hard tissue conditions in the oral cavity.
Types of NIDCR-Supported Research

The Clinical Research and Clinical Technologies Program supports basic, translational, and clinical research studies. Research that might be supported includes, but is not limited to:

  • Studies that assess the clinical utility of diagnostic imaging devices for dental caries, periodontal disease, cracked teeth and pulp vitality.
  • Studies that accelerate the clinical implementation of diagnostic imaging devices proven to be superior to existing methods. 
  • Studies for development of specific and sensitive imaging devices for early diagnosis of medical conditions in the head and neck. 
  • Studies to evaluate performance of new and current theranostics (diagnostic-therapeutic) devices for oral and craniofacial diseases and disorders. 
  • Studies of non-invasive and minimally-invasive technologies for diagnosis or treatment of oral and craniofacial diseases and disorders. 
  • Clinical oral health research that implements precision medicine. 
Mechanisms for Support

Investigator-initiated applications in response to NIH parent grant announcements and applications responsive to NIDCR Program Announcements are encouraged.  Please see:

For information on design, planning, or implementation of clinical trials, see “Clinical Trials Program.” 

Additional Information

For further information about the Clinical Research and Clinical Technologies program, please contact:

Gallya Gannot, DMD, PhD 
Director, Clinical Research and Clinical Technologies Program
Center for Clinical Research
Division of Extramural Research 
National Institute of Dental and Craniofacial Research 
6701 Democracy Blvd. 
Room 632, Mail Stop 4878 
Bethesda, MD 20892-4878 
Office: (301) 451-5096

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This page last updated: July 14, 2016