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Clinical Research and Epidemiology

Contact: Dr. Dena Fischer, (301) 594-4876, dena.fischer@nih.gov 

The NIDCR encourages applications proposing patient-oriented and population-based studies of oral and craniofacial diseases and disorders. The Clinical Research and Epidemiology Program supports research aimed at:

 

  • Identifying and characterizing risk and protective factors for the development or progression of oral and craniofacial diseases and disorders;
  • Defining the natural history of oral and craniofacial diseases and disorders;
  • Understanding how genetic, behavioral and environmental factors interact to contribute to oral disease susceptibility;
  • Describing the distribution of oral, dental and craniofacial diseases and disorders;
  • Identifying differences in oral disease distribution among population sub-groups;
  • Determining treatment outcomes for oral, dental and craniofacial diseases and disorders;
  • Clinically characterizing pathways involved in the development of oral and craniofacial diseases and disorders.

Types of NIDCR-Supported Research

The Clinical Research and Epidemiology Program supports cross-sectional descriptive, case-control, prospective cohort and retrospective studies. Examples of studies that might be supported include, but are not limited to:

  • Longitudinal observational studies of the sequelae and impact of oral and craniofacial diseases and disorders;
  • Cohort studies to clinically characterize pathways involved in the pathogenesis of oral and craniofacial diseases and disorders;
  • Observational studies such as patient registries to follow outcomes and identify best practices for treatment of the oral sequelae of cleft lip / cleft palate, head and neck radiation, Sjögren’s syndrome, ectodermal dysplasias or other oral and craniofacial diseases and disorders;
  • Retrospective studies to obtain preliminary data regarding efficacy of different therapies for oral and craniofacial diseases and disorders;
  • Identification and validation of existing and new methods to measure and document oral, dental and craniofacial diseases and disorders;
  • Development of methods to enhance oral disease detection;
  • Investigations of links between biologic, behavioral, environmental, and genetic factors associated with oral and craniofacial diseases and disorders.

The NICDR program supporting clinical trials is described at:
/Research/DER/ClinicalResearch/Pages/ClinTrials.aspx

Mechanisms for support


Investigator-initiated applications in response to NIH parent grant announcements and applications responsive to NIDCR Program Announcements are encouraged.  Please see:

For information on design, planning, or implementation of clinical trials, see “Clinical Trials Program.” 

Additional Information


For further information about the Clinical Research and Epidemiology Program, please contact:

Dena photo_Oct 2014 (2).jpg

 

Dena J. Fischer, D.D.S., M.S.D., M.S. 
Director, Clinical Research and Epidemiology
Center for Clinical Research  
Division of Extramural Research
National Institute of Dental and Craniofacial Research
6701 Democracy Blvd.
Room 637, Mail Stop 4878
Bethesda, MD 20892-4878
Telephone: (301) 594-4876
Email: dena.fischer@nih.gov​​
 


 

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This page last updated: July 24, 2017