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Aditya Sethi, Ph.D.

Research Fellow
Developmental Mechanisms Section


NATIONAL INSTITUTES OF HEALTH/NIDCR
30 CONVENT DRIVE MSC 4326
ROOM 523
BETHESDA MD 20892

Phone: 301-496-1392
Fax: 301-480-5353
E-mail: sethia@mail.nih.gov
 

Biographical Sketch

I attended medical school at the Smt. NHL Municipal Medical College in Ahmedabad, India from 1995 to 2001. I received my Ph.D. in biomedical genetics in 2007 from the University of Rochester, School of Medicine & Dentistry, where I studied gene regulatory network interactions in early embryonic endomesoderm induction in the laboratory of Drs. Robert and Lynne Angerer. As a post-doctoral fellow in Dr. Lynne Angerer’s group, I study how gene regulatory circuits initiate and stabilize segregation of the endoderm and mesoderm from a primordial endomesoderm territory.

Research Interests/Scientific Focus

  • Signaling mechanisms that regulate cell fate decisions
  • Understanding signaling crosstalk in lineage allocation decisions
  • Systems biology approaches to studying embryonic patterning

Selected Publications

  1. Sethi AJ, Wikramanayake, RM, Angerer, RC, Range, RC and Angerer, LM (2012) Sequential Signaling Crosstalk Regulates Endomesoderm Segregation in Sea Urchin Embryos.  Science 335:590, Editor’s Choice, Science Signaling.
  2. Sethi AJ, Angerer RC, Angerer LM. Multi-color labeling in developmental gene regulatory network analysis. Methods in Molecular Biology (in press).
  3. Sethi AJ, Angerer RC, Angerer LM, 2009 Gene Regulatory Network Interactions in Sea Urchin Endomesoderm Induction. PLoS Biology7 (2).  Open Access Article
  4. Nivsarkar M, Sethi AJ, Bapu C, Patel M, Padh H. Involvement of endometrial membrane sulphydryl groups in blastocyst implantation: Sulphydryl groups as a potential target for contraceptive research.  Contraception 64(4): pp 255-9 (2001).

 

 

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This page last updated: February 26, 2014