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Craniofacial Developmental, Cell and Matrix Biology

Exploring fundamental questions concerning the mechanisms of tissue morphogenesis, cellular function, differentiation and cancer, with the goal of preventing and treating craniofacial disorders.

Principal Investigators

  • Bugge, Thomas, Ph.D.

    Pericellular proteolysis in development, tissue homeostasis and disease
  • Collins, Michael T., M.D.
    Biology and physiology of bone and mineral metabolism through clinical and translational studies primarily in rare, monogenic human diseases
  • Hoffman, Matthew, B.D.S., Ph.D.

    Developmental mechanisms underlying progenitor cell fate during salivary gland organogenesis
  • Kulkarni, Ashok, Ph.D.
    Neuroscience; molecular biology and biochemistry; biochemistry
  • Lee, Janice S., D .D.S., M.D., M.S.
    Bone regeneration and stem cell biology, craniofacial congenital anomalies, fibrous dysplasia, and McCune-Albright syndrome
  • Park, Myung Hee, Ph.D.
    Role of polyamines and eIF5A in translation and proliferation in mammalian cells
  • Robey, Pamela Gehron, Ph.D.
    The role of bone marrow stromal cells and skeletal stem cells in skeletal homeostasis, in disease, and in tissue regeneration; membrane type-matrix metalloproteinases in remodeling of bone and associated tissues
  • Tabak, Lawrence A., D.D.S., Ph.D.
    Biosynthesis, structure, and function of glycoproteins, placing a special emphasis on mucin-type O-glycans
  • Ten Hagen, Kelly, Ph.D.
    Protein modification (glycosylation) influence on organ morphogenesis and function
  • Werner, Achim, Ph.D.
    Molecular mechanisms controlling cell-fate choices, especially those involved in neural crest specification
  • Yamada, Kenneth, M.D., Ph.D.
    Mechanisms and regulation of cell-extracellular matrix interactions and their roles in cell migration, cancer invasion, and embryonic development
  • Yamada, Yoshihiko, Ph.D.
    Roles of the extracellular matrix and protein factors in ectodermal development and diseases
  • Young, Marian F., Ph.D.
    Extracellular matrix protein function in the skeleton tissues including bones, teeth, cartilage and tendon

Associated Investigators

  • Weigert, Roberto, Ph.D. ​
    Mechanisms and regulation of membrane trafficking in live animals under physiological and pathological conditions.

All NIDCR Investigators

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This page last updated: July 18, 2017