In Brief:
- Aside from their role as a physical protective barrier, epithelial cells that line the mouth and gums (gingiva) may directly activate the immune system.
- Gingival epithelial cells, rather than immune cells, may be the harbingers of chronic inflammation that lead to gum disease.
Cells that line the mouth, gum (gingival) tissues, skin, lungs, and intestines, so-called epithelial cells, act as a physical barrier to protect the bo