A recent study adds an unexpected twist to what was known about the immune disturbances that allow fungus to take hold in the mouth. The findings could lead to better therapies for fungal infections.
NIDCR immunologist Roxane Tussiwand studies how molecular cues shape the development of immune cells. Her findings could help scientists better understand infectious diseases, cancer, and autoimmune disorders.
In an NIDCR-supported study, scientists set out to develop a better material for regenerating bone in the mouth. Twenty years later, after their research took some twists and turns, they invented an innovative adhesive for oral surgery—inspired by slugs with elements from shellfish and seaweed.
Researchers have discovered a new genetic disorder characterized by developmental delays and malformations of the brain, heart, and facial features. The underlying pathway may be essential for human development and could also underlie other disorders that are present at birth.