NIDCR News 2023

For 25 years, NIDCR scientists have been looking for better ways to treat fibrous dysplasia/McCune-Albright syndrome, a rare disorder of the bones, skin, and endocrine system.

The COVID-19 pandemic thrust NIDCR science into the spotlight. Research on virus biology, detection methods, and more could ready us for future pandemics.

What shapes our faces? Decades’ worth of NIDCR research is enabling scientists to crack the code of facial appearance and craniofacial conditions.

NIDCR scientists found that mice lacking a protein called biglycan developed weak bones that healed poorly from fractures. The findings could inform strategies to better repair fractures and treat disorders marked by bone loss, such as osteoporosis.

An NIDCR-led clinical trial showed promise for treating fibrous dysplasia, a rare skeletal disorder. The medication, denosumab, is the first to reduce the bone-weakening process in the disorder.

Advances in digital technologies and data science hold promise for improving oral health care and enabling personalized treatment.

Scientific advances have not been fully translated into accessible oral health care for communities in need. Improving access to safe, affordable, and holistic medical and dental care can mitigate inequities.