NIDCR News 2019

International study reveals shared genetic links between dental & metabolic diseases


In Brief:

  • In the largest study of its kind, an international group of researchers analyzed oral health and genetic data collected from over 500,000 participants and identified 47 areas of the genome linked to dental caries (tooth decay).
  • The study also revealed that dental caries and periodontitis (gum disease) share certain genetic signatures with characteristics such as smoking, education, personality traits, and
By studying the mechanisms that govern immune tolerance, NIDCR’s Wanjun Chen aims to develop therapies that could block self-destructive immune responses in people who have autoimmune diseases.
NIDCR-supported researchers found pain-related clinical measures predicted development of chronic TMD.
NIDCR researcher Dr. Laura Kerosuo studies how a short-lived clump of cells within the neural crest shapes development.
Your mouth is home to about 700 species of germs, like bacteria, fungus, and more. NIDCR-supported scientists study how some microbes maybe helpful, while others may harm our health.
Regenerative medicine researchers can envision a not-too-distant future when stem cells help to treat periodontal disease, broken jaws, craniofacial defects, and more.
Older adults are keeping more of their natural teeth than in previous decades, and complete tooth loss continues to decline, according to an analysis by NIDCR scientists.

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