NIDCR News 2023

From gene therapy to salivary gland regeneration, NIDCR-supported scientists aim to restore saliva flow for people with diseased or damaged glands.

An experimental drug, encaleret, showed promise for treating autosomal dominant hypocalcemia type 1 in an NIDCR-led trial. The rare genetic disorder, marked by low blood calcium levels, can cause symptoms from muscle cramps to life-threatening seizures.

NIDCR researchers made an unexpected discovery that helps to answer a long-standing mystery tied to a group of stem cells that are key to vertebrate development.

For 25 years, NIDCR scientists have been looking for better ways to treat fibrous dysplasia/McCune-Albright syndrome, a rare disorder of the bones, skin, and endocrine system.
The COVID-19 pandemic thrust NIDCR science into the spotlight. Research on virus biology, detection methods, and more could ready us for future pandemics.

What shapes our faces? Decades’ worth of NIDCR research is enabling scientists to crack the code of facial appearance and craniofacial conditions.

NIDCR scientists found that mice lacking a protein called biglycan developed weak bones that healed poorly from fractures. The findings could inform strategies to better repair fractures and treat disorders marked by bone loss, such as osteoporosis.

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