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Scientists Identify a Culprit for Chronic Itch

A drug that blocks an immune substance called oncostatin M reduced scratching in a mouse model of chronic itch, suggesting a treatment strategy for persistent itchy skin conditions.

Stem Cell Treatment Corrects Skull Shape and Restores Brain Function in Mouse Model of Childhood Disorder

Using stem cells to regenerate parts of the skull, scientists corrected skull shape and reversed learning and memory deficits in young mice with craniosynostosis, a condition estimated to affect 1 in every 2,500 infants born in the United States.

Oral Health in America - February 2022 Bulletin

Section 2A Summary

Oral Health Across the Lifespan: Children

AHEAD (Advancement of Head and Neck Cancer Early Detection Research)

January 2022

Oral and Salivary Cancer Biology Program
Integrative Biology and Infectious Disease Branch
Division of Extramural Research

Goal

The goal of this initiative is to accelerate translation of research to improve early detection of head and neck cancers (HNC). This initiative will encourage development, evaluation, and validation of biomarkers for risk assessment, detection, and molecular diagnosis and prognosis of early HNC.

TMD Collaborative for IMproving PAtient-Centered Translational Research (TMD IMPACT)

January 2022

Neuroscience of Orofacial Pain & Temporomandibular Disorders Program
Integrative Biology and Infectious Diseases Branch
Division of Extramural Research

Oral Health in America - January 2022 Bulletin

Itching for Answers

Recent studies by NIDCR immunologists and neuroscientists indicate that not all itch is created equal, and that treatments tailored to specific kinds of itch may offer more effective relief than a one-size-fits-all approach.

Disarming a Blood-Clotting Protein Prevents Gum Disease in Mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, pointing to a potential treatment avenue for gum disease and other inflammatory conditions.

Tooth Protein Prevents Bone Loss in Mice

NIDCR researchers and colleagues found that a tooth-hardening protein prevents bone loss in mice, which could lead to potential treatments for conditions marked by bone loss, including severe gum disease and osteoporosis.

231st National Advisory Dental & Craniofacial Research Council Meeting

Virtual Event