Notices of Funding Opportunities
The table below lists all active NIDCR Notices of Funding Opportunitites (NOFOs). Use the filters to sort by funding type, topic, or activity code. Use the search box to find funding opportunities that include specific keywords. Click on title to see more details.
305 Results
| Title | Release Date | Expiration Date |
|---|---|---|
Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Planning Studies for Initial Analgesic Development Initial Translational Efforts [Small Molecules and Biologics]
Topics: Parent Announcements & Trans-NIH Announcements, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Notice of Correction to Application Types Allowed for PAR-21-197, NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Contact:
Topics: Behavioral & Social Science, Oral Health Disparities & Inequities |
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Notice of Information: Multi-Institute Interest in Pain Research
Contact:
Topics: Clinical Research & Clinical Trials, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint Neurotherapeutics Network (BPN): Biologic-based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Notice of Intent to Publish a Funding Opportunity Announcement for HEAL Initiative: Developing Quantitative Imaging and Other Relevant Biomarkers of Myofascial Tissues for Clinical Pain Management
Contact:
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Technology Development |
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Notice to Extend Eligibility for Submission of Pathway to Independence Award Applications (K99/R00) to NIDCR due to Covid-19 disruptions
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Notice of Change in Receipt Date for Applications to Harnessing Technologies to Support Oral Health Promotion and Management Outside the Dental Setting (RFA-DE-23-009)
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Notice of Pre-Application Webinar for PAR-24-104 "NIDCR Mentoring Network to Promote a Diverse Dental, Oral and Craniofacial Research Workforce (UE5 Clinical Trial Not Allowed)"
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Notice of Change to PAR-20-238, "Intervention Research to Improve Native American Health (R01 Clinical Trial Optional)"
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Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed)
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Notice to Extend the Expiration Date for PAR-18-656, NIDCR Behavioral and Social Intervention Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
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Notice of Technical Assistance Webinar for RFA-DE-23-012 Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED)
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Notice of NIDCR's Participation in PAR-19-193 "Microbial-based Cancer Therapy-Bugs as Drugs (R01- Clinical Trial Not Allowed)"
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NIH Blueprint for Neuroscience Research: Request for Information (RFI) on Neuroimmune Interactions in the Healthy CNS
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Notice of Clarification for PAR-19-164 "Summer Research Education Experience Program (R25 Clinical Trial Not Allowed)"
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Notice of Intent to Publish a Funding Opportunity Announcement for Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track - R44 Clinical Trial Not Allowed)
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Notice of NIDCR's Participation in PAR-18-830 "The Role of Epitranscriptomics in Development and Disease (R01 - Clinical Trial Not Allowed)"
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Notice of Intent to Reissue PAR-18-845 Electronic Nicotine Delivery Systems (ENDS): Basic Mechanisms of Health Effects (R01 - Clinical Trial Not Allowed) and PAR-18-846 (R21 - Clinical Trial Not Allowed) as a Notice of Special Interest (NOSI)
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Notice of Information Reissuance of PA-18-932 Increasing Uptake of Evidence-Based Screening in Diverse Adult Populations (R01 Clinical Trial Optional) as a Notice of Special Interest (NOSI)
Contact:
Topics: Dissemination & Implementation Science, Epidemiology |
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Notice of Clarification Relevant to Section IV, Application and Submission Information for PAR-20-046 NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)
Contact:
Topics: Bioinformatics, Computational Biology & Data Science, Statistical Analysis & Data Science |
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RESCINDED - NIDCR Policy on Applications for Investigator-Initiated Clinical Trials
Contact:
Topics: Behavioral & Social Science, Clinical Research & Clinical Trials |
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Notice of Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in PAR-21-287 Effectiveness of School-Based Health Centers to Advance Health Equity (R01 Clinical Trial Optional)
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Notice to Extend Expiration Date for PAR-20-277: Secondary Analysis and Integration of Existing Data to Elucidate the Genetic Architecture of Cancer Risk and Related Outcomes (R21 Clinical Trial Not Allowed)
Contact:
Topics: Gene Discovery, Genomics & Multi-Omics Analysis, Oral, Oropharyngeal & Salivary Gland Cancers |
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Notice of NIDCR Participation in PAR-19-343 "Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Clinical Trial Not Allowed)"
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RESCINDED - Notice of Intent to Publish a Funding Opportunity Announcement for Blueprint MedTech: Prototype Developer (U18 Clinical Trial Not Allowed)
Contact:
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)"
Contact:
Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Periodontal Diseases, Salivary Biology & Dysfunction, Sjogren’s Disease, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health |
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NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)"
Contact:
Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Periodontal Diseases, Salivary Biology & Dysfunction, Sjogren’s Disease, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health |
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Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional)
Contact:
Topics: Oral Health Disparities & Inequities, Small Business (SBIR/STTR), Technology Development |
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Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional)
Contact:
Topics: Oral Health Disparities & Inequities, Small Business (SBIR/STTR), Technology Development |
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Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional)
Contact:
Topics: Bioinformatics, Computational Biology & Data Science, Gene Discovery, Genomics & Multi-Omics Analysis |
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Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional)
Contact:
Topics: Bioinformatics, Computational Biology & Data Science, Gene Discovery, Genomics & Multi-Omics Analysis |
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Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed)
Contact:
Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Career Development, Clinical Research & Clinical Trials, Common Fund Programs, Conferences & Meetings, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, National Dental Practice-Based Research Network, Oral & Comprehensive Health, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Periodontal Diseases, Research Training & Fellowships, Salivary Biology & Dysfunction, Sjogren’s Disease, Small Business (SBIR/STTR), Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health |
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NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed)
Contact:
Topics: Career Development, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Research Training & Fellowships |
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Notice of Special Interest (NOSI): Lymphatic System in Health and Disease (R01)
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Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)
Contact:
Topics: Bioinformatics, Computational Biology & Data Science, Oral, Oropharyngeal & Salivary Gland Cancers |
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Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R21 Clinical Trials Not Allowed)
Contact:
Topics: Bioinformatics, Computational Biology & Data Science, Oral, Oropharyngeal & Salivary Gland Cancers |
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Notice of Special Interest (NOSI): Interventions to promote mental well-being in populations that experience health disparities through social, cultural, and environmental connectedness
Contact:
Topics: Behavioral & Social Science, Oral Health Disparities & Inequities |
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Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact:
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44 Clinical Trial Optional)
Contact:
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
Contact:
Topics: Clinical Research & Clinical Trials, Oral Health Disparities & Inequities |
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HEAL Initiative-Early-Stage Discovery of New Pain Targets Within the Understudied Druggable Proteome (R03 Clinical Trial Not Allowed)
Contact:
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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Center for Inherited Disease Research (CIDR) High Throughput Sequencing and Genotyping Resource Access (X01 Clinical Trial Not Allowed)
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INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Predoctoral to Postdoctoral Fellow Transition Award (F99/K00 Clinical Trial Not Allowed)
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Request for Information (RFI): Food is Medicine Research Opportunities
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Notice of Special Interest (NOSI): Supporting the Exploration of Cloud in NIH-supported Research
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Notice of Special Interest (NOSI): Research to Address Vaccine Uptake and Implementation among Populations Experiencing Health Disparities
Contact:
Topics: Behavioral & Social Science, COVID-19, Dissemination & Implementation Science, Oral Health Disparities & Inequities |
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Building Interdisciplinary Research Careers in Women's Health (BIRCWH) (K12 Clinical Trial Optional)
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NIDCR Small Research Grants for Analyses of Existing Genomics Data (R03 Clinical Trial Not Allowed)
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NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
Contact:
Topics: Clinical Research & Clinical Trials, Epidemiology |
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Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19)
Contact:
Topics: Clinical Research & Clinical Trials, COVID-19, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics |
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NIDCR Research Grants for Analyses of Existing Genomics Data (R01) (Clinical Trial Not Allowed)
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Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research
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Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional)
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Notice of Change in Funding Opportunity Purpose of NIDCR Small Research Grants for Analyses of Existing Genomics Data (PAR-23-132)
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Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)
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Notice of Special Interest (NOSI): Applications of Data Science in Translational Dental, Oral, and Craniofacial Research
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Notice of Special Interest (NOSI): Maternal Health and the Dental, Oral, and Craniofacial Development of their Children
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Omics Phenotypes Related to Down Syndrome for the INCLUDE Project (X01 Clinical Trial Not Allowed)
Contact:
Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Gene Discovery, Genomics & Multi-Omics Analysis |
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Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)
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Enhancement and Management of Established Biomedical Data Repositories and Knowledgebases (U24 Clinical Trial Not Allowed)
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Addressing the Impact of Structural Racism and Discrimination on Minority Health and Health Disparities (R01 - Clinical Trial Optional)
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Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases
Contact:
Topics: Epidemiology, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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In-Depth Phenotyping and Research Using IMPC-Generated Knockout Mouse Strains Exhibiting Embryonic or Perinatal Lethality or Subviability (R01 Clinical Trial Not Allowed)
Contact:
Topics: Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology |
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Small Research Grants for Analyses of Gabriella Miller Kids First Pediatric Research Data (R03 Clinical Trial Not Allowed)
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Extramural Loan Repayment Program for Clinical Researchers (LRP-CR)
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Extramural Loan Repayment Program for Research in Emerging Areas Critical to Human Health (LRP-REACH)
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Extramural Loan Repayment Program for Pediatric Research (LRP-PR)
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Extramural Clinical Research Loan Repayment Program for Individuals from Disadvantaged Backgrounds (LRP-IDB)
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Extramural Loan Repayment Program for Health Disparities Research (LRP-HDR)
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Extramural Loan Repayment Program for Contraception and Infertility Research (LRP-CIR)
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Interventions for Stigma Reduction to Improve HIV/AIDS Prevention, Treatment and Care in Low- and Middle- Income Countries (R01 - Clinical Trial Optional)
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HIV-associated Non-Communicable Diseases Research at Low- and Middle-Income Country Institutions (R21 Clinical Trial Optional)
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Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities
Contact:
Topics: Dissemination & Implementation Science, Oral Health Disparities & Inequities |
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Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes
Contact:
Topics: Behavioral & Social Science, Clinical Research & Clinical Trials, Dissemination & Implementation Science |
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Notice of Special Interest: Administrative Supplements to Promote Research Continuity and Retention of NIH Mentored Career Development (K) Award Recipients and Scholars
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Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards
Contact:
Topics: Behavioral & Social Science, Bioinformatics, Computational Biology & Data Science, Clinical Research & Clinical Trials, Common Fund Programs, COVID-19, Craniofacial & Dental Developmental Biology, Craniofacial Skeletal Biology & Pathobiology, Dental Caries, Dental Materials & Biomaterials, Dissemination & Implementation Science, Epidemiology, Fluoride & Fluorosis, Gene Discovery, Genomics & Multi-Omics Analysis, Global Health, HIV/AIDS & Oral Health, International Research Activities, Mineralized Tissues & Mineralization, Mucosal Diseases, Oral & Comprehensive Health, Oral Health Disparities & Inequities, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Oral Microbiota and Bacterial Disease, Oral Opportunistic Pathogens and Viral Disease, Oral, Oropharyngeal & Salivary Gland Cancers, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Parent Announcements & Trans-NIH Announcements, Periodontal Diseases, Salivary Biology & Dysfunction, Statistical Analysis & Data Science, Technology Development, Tissue Engineering & Regenerative Medicine, Women's Health |
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STrengthening Research Opportunities for NIH Grants (STRONG): Structured Institutional Needs Assessment and Action Plan Development for Resource Limited Institutions (RLIs) (UC2 - Clinical Trial Not Allowed)
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Notice of Special Interest: Achieving Tissue Robustness Through Harnessing Immune System Plasticity
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Notice of Special Interest (NOSI): Single-Cell Level Spatiotemporal Mapping of Dental and Craniofacial Embryogenesis
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
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Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed)
The purpose of this funding opportunity announcement is to encourage collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. Contact:Topics: Dental Materials & Biomaterials, Tissue Engineering & Regenerative Medicine |
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32)
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Notice of The Common Fund’s Participation in the Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Program
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31)
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Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to support studies that will identify, develop, and/or test strategies for overcoming barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, practices, programs, tools, treatments, guidelines, and policies. Studies that promote equitable dissemination and implementation of evidence-based interventions among underrepresented communities are encouraged. Conversely, there is a benefit in understanding circumstances that create a need to stop or reduce (de-implement) the use of practices that are ineffective, unproven, low-value, or harmful. In addition, studies to advance dissemination and implementation research methods and measures are encouraged. All applications must be within the scope of the mission of one of the Institutes/Centers listed above. Contact:Topics: Dissemination & Implementation Science |
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31-Diversity)
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INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Clinical Research Short Course (R25 Independent Clinical Trial Not Allowed)
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Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
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Notice of Special Interest (NOSI): The Functional Oral Microbiome
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Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed)
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NIDCR Notice of Participation in PAR-23-109, “NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)”
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NIH Medical Scientist Partnership Program (FM1 Clinical Trial Not Allowed)
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Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations
Contact:
Topics: Behavioral & Social Science, Oral Health Disparities & Inequities |
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Centers for AIDS Research (P30 Clinical Trial Not Allowed)
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Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
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Notice of Special Interest (NOSI): Administrative Supplements to NCATS CTSA Program KL2/K12 Institutional Career Development Awards as part of the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project
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Notice of Special Interest (NOSI): Promoting Mechanistic Research on Therapeutic and Other Biological Properties of Minor Cannabinoids and Terpenes
Contact:
Topics: Clinical Research & Clinical Trials, Oral Immunology, Immunopathology & Immunotherapy, Oral Microbiology & Metagenomics, Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery
Contact:
Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |
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HEAL Initiative: Translational Development of Diagnostic and Therapeutic Devices (R18 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) is to develop clinical-grade prototypes intended for use as safe, effective, and non-addictive device-based technologies and approaches to treat pain. The goal of the program is to demonstrate treatment using credible neural targets for device-based interventions and/or diagnostics for pain, building upon the latest mechanistic knowledge about the anatomy and physiology of central, spinal, and peripheral pathways involved in pain. Awarded activities will facilitate the translation of new devices up to the stage of readiness for first in human (FIH) clinical trials by overcoming key challenges identified during preliminary proof-of-concept studies. The scope of the program includes technology development and optimization, and studies to prepare for approvals for human use. Contact:Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology, Technology Development |
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HEAL Initiative: Interdisciplinary Team Science to Uncover the Mechanisms of Pain Relief by Medical Devices (RM1 Clinical Trial Optional)
More than 25 million Americans suffer from daily chronic pain, a highly debilitating medical condition that is complex and difficult to manage. In recent decades, there has been an overreliance in the prescription of opioids for chronic pain despite their poor ability to improve function and high addiction liability. This contributed to a significant and alarming epidemic of opioid overdose deaths and addictions. Innovative scientific solutions to develop alternative pain treatment options are thus critically needed. Through targeted research efforts, the NIH HEAL Initiative aims to support the development of safe and effective devices to treat pain with little or no addiction liability. This funding opportunity announcement (FOA) is designed to support interdisciplinary research teams of multiple PD/PIs to investigate the mechanism of action of pain relief by medical devices with the overall goal of optimizing therapeutic outcomes for FDA-approved or -cleared technologies. Program teams are expected to accomplish goals that require considerable synergy and collaborative interactions. Teams must leverage appropriate multi-disciplinary expertise to develop new principles and methods for experimentation, analysis, and interpretation. Teams are encouraged to consider objectives that will produce major advances in the field of pain relief by medical devices. Contact:Topics: Orofacial Pain, Temporomandibular Joint Disorder & Neurobiology |