Neuroscience of Orofacial Pain & Temporomandibular Disorders Program

The Neuroscience of Orofacial Pain and Temporomandibular Disorders Program supports basic, translational, and clinical research on:
  • Orofacial pain and neuropathies
  • Temporomandibular joint and muscle disorders
  • Development of biomarkers for diagnostics and prognostics
  • development of therapeutics.
In addition, the program encourages research that is responsive to trans-NIH initiatives including the NIH Pain Consortium, the NIH Neuroscience Blueprint, and the NIH Common Fund.

Staff Contacts

Funding Opportunity Announcements

Title Staff Contact Opportunity Number Activity Code Expiration Date
Optimization of Non-addictive Therapies [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Not Allowed) RFA-NS-19-010 D71, UG3, UH3
Limited Competition: Restoring Research Resources Lost or Damaged Due to Hurricanes Harvey, Irma, and Maria (R24 Clinical Trial Optional) RFA-OD-18-102 R24
Promoting Research on Music and Health: Fundamentals and Applications (R21 Clinical Trials Optional) RFA-NS-19-009 R21
Promoting Research on Music and Health: Fundamentals and Applications (R01 Clinical Trials Optional) RFA-NS-19-008 R01
Research on Chronic Overlapping Pain Conditions (R21 Clinical Trial Not Allowed) PA-18-939 R21
Research on Chronic Overlapping Pain Conditions (R01 Clinical Trial Optional) PA-18-937 R01
Research on Chronic Overlapping Pain Conditions (R21 Clinical Trial Not Allowed) PA-18-939 R21
Research on Chronic Overlapping Pain Conditions (R01 Clinical Trial Optional) PA-18-937 R01
NIH Administrative Supplements to Recover Losses Due to Hurricanes Harvey, Irma, and Maria Under the Bipartisan Budget Act of 2018 Non-Construction (Admin Supp Clinical Trial Optional) PA-18-936 D43, D71, DP1
Analytical and/or Clinical Validation of a Candidate Biomarker for Pain (R61/R33 Clinical Trial Optional) RFA-NS-18-046 R33, R61
Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R21 Clinical Trial Not Allowed) RFA-NS-18-042 D71, R21
Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R21 Clinical Trial Not Allowed) RFA-NS-18-042 D71, R21
NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35 Clinical Trial Not Allowed) RFA-DE-19-005 D71, R35
NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25) RFA-NS-19-007 R25
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-18-906 C06, D43, D71
Clinical Coordination Center for Common Fund Acute to Chronic Pain Signatures (A2CPS) Program (U24 Clinical Trial Optional) RFA-RM-18-035 U24
Multisite Clinical Center Common Fund Acute to Chronic Pain Signatures Program: Acute Peri-operative Pain (UM1 Clinical Trial Optional) RFA-RM-18-034 UM1
Multisite Clinical Center Common Fund Acute to Chronic Pain Signatures Program: Acute Pain from Musculoskeletal Trauma (UM1 Clinical Trial Optional) RFA-RM-18-033 UM1
Omics Data Generation Centers (ODGCs) for Common Fund Acute to Chronic Pain Signatures Program (U54 Clinical Trial Optional) RFA-RM-18-032 U54
Innovative Adaptations to Simplify Existing Technologies for Manipulation and Analysis of Glycans (U01 Clinical Trial Not Allowed) RFA-RM-18-037 U01
Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01 Clinical Trial Not Allowed) RFA-RM-18-036 U01
Advancing Extracellular RNA (exRNA) Communication Research: Towards Single Extracellular Vesicle (EV) Sorting, Isolation, and Analysis of Cargo (UG3/UH3 Clinical Trial Not Allowed) RFA-RM-18-028 UG3, UH3
Advancing Extracellular RNA (exRNA) Communication Research: Improved Isolation and Analysis of exRNA-Carrier Subclasses (UG3/UH3 Clinical Trial Not Allowed) RFA-RM-18-027 UG3, UH3
Limited Competition: Data Management and Resource Repository (DMRR) on Extracellular RNA (U54 Clinical Trial Not Allowed) RFA-RM-18-026 D71, U54
Discovery of Biomarkers, Biomarker Signatures, and Endpoints for Pain (R61/R33 Clinical Trial Optional) RFA-NS-18-041 R33, R61
Innovative Technologies to Non-Invasively Monitor Genome Edited Cells In Vivo (UH2/UH3 Clinical Trial Not Allowed) RFA-RM-18-025 D71, UG3, UH3
Expanding the Human Genome Engineering Repertoire (U01 Clinical Trial Not Allowed) RFA-RM-18-024 D71, U01
Innovative Technologies to Deliver Genome Editing Machinery to Disease-relevant Cells and Tissues (UG3/UH3 Clinical Trial Not Allowed) RFA-RM-18-023 UG3, UH3
Development of Cell and Tissue Platforms to Detect Adverse Biological Consequences of Somatic Cell Genome Editing (U01 Clinical Trial Not Allowed) RFA-RM-18-022 D71, U01
Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional) PAR-18-836 R21
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-18-837 R41, R42, R43
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-18-591 C06, D43, D71
Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-18-591 C06, D43, D71
Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) PA-18-658 DP1, DP2, DP4
PHS 2018-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) PA-18-576 R41, R42
PHS 2018-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) PA-18-575 R41, R42
PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-18-574 R43, R44
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) PA-18-648 R13
Global Brain and Nervous System Disorders Research Across the Lifespan (R21) PAR-17-313 R21
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3) - Clinical Trial Optional PAR-18-546 UG3, UH3
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44) - Clinical Trial Optional PAR-18-541 U44
Administrative Supplements for Research on Dietary Supplements (Admin Supp) PA-17-307 P30, P40, P50
Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed) PA-18-504 R15
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-18-489 R21
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-18-484 R01
Mechanisms, Models, Measurement, and Management in Pain Research (R21 Clinical Trial Optional) PA-18-159 R21
Mechanisms, Models, Measurement, and Management in Pain Research (R01 Clinical Trial Optional) PA-18-141 R01
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44) PA-17-147 R43, R44
Factors Underlying Differences in Female and Male Presentation for Dental, Oral, and Craniofacial Diseases and Conditions (R01) PA-16-295 R01
Factors Underlying Differences in Female and Male Presentation for Dental, Oral, and Craniofacial Diseases and Conditions (R21) PA-16-296 R21
Tools for Cell Line Identification (R43/R44) PA-16-186 R43, R44
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42) PA-17-148 R41, R42
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) PAR-15-344 R03
Change of Grantee Organization (Type 7 Parent) PA-16-285 C06, D43, D71
Successor-in-Interest (Type 6 Parent) PA-16-286 C06, D43, D71
Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp) PA-16-289 DP1, DP2, DP3
NIDCR Small Grant Program for New Investigators (R03) PAR-16-409 R03
SBIR Technology Transfer (R43/R44) PA-15-354 R43, R44
Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44) PA-16-180 R43, R44
Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R41/R42) PA-16-181 R41, R42