Grant Programs | National Institute of Dental and Craniofacial Research

The Neuroscience of Orofacial Pain and Temporomandibular Disorders Program supports basic, translational, and clinical research on:

Orofacial pain and neuropathies
Temporomandibular joint and muscle disorders
Development of biomarkers for diagnostics and prognostics
development of therapeutics.

In addition, the program encourages research that is responsive to trans-NIH initiatives including the NIH Pain Consortium, the NIH Neuroscience Blueprint, and the NIH Common Fund.

More About This Program

Staff Contacts

All Staff Contacts

Yolanda Vallejo, PhD

Director, Neuroscience of Orofacial Pain and Temporomandibular Disorders Program

(301) 827-4655

Yolanda.Vallejo@nih.gov

Funding Opportunity Announcements

View All

Title	Staff Contact	Opportunity Number	Activity Code	Expiration Date
Achieving Tissue Robustness Through Harnessing Immune System Plasticity (R21 Clinical Trial Not Allowed)	Jason Wan, PhD (301) 594-9898 jasonwan@mail.nih.gov Gallya Gannot, DMD, PhD (301) 451-5096 gannotg@mail.nih.gov Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov Chiayeng Wang, PhD (301) 827-4647 chiayeng.wang@nih.gov Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov Nadya Lumelsky, PhD (301) 594-7703 nadyal@nidcr.nih.gov	PAR-19-173	R21	05/08/2022
Achieving Tissue Robustness Through Harnessing Immune System Plasticity (R01 Clinical Trial Not Allowed)	Jason Wan, PhD (301) 594-9898 jasonwan@mail.nih.gov Gallya Gannot, DMD, PhD (301) 451-5096 gannotg@mail.nih.gov Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov Chiayeng Wang, PhD (301) 827-4647 chiayeng.wang@nih.gov Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov Nadya Lumelsky, PhD (301) 594-7703 nadyal@nidcr.nih.gov	PAR-19-172	R01	03/08/2022
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed)	Multiple Contacts	PAR-19-134	R15	01/08/2022
NIH Research Evaluation and Commercialization Hub (REACH) Awards (U01 Clinical Trial Not Allowed)	Multiple Contacts	RFA-OD-19-014	U01	03/20/2019
Limited Competition: NeuroImaging Tools & Resources Collaboratory (R24 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-EB-18-004	U24	02/23/2019
HEAL Initiative: Pain Management Effectiveness Research Network: Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)	Dena Fischer, DDS, MSD, MS (301) 594-4876 dena.fischer@nih.gov	RFA-NS-19-020	UG3, UH3	03/07/2019
HEAL Initiative: Tissue Chips to Model Nociception, Addiction, and Overdose (UG3/UH3 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-TR-19-003	UG3, UH3	03/01/2019
HEAL Initiative: Optimization of Non-addictive Therapies [Small Molecules and Biologics] to Treat Pain - (U44 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-020	U44	03/07/2019
HEAL Initiative: Clinical Devices to Treat Pain (UH3 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-018	UH3	02/23/2021
HEAL Initiative: Translational Devices to Treat Pain (U44 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-017	U44	02/23/2021
HEAL Initiative: Translational Devices to Treat Pain (UG3/UH3 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-016	UH3	02/23/2021
HEAL Initiative: Translational Development of Devices to Treat Pain (U18 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-EB-18-003	U18	02/23/2021
NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required)	Melissa Riddle, PhD (301) 451-3888 riddleme@nidcr.nih.gov Dena Fischer, DDS, MSD, MS (301) 594-4876 dena.fischer@nih.gov Nadya Lumelsky, PhD (301) 594-7703 nadyal@nidcr.nih.gov Kathryn Stein, PhD (301) 827-4653 kathryn.stein@nih.gov	PA-19-092	R21	01/08/2022
NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)	Melissa Riddle, PhD (301) 451-3888 riddleme@nidcr.nih.gov Dena Fischer, DDS, MSD, MS (301) 594-4876 dena.fischer@nih.gov Nadya Lumelsky, PhD (301) 594-7703 nadyal@nidcr.nih.gov Kathryn Stein, PhD (301) 827-4653 kathryn.stein@nih.gov	PA-19-091	R01	01/08/2022
Optimization of Non-addictive Therapies [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-010	D71, UG3, UH3	03/07/2019
Limited Competition: Restoring Research Resources Lost or Damaged Due to Hurricanes Harvey, Irma, and Maria (R24 Clinical Trial Optional)	Multiple Contacts	RFA-OD-18-102	R24	12/15/2018
Promoting Research on Music and Health: Fundamentals and Applications (R21 Clinical Trials Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-009	R21	03/01/2019
Promoting Research on Music and Health: Fundamentals and Applications (R01 Clinical Trials Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-19-008	R01	03/01/2019
Research on Chronic Overlapping Pain Conditions (R21 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-18-939	R21	01/08/2022
Research on Chronic Overlapping Pain Conditions (R01 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-18-937	R01	01/08/2022
Research on Chronic Overlapping Pain Conditions (R21 Clinical Trial Not Allowed)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-18-939	R21	01/08/2022
Research on Chronic Overlapping Pain Conditions (R01 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-18-937	R01	01/08/2022
NIH Administrative Supplements to Recover Losses Due to Hurricanes Harvey, Irma, and Maria Under the Bipartisan Budget Act of 2018 Non-Construction (Admin Supp Clinical Trial Optional)	Multiple Contacts	PA-18-936	D43, D71, DP1	01/08/2022
Analytical and/or Clinical Validation of a Candidate Biomarker for Pain (R61/R33 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-18-046	R33, R61	03/13/2020
Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R21 Clinical Trial Not Allowed)		RFA-NS-18-042	D71, R21	11/13/2018
Discovery and Validation of Novel Targets for Safe and Effective Pain Treatment (R21 Clinical Trial Not Allowed)		RFA-NS-18-042	D71, R21	11/13/2018
NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35 Clinical Trial Not Allowed)	Lillian Shum, PhD (301) 594-0618 lillian.shum@nih.gov	RFA-DE-19-005	D71, R35	12/06/2018
NIH Blueprint Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (R25)	Lynn King, PhD (301) 594-5006 lynn.king@nih.gov	RFA-NS-19-007	R25	02/16/2019
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed)	Lynn King, PhD (301) 594-5006 lynn.king@nih.gov	PA-18-906	C06, D43, D71	09/08/2021
Clinical Coordination Center for Common Fund Acute to Chronic Pain Signatures (A2CPS) Program (U24 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-RM-18-035	U24	10/25/2018
Multisite Clinical Center Common Fund Acute to Chronic Pain Signatures Program: Acute Peri-operative Pain (UM1 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-RM-18-034	UM1	10/25/2018
Multisite Clinical Center Common Fund Acute to Chronic Pain Signatures Program: Acute Pain from Musculoskeletal Trauma (UM1 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-RM-18-033	UM1	10/25/2018
Omics Data Generation Centers (ODGCs) for Common Fund Acute to Chronic Pain Signatures Program (U54 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-RM-18-032	U54	10/24/2018
Innovative Adaptations to Simplify Existing Technologies for Manipulation and Analysis of Glycans (U01 Clinical Trial Not Allowed)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov	RFA-RM-18-037	U01	10/30/2018
Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01 Clinical Trial Not Allowed)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov	RFA-RM-18-036	U01	10/30/2018
Advancing Extracellular RNA (exRNA) Communication Research: Towards Single Extracellular Vesicle (EV) Sorting, Isolation, and Analysis of Cargo (UG3/UH3 Clinical Trial Not Allowed)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov	RFA-RM-18-028	UG3, UH3	10/24/2018
Advancing Extracellular RNA (exRNA) Communication Research: Improved Isolation and Analysis of exRNA-Carrier Subclasses (UG3/UH3 Clinical Trial Not Allowed)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov	RFA-RM-18-027	UG3, UH3	10/24/2018
Limited Competition: Data Management and Resource Repository (DMRR) on Extracellular RNA (U54 Clinical Trial Not Allowed)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov	RFA-RM-18-026	D71, U54	10/24/2018
Discovery of Biomarkers, Biomarker Signatures, and Endpoints for Pain (R61/R33 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	RFA-NS-18-041	R33, R61	03/18/2020
Innovative Technologies to Non-Invasively Monitor Genome Edited Cells In Vivo (UH2/UH3 Clinical Trial Not Allowed)	Lu Wang, PhD (301) 594-4846 wanglu@mail.nih.gov	RFA-RM-18-025	D71, UG3, UH3	10/19/2018
Expanding the Human Genome Engineering Repertoire (U01 Clinical Trial Not Allowed)	Lu Wang, PhD (301) 594-4846 wanglu@mail.nih.gov	RFA-RM-18-024	D71, U01	10/19/2018
Innovative Technologies to Deliver Genome Editing Machinery to Disease-relevant Cells and Tissues (UG3/UH3 Clinical Trial Not Allowed)	Lu Wang, PhD (301) 594-4846 wanglu@mail.nih.gov	RFA-RM-18-023	UG3, UH3	10/19/2018
Development of Cell and Tissue Platforms to Detect Adverse Biological Consequences of Somatic Cell Genome Editing (U01 Clinical Trial Not Allowed)	Lu Wang, PhD (301) 594-4846 wanglu@mail.nih.gov	RFA-RM-18-022	D71, U01	10/19/2018
Global Brain and Nervous System Disorders Research Across the Lifespan (R21 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PAR-18-836	R21	11/08/2019
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed)	Lynn King, PhD (301) 594-5006 lynn.king@nih.gov Multiple Contacts	PA-18-837	R41, R42, R43	09/05/2021
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)	Multiple Contacts	PA-18-591	C06, D43, D71	01/26/2021
Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)	Multiple Contacts	PA-18-591	C06, D43, D71	01/26/2021
Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional)	Multiple Contacts	PA-19-165	DP1, DP2, DP4	02/21/2019
PHS 2018-02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)	R. Dwayne Lunsford, PhD (301) 827-4635 lunsfordr@nidcr.nih.gov	PA-18-575	R41, R42	04/16/2019
PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)	R. Dwayne Lunsford, PhD (301) 827-4635 lunsfordr@nidcr.nih.gov	PA-18-574	R43, R44	04/06/2019
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed)	Alicia Dombroski, PhD (301) 594-4805 alicia.dombroski@nih.gov	PA-18-648	R13	01/08/2021
Global Brain and Nervous System Disorders Research Across the Lifespan (R21)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PAR-17-313	R21	11/08/2019
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3) - Clinical Trial Optional	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PAR-18-546	UG3, UH3	05/08/2020
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development for Disorders of the Nervous System (U44) - Clinical Trial Optional	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PAR-18-541	U44	05/08/2020
Administrative Supplements for Research on Dietary Supplements (Admin Supp)	Multiple Contacts	PA-18-817	P30, P40, P50	04/16/2020
Academic Research Enhancement Award (Parent R15 Clinical Trial Not Allowed)	Multiple Contacts	PA-18-504	R15	01/08/2021
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed)	Multiple Contacts	PA-18-484	R01	01/08/2021
Mechanisms, Models, Measurement, and Management in Pain Research (R21 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-18-159	R21	05/08/2019
Mechanisms, Models, Measurement, and Management in Pain Research (R01 Clinical Trial Optional)	Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-18-141	R01	05/08/2019
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03)	Multiple Contacts	PAR-15-344	R03	09/08/2018
Change of Grantee Organization (Type 7 Parent)	Multiple Contacts	PA-18-590	C06, D43, D71	01/26/2021
Successor-in-Interest (Type 6 Parent)	Multiple Contacts	PA-16-286	C06, D43, D71	05/26/2019
SBIR Technology Transfer (R43/R44)	R. Dwayne Lunsford, PhD (301) 827-4635 lunsfordr@nidcr.nih.gov	PA-15-354	R43, R44	09/06/2018
Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R43/R44)	R. Dwayne Lunsford, PhD (301) 827-4635 lunsfordr@nidcr.nih.gov	PA-16-180	R43, R44	04/06/2019
Development and Commercialization of Technologies to Create, Characterize or Improve Animal Models of Human Disease (R41/R42)	R. Dwayne Lunsford, PhD (301) 827-4635 lunsfordr@nidcr.nih.gov	PA-16-181	R41, R42	04/06/2019
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44)	Lillian Shum, PhD (301) 594-0618 lillian.shum@nih.gov	PA-17-147	R43, R44	01/06/2020
Factors Underlying Differences in Female and Male Presentation for Dental, Oral, and Craniofacial Diseases and Conditions (R01)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov Chiayeng Wang, PhD (301) 827-4647 chiayeng.wang@nih.gov Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-16-295	R01	09/08/2019
Factors Underlying Differences in Female and Male Presentation for Dental, Oral, and Craniofacial Diseases and Conditions (R21)	Preethi Chander, PhD (301) 827-4620 preethi.chander@nih.gov Chiayeng Wang, PhD (301) 827-4647 chiayeng.wang@nih.gov Yolanda Vallejo, PhD (301) 827-4655 Yolanda.Vallejo@nih.gov	PA-16-296	R21	09/08/2019
Tools for Cell Line Identification (R43/R44)	R. Dwayne Lunsford, PhD (301) 827-4635 lunsfordr@nidcr.nih.gov	PA-16-186	R43, R44	04/06/2019
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42)	Lillian Shum, PhD (301) 594-0618 lillian.shum@nih.gov	PA-17-148	R41, R42	01/06/2020

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Neuroscience of Orofacial Pain & Temporomandibular Disorders Program

Staff Contacts

Funding Opportunity Announcements

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Previously Funded Grants

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Neuroscience of Orofacial Pain & Temporomandibular Disorders Program

Staff Contacts

Funding Opportunity Announcements

Grantee News

NIDCR News

Previously Funded Grants