Small Business Innovation Research/Small Business Technology Transfer Research (SBIR/STTR) Program

The SBIR and STTR programs are congressionally mandated set-aside programs for domestic small business concerns to engage in Research/Research and Development (R/R&D) that has the potential for commercialization.
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Staff Contacts

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Funding Opportunities & Notices

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Title Staff Contact Opportunity number Activity Code Expiration Date
Notice of Special Interest: Alzheimers-Focused Administrative Supplements for NIH Grants that are Not Focused on Alzheimers Disease NOT-AG-22-025 333
Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track - R44 - Clinical Trial Not Allowed) RFA-DE-23-008 R44
Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (R42 Fast-Track - Clinical Trial Not Allowed) RFA-DE-23-007 R42
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) PA-20-025 R41/R42
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) PA-20-047 R43/R44
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-20-060 U01
Notice of Special Interest (NOSI): Administrative Supplements for Research on Sex and/or Gender Influences (Admin Supp Clinical Trial Optional) NOT-OD-22-030 333
Notice of Special Interest (NOSI): Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional) NOT-OD-22-031 333
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-20-055 333
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional) PA-20-135  C06, L40, P2C
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance (SB1, Clinical Trial Not Allowed) PAR-20-128 SB1
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed) PAR-20-129 SB1
PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-22-176 R43/R44
PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) PA-22-178 R41/R42
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-20-275 666
Notice of Special Interest (NOSI): Administrative Supplement for Providing Technical and Business Assistance (TABA) Funding to SBIR/STTR Awardees (Admin Supp) NOT-OD-21-062 333
Technical and Business Assistance (TABA) Needs Assessment Program for National Institutes of Health (NIH) Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Awardees NOT-OD-21-023 R41, R42, R43
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-20-272 333
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) PA-21-151 R13
Notice of Special Interest (NOSI): Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp Clinical Trial Optional) NOT-OD-22-032 333
Innovation Corps (I-Corps) at NIH Program for NIH and CDC Translational Research (Admin Supp Clinical Trial NOT Allowed) PAR-22-073 333
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-21-268 777
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 333
Notice of Special Interest (NOSI): Administrative Supplements for Research on Womens Health in the IDeA States NOT-GM-22-005 333
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice of Intent to Publish a Funding Opportunity Announcement for Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track - R44 Clinical Trial Not Allowed) NOT-DE-22-011
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
Notice of Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in RFA-MD-22-004 Innovations for Healthy LivingImproving Minority Health and Eliminating Health Disparities (R43/R44- Clinical Trial Optional) NOT-DE-22-004 R43/R44
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Special Interest: SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed) NOT-NS-22-017 R43/R44
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R43/R44, R41/R42

Previously Funded Grants

NIH RePORTER - Research Portfolio Online Reporting Tool (RePORT)