Small Business Innovation Research/Small Business Technology Transfer Research (SBIR/STTR) Program

The SBIR and STTR programs are congressionally mandated set-aside programs for domestic small business concerns to engage in Research/Research and Development (R/R&D) that has the potential for commercialization.

Funding Opportunities & Notices

Title Staff Contact Opportunity number Activity Code Expiration Date
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-21-345 333
Notice of Special Interest (NOSI): Administrative Supplements for Research on Womens Health in the IDeA States NOT-GM-22-005 333
Notice of Special Interest: SBIR Technology Transfer (R43/R44 Clinical Trial Not Allowed) NOT-NS-22-017 R43/R44
Notice of NIDCR Participation in RFA-NS-23-006, "HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed)" NOT-DE-24-004
HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed) RFA-NS-23-007 R41/R42
Notice of NIDCR Participation in RFA-NS-23-007, "HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)" NOT-DE-24-005
HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 Clinical Trial Not Allowed) RFA-NS-23-006 R43/R44
PHS 2024-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-24-245 R43/R44
PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) PA-24-247 R41/R42
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 S10
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R43/R44, R41/R42
Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed) PAR-24-038 RC2
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-23-189 R16, R21/R33, R41/R42
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) NOT-OD-23-170 332, 333, 666
Innovations for Healthy Living - Improving Minority Health and Eliminating Health Disparities (R43/R44 - Clinical Trial Optional) RFA-MD-24-006 R43, R44
Technologies for Improving Minority Health and Eliminating Health Disparities (R41/R42- Clinical Trial Optional) RFA-MD-24-007 R41, R42
Notice of Special Interest: R13 Support for Conferences and Scientific Meetings to Support Consensus Building for Autoimmune Disease Research Related Common Data Elements NOT-OD-24-145 R13
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Participation of the National Institute of Dental and Craniofacial Research (NIDCR) in RFA-MD-22-004 Innovations for Healthy LivingImproving Minority Health and Eliminating Health Disparities (R43/R44- Clinical Trial Optional) NOT-DE-22-004 R43/R44
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice of Changes to NIDCR's Clinical Terms of Award (CToA) Policy NOT-DE-19-008
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
Notice of Intent to Publish a Funding Opportunity Announcement for Data-Driven Tools to Accelerate the Clinical Translation of Novel Dental, Oral, and Craniofacial Biomaterials (Fast-Track - R44 Clinical Trial Not Allowed) NOT-DE-22-011
Notice of Change in Funding Opportunity Expiration Date and Eligible Organizations for "Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)" (PAR-24-038) NOT-DE-24-007 RC2
Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed) PAR-24-131 R43/R44
Notice of Special Interest (NOSI): Translating Biomaterials-Based Technologies to Commercially Viable Products NOT-EB-24-001 R41/R42, R43/R44
Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed) PAR-24-133 R41/R42
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-24-254
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-24-253 332, 333, 666
Notice of Special Interest: Womens Health Research NOT-OD-24-079 R15, R01, K01