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NIDCR News 2014

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Announcement

To expose future dentists to careers in research, NIDCR offers an outstanding summer training opportunity in its intramural research labs for dental students.

Lillian Shum
Announcement

After a national search, Lillian R. Shum, PhD, has been selected to be the director of NIDCR’s Division of Extramural Research (DER).  She will provide leadership and guidance for the planning, development, implementation, and evaluation of NIDCR’s investment in biomedical and behavioral sciences. 

Kaposi's sarcoma cells (Source: National Cancer Institute)
Research Brief
Infection with a virus known as KSHV (also called Kaposi’s sarcoma herpesvirus, human herpesvirus-8, or HHV8) can cause Kaposi’s sarcoma, a cancer characterized by red or brownish purple growths in the mouth, on the skin, or elsewhere.
Human T-Cells
Research Brief
Without regulatory T cells (Treg cells), you’d likely die from out-of-control inflammation. Treg cells prevent your immune system from attacking your own tissues.
Biglycan helps to form blood vessels in broken bones that are healing. Black arrows point to blood vessels.
Research Brief
Thirty years ago, biglycan was thought to be merely a structural component that imparted mechanical stability to teeth, bones, muscles, cartilage, and tendons. Today, biglycan’s function is known to be far more complex, and scientists continue to publish papers about its many roles in the musculoskeletal system and beyond.
Formation of tooth-like structures in the dentin matrix.
Research Brief
In 1889, the American toymaker Charles Martin Crandall patented a then-novel board game called Pigs in Clover. It consisted of a large, circular labyrinth that players held in their hands and carefully tilted in one direction then another as a means to roll a colored marble from the clovered periphery, through a gated maze, and into the pigpen in the middle.
Fluorescent collagen internalized into the skin cells of a mouse
Research Brief
Better treatment options are needed for people diagnosed with head and neck cancers because the current therapies of surgery, radiation therapy, and chemotherapy control cancer at the cost of normal tissues, sometimes damaging them permanently.
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