Clinical Trials & Practice-Based Research Program

The Clinical and Practice-Based Research Program supports cross-sectional descriptive, case-control, prospective cohort and retrospective studies of dental, oral, and craniofacial diseases and disorders. The NIDCR-supported National Dental Practice-Based Research Network is a program in which national oral health studies are conducted in dental practices on topics of importance to practitioners and their patients.
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Staff Contacts

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NIDCR News

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Grantee News

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Funding Opportunities & Notices

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Title Staff Contact Opportunity number Activity Code Expiration Date
NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional) RFA-RM-22-019 DP2
National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed) PAR-20-073 X01
NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional) RFA-RM-22-020 R01
NIH Director’s Early Independence Awards (DP5 Clinical Trial Optional) RFA-RM-22-021 DP5
Clinical Research to Improve the Oral Health of Older Adults (R01 Clinical Trial Not Allowed) PAR-19-239 R01
Clinical Research to Improve the Oral Health of Older Adults (R21 Clinical Trial Not Allowed) PAR-19-240 R21
NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional) RFA-RM-22-018 U24
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) PA-20-025 R41/R42
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) PA-20-047 R43/R44
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-20-060 U01
Notice of Special Interest (NOSI): Administrative Supplements for Research on Sex and/or Gender Influences (Admin Supp Clinical Trial Optional) NOT-OD-22-030 333
Notice of Special Interest (NOSI): Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional) NOT-OD-22-031 333
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-20-055 333
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional) PA-20-135  C06, L40, P2C
Administrative Supplement for Research on Dietary Supplements (Admin Supp-Clinical Trial Not Allowed) PA-20-227 333
Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) PA-20-184  R01
NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required) PA-20-196 R21
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 R01
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-21-001 R01, R21
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-20-195 R21
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-20-275 666
National Dental Practice-Based Research Network Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Optional) PAR-20-306 UG3, UH3
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-20-272 333
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) PAR-21-038 R01
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required) PAR-21-039 R01
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed) PAR-21-084 R03
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) PA-21-151 R13
Notice of Special Interest (NOSI): Administrative Supplements for Research on Sexual and Gender Minority (SGM) Populations (Admin Supp Clinical Trial Optional) NOT-OD-22-032 333
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) PAR-21-343 U01
Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-21-155 R15
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-21-268 777
Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) RFA-OD-22-009 R01
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) PAR-22-167 UG3/UH3
Notice of Special Interest (NOSI): Administrative Supplements for Research on Womens Health in the IDeA States NOT-GM-22-005 333
Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) NOT-DE-18-015
Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) NOT-DE-21-017
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice to Extend the Expiration Date for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-20-037
Notice of Corrected Application Forms for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-18-016
Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA NOT-DE-21-020
Notice of Additional Receipt Dates for PAR-20-073 National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed) NOT-DE-20-024
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) NOT-DE-22-008
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-22-090 R21
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-22-160 R03
Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan NOT-OD-22-106 R03, R01, R34
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-107 333, R01, R34
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R43/R44, R41/R42

Previously Funded Grants

NIH RePORTER - Research Portfolio Online Reporting Tool (RePORT)