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Clinical Trials & Practice-Based Research Program

The Clinical and Practice-Based Research Program supports cross-sectional descriptive, case-control, prospective cohort and retrospective studies of dental, oral, and craniofacial diseases and disorders. The NIDCR-supported National Dental Practice-Based Research Network is a program in which national oral health studies are conducted in dental practices on topics of importance to practitioners and their patients.
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Funding Opportunities & Notices

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Title Staff Contact Opportunity number Activity Code Expiration Date
NIDCR Award for Sustaining Outstanding Achievement in Research (SOAR) (R35 Clinical Trial Not Allowed) RFA-DE-22-001 R35
NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional) RFA-RM-21-016 DP2
NIH Director’s New Innovator Award Program (DP2 Clinical Trial Optional) RFA-RM-21-016 DP2
NIH Directors Transformative Research Awards (R01 Clinical Trial Optional) RFA-RM-21-017 R01
NIH Director’s Transformative Research Awards (R01 Clinical Trial Optional) RFA-RM-21-017 R01
NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional) RFA-RM-21-015 DP1
NIH Director’s Pioneer Award Program (DP1 Clinical Trial Optional) RFA-RM-21-015 DP1
Notice of Special Interest: Alzheimers-Focused Administrative Supplements for NIH Grants that are Not Focused on Alzheimers Disease NOT-AG-21-018 333
Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trial Required) RFA-OD-20-003 R61/R33
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) PAR-19-134 R15
NIH Administrative Supplements to Recover Losses Due to Hurricanes Harvey, Irma, and Maria Under the Bipartisan Budget Act of 2018 Non-Construction (Admin Supp Clinical Trial Optional) PA-18-936 P2C, P01, OT3
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-19-145 R03
Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) PA-18-935 K99, R15, R01
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) PAR-19-276 R03
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) PAR-19-274 R01
National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed) PAR-20-073 X01
Clinical Research to Improve the Oral Health of Older Adults (R01 Clinical Trial Not Allowed) PAR-19-239 R01
Clinical Research to Improve the Oral Health of Older Adults (R21 Clinical Trial Not Allowed) PAR-19-240 R21
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) PA-20-047 R43/R44
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) PA-20-025 R41/R42
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-20-060 U01
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-20-055 333
Emergency Competitive Revision to Existing NIH Awards (Emergency Supplement - Clinical Trial Optional) PA-20-135  C06, L40, P2C
Administrative Supplement for Research on Dietary Supplements (Admin Supp-Clinical Trial Not Allowed) PA-20-227 333
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-21-001 R01, R21
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-20-195 R21
Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) PA-20-184  R01
NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required) PA-20-196 R21
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 R01
Successor-in-Interest (Type 6 Parent Clinical Trial Optional) PA-20-275 666
National Dental Practice-Based Research Network Clinical Trial or Observational Study Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Optional) PAR-20-306 UG3, UH3
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-20-272 333
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed) PAR-21-038 R01
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Humans Required) PAR-21-039 R01
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) NOT-DE-18-015
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice to Extend the Expiration Date for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-20-037
Notice of Corrected Application Forms for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-18-016
Notice of Additional Receipt Dates for PAR-20-073 National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed) NOT-DE-20-024
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed) PAR-21-084 R03
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) PA-21-151 R13
Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-21-155 R15

Previously Funded Grants

NIH RePORTER - Research Portfolio Online Reporting Tool (RePORT)