Clinical & Practice-Based Research Program

The Clinical and Practice-Based Research Program supports cross-sectional descriptive, case-control, prospective cohort and retrospective studies of dental, oral, and craniofacial diseases and disorders. The NIDCR-supported National Dental Practice-Based Research Network is a program in which national oral health studies are conducted in dental practices on topics of importance to practitioners and their patients.

Funding Opportunities & Notices

Title Staff Contact Opportunity number Activity Code Expiration Date
Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional) NOT-OD-24-031 332, 333, 666
PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-23-230 R43/R44
PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) PA-23-232 R41/R42
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed) PAR-23-219 SB1
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) PAR-21-343 U01
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-20-195 R21
Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-21-155 R15
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 R01
Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) PA-20-184 R01
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-21-268 777
Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) RFA-OD-22-009 R01
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) PAR-22-167 UG3/UH3
Notice of Special Interest (NOSI): Administrative Supplements for Research on Womens Health in the IDeA States NOT-GM-22-005 333
The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) RFA-OD-22-028 R01
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-22-090 R21
Notice of Special Interest (NOSI): Developing Academic Research Enhancement Award (AREA) and Research Enhancement Award Program (REAP) for Institutions with an emphasis on Down syndrome research (R15 Clinical Trial Not Allowed) NOT-OD-22-136 R15
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-123 R01
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-22-160 R03
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 S10
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R43/R44, R41/R42
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-23-032 333
Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed) PAR-24-038 RC2
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-23-004
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-23-162 U01
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-23-122 R01
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-23-189 R16, R21/R33, R41/R42
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) NOT-OD-23-170 332, 333, 666
NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)" NOT-DE-24-009 R01
NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)" NOT-DE-24-010 R01
Notice of Intent to Publish a Funding Opportunity Announcement for Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED) (U01 Clinical Trial Not Allowed) NOT-DE-22-013
Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) NOT-DE-18-015
Notice of Change Regarding Institutional Eligibility for PAR-19-134 and PAR-19-135 "Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools" NOT-DE-20-019
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials NOT-DE-21-014
Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) NOT-DE-22-008
Notice of Technical Assistance Webinar for RFA-DE-23-012 Practice-Based Research Integrating Multidisciplinary Experiences in Dental Schools (PRIMED) NOT-DE-22-017
Notice of Corrected Application Forms for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-18-016
Notice of National Institute of Dental and Craniofacial Research (NIDCR) Participation in PA-18-935 Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) NOT-DE-20-020
Notice to Extend the Expiration Date for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-20-037
Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) NOT-DE-21-017
Notice of Changes to NIDCR's Clinical Terms of Award (CToA) Policy NOT-DE-19-008
Notice of Additional Receipt Dates for PAR-20-073 National Dental Practice-Based Research Network Infrastructure Access (X01 Clinical Trial Not Allowed) NOT-DE-20-024
Notice of Change in Funding Opportunity Expiration Date and Eligible Organizations for "Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)" (PAR-24-038) NOT-DE-24-007 RC2
Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA NOT-DE-21-020