Clinical Research & Epidemiology Program

The Clinical Research & Epidemiology Program supports cross-sectional descriptive, case-control, prospective cohort and retrospective studies of dental, oral, and craniofacial diseases and disorders. Epidemiologic studies aimed at enhancing knowledge in the incidence, distribution, determinants and possible control of diseases and other factors relating to dental, oral, and craniofacial disease are also supported.

Funding Opportunities & Notices

Title Staff Contact Opportunity number Activity Code Expiration Date
Notice of Special Interest (NOSI): Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues (Admin Supp Clinical Trial Optional) NOT-OD-24-031 332, 333, 666
PHS 2023-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed) PA-23-230 R43/R44
PHS 2023-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed) PA-23-232 R41/R42
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed) PAR-23-219 SB1
Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) PA-20-184 R01
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-20-195 R21
Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 Clinical Trial Not Allowed) PAR-21-155 R15
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 R01
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects NOT-OD-21-137 333, R34, R01
Notice of Special Interest (NOSI): Electronic Nicotine Delivery Systems (ENDS) and Alternative Nicotine and Tobacco Delivery Systems: Population, Clinical and Applied Prevention Mechanisms of Health Effects NOT-OD-22-023 R21, R01, 333
Change of Recipient Organization (Type 7 Parent Clinical Trial Optional) PA-21-268 777
Transformative Research Award for the INCLUDE (Investigation of Co-occurring Conditions across the Lifespan to Understand Down syndrome) Project (R01 Clinical Trial Not Allowed) RFA-OD-22-009 R01
INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Exploratory/Developmental Research Grant Award (R21 Clinical Trial Not Allowed) RFA-OD-21-007 R21
Limited Competition: Clinical and Translational Science Award (CTSA) Program: Collaborative and Innovative Acceleration Award (UG3/UH3 Clinical Trial Optional) PAR-22-167 UG3/UH3
Notice of Special Interest (NOSI): Administrative Supplements for Research on Womens Health in the IDeA States NOT-GM-22-005 333
The Intersection of Sex and Gender Influences on Health and Disease (R01 Clinical Trial Optional) RFA-OD-22-028 R01
Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21 Clinical Trial Not Allowed) PAR-22-090 R21
Notice of Special Interest (NOSI): Developing Academic Research Enhancement Award (AREA) and Research Enhancement Award Program (REAP) for Institutions with an emphasis on Down syndrome research (R15 Clinical Trial Not Allowed) NOT-OD-22-136 R15
Notice of Special Interest (NOSI): NIH Research Project Grants on Down Syndrome (R01) for the INCLUDE (INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE) Project NOT-OD-22-123 R01
Notice of Special Interest (NOSI): Increasing Uptake of Evidence-Based Screening in Diverse Populations Across the Lifespan NOT-OD-22-178 R21, R01, UG3/UH3
Notice of Special Interest (NOSI): Addressing Evidence Gaps in Screening NOT-OD-22-179 R21, R01, R61/R33
NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) PAR-22-160 R03
Notice of Special Interest (NOSI): Climate Change and Health NOT-ES-22-006 R21, F31, D43
Instrumentation Grant Program for Resource-Limited Institutions (S10 - Clinical Trial Not Allowed) PAR-23-138 S10
Notice of Special Interest (NOSI): Promoting Mechanistic Research on Therapeutic and Other Biological Properties of Minor Cannabinoids and Terpenes NOT-AT-22-027 R21, R01, UG3/UH3
Notice of Special Interest (NOSI): Research on the Health of Sexual and Gender Minority (SGM) Populations NOT-MD-22-012 R01, K08, K99/R00
Notice of Special Interest (NOSI): Advancing Imaging, Device Production, and Clinical Capabilities in Digital Dentistry (R41/R42, R43/R44 Clinical Trial Not Allowed) NOT-DE-21-012 R43/R44, R41/R42
Notice of Special Interest (NOSI): Administrative Supplement for Continuity of Biomedical and Behavioral Research Among First-Time Recipients of NIH Research Project Grant Awards NOT-OD-23-032 333
Notice of Special Interest (NOSI): Research on Addressing Violence to Improve Health Outcomes NOT-OD-22-167 UG3/UH3, R34, R21
Notice of Special Interest (NOSI): Preventive Interventions to Address Cardiometabolic Risk Factors in Populations that Experience Health Disparities NOT-OD-22-154 R01, R21, R34
Notice of Special Interest (NOSI): Targeting the Endocannabinoid System for Brain Health and Acute and Chronic Diseases NOT-DA-22-048
Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed) PAR-24-038 RC2
Notice of Special Interest (NOSI): NIDCR Support for Research on the Physiological Involvement of Oral Cavity in Coronavirus Disease 2019 (COVID-19) NOT-DE-23-004
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-23-162 U01
Research With Activities Related to Diversity (ReWARD) (R01 Clinical Trial Optional) PAR-23-122 R01
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) PA-23-189 R16, R21/R33, R41/R42
Notice of Special Interest (NOSI): Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed) NOT-OD-23-170 332, 333, 666
NIDCR Notice of Participation in PAR-24-075 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Clinical Trial Not Allowed)" NOT-DE-24-009 R01
NIDCR Notice of Participation in PAR-24-076 "Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)" NOT-DE-24-010 R01
Notice of Intent to Publish a Funding Opportunity Announcement for Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) FOA NOT-DE-21-020
Notice of Information Reissuance of PA-18-932 Increasing Uptake of Evidence-Based Screening in Diverse Adult Populations (R01 Clinical Trial Optional) as a Notice of Special Interest (NOSI) NOT-OD-22-075
Notice of pre-Application Technical Assistance Webinar for RFA-DE-24-003 Collaborative Science to Achieve Disruptive Innovations in Dental, Oral and Craniofacial (DOC) Research (RM1 Clinical Trial Not Allowed) NOT-DE-23-016
Notice of Intent to Publish a Funding Opportunity Announcement for NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03 Clinical Trial Not Allowed) NOT-DE-22-008
Request for Information (RFI): Investigators interests in and barriers to research studies on the health effects of cannabis and its constituents NOT-AT-22-026
Notice of Corrected Application Forms for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-18-016
Notice of Intent to Reissue PAR-18-847 Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Prevention Research (R01- Clinical Trial Optional) and PAR-18-848 (R21 - Clinical Trial Optional) as a Notice of Special Interest (NOSI) NOT-OD-21-114
Notice of Change: Clarification of Budget for PA-20-227 "Administrative Supplements for Research on Dietary Supplements (Admin Supp Clinical Trial Not Allowed)" NOT-OD-20-148
Notice to Extend Expiration Date for PAR-19-145 "NIDCR Small Research Grants for Oral Health Data Analysis and Statistical Methodology Development (R03) NOT-DE-21-017
Notice of Change in Funding Opportunity Expiration Date and Eligible Organizations for "Assessment of Climate at Institutions (ACt) Award (RC2 - Clinical Trial Not Allowed)" (PAR-24-038) NOT-DE-24-007 RC2
Notice of NIDCR's participation in PAR-18-714, Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15-Clinical Trial Not Allowed) NOT-DE-18-015
Notice to Extend the Expiration Date for PAR-18-547, NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required) NOT-DE-20-037
NIDCR Guidance on Applications for Investigator-Initiated Clinical Trials NOT-DE-21-014
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required) PAR-23-270 R01