Clinical Trials Program

NIDCR is committed to identifying effective preventive, diagnostic, and treatment approaches for craniofacial, oral, and dental diseases and disorders. To advance these efforts, the Institute supports well-designed clinical trials (Phase I, II, III, and IV) that have the potential to improve oral and craniofacial health. These trials should provide scientific evidence that can be used for establishing or changing the standard of care, or for consideration of a change in health care policy.

Staff Contacts

Funding Opportunity Announcements

Title Staff Contact Opportunity Number Activity Code Expiration Date
Pilot Projects Investigating Understudied G Protein-Coupled Receptors, Ion Channels, and Protein Kinases (R03 Clinical Trial Not Allowed) RFA-RM-20-019 R03
NIH Directors New Innovator Award Program (DP2 Clinical Trial Optional) RFA-RM-20-012 DP2
NIH Directors Emergency Early Independence Awards (DP5 Clinical Trial Optional) RFA-RM-20-021 DP5
NIH Directors Early Independence Awards (DP5 Clinical Trial Optional) RFA-RM-20-014 DP5
NIH Directors Pioneer Award Program (DP1 Clinical Trial Optional) RFA-RM-20-011 DP1
NIH Directors Transformative Research Awards (R01 Clinical Trial Optional) RFA-RM-20-013 R01
NIH Directors Emergency Transformative Research Awards (R01 Clinical Trial Optional) RFA-RM-20-020 R01
Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UG3/UH3 Clinical Trial Required) RFA-HL-21-003 UG3, UH3
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-18-484 R01
NIDCR Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3) - Clinical Trial Required PAR-18-547 UG3, UH3
Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional) PA-18-591 C06, D43, D71
Change of Grantee Organization (Type 7 Parent) PA-18-590 C06, D43, D71
Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Admin Supp) PA 18-591 C06, D43, D71
Academic Research Enhancement Award for Undergraduate-Focused Institutions (R15 - Clinical Trial Not Allowed) PAR-18-714 R15
Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) PA-18-837 R41, R42, R43
Clinical Trials Development for Co-Occurring Conditions in Individuals with Down syndrome: Phased Awards for INCLUDE (R61/R33 Clinical Trial Required) RFA-OD-20-003 R33, R61
NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required) PA-19-091 R01
NIH Exploratory/Developmental Research Grant Program (Parent R21 Basic Experimental Studies with Humans Required) PA-19-092 R21
Research Enhancement Award Program (REAP) for Health Professional Schools and Graduate Schools (R15 Clinical Trial Not Allowed) PAR-19-134 R15
NIH Administrative Supplements to Recover Losses Due to Hurricanes Harvey, Irma, and Maria Under the Bipartisan Budget Act of 2018 Non-Construction (Admin Supp Clinical Trial Optional) PA-18-936 D43, D71, DP1
Urgent Competitive Revision to Existing NIH Grants and Cooperative Agreements (Urgent Supplement - Clinical Trial Optional) PA-18-935 K01, K08, K23
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) PAR-19-276 R03
Dissemination and Implementation Research in Health (R01 Clinical Trial Optional) PAR-19-274 R01
NIDCR Small Grant Program for New Investigators (R03 Clinical Trial Not Allowed) PAR-19-370 R03
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (SBIR) (R43/R44 Clinical Trial Not Allowed) PA-20-047 R43, R44
Development of Highly Innovative Tools and Technology for Analysis of Single Cells (STTR) (R41/R42 Clinical Trial Not Allowed) PA-20-025 R41, R42
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed) PAR-20-060 U01
Administrative Supplement for Research on Dietary Supplements (Admin Supp-Clinical Trial Not Allowed) PA-20-227 D43, D71, DP1
NIH Exploratory/Developmental Research Grant Program (Parent R21 Clinical Trial Not Allowed) PA-20-195 R21
NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed) PA-20-185 R01
NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) PA-20-207 R13