NIDCR Clinical Research Protocols

NIDCR conducts clinical studies on the NIH campus in Bethesda, Maryland. Currently, NIDCR-supported clinical trials are open or will soon be open for patient recruitment at the NIH Clinical Center. Below is a list of all clinical research protocols, including studies that are not open for recruitment.

Protocol	ClinicalTrials.gov Study Title	PI	Contact Person	NCT Number	Recruitment Status
01-D-0184	A Natural History Study of Bone and Mineral Disorders	Roszko, Kelly	Rita Meadows (301) 827-1138 rita.Meadows@nih.gov	NCT00024804	Recruiting
11-D-0172	The Pathogenesis and Natural History of Sjögren's Disease	Khavandgar, Zohreh	Eileen M. Pelayo (301) 594-3097 eileen.pelayo@nih.gov Blake M Warner, D.D.S. (301) 500-8063 blake.warner@nih.gov	NCT01425892	Recruiting
12-D-0100	Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)	Moutsopoulos, Niki	Laurie D. Brenchley (301) 451-2551 laurie.brenchley@nih.gov Niki M Moutsopoulos, D.D.S. (301) 435-7182 nmoutsop@mail.nih.gov	NCT01568697	Recruiting
13-D-0033	Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal	Lim, Jiwon	Sharon Mitchell (301) 451-9733 sharon.Mitchell@nih.gov	NCT01805869	Recruiting
15-D-0051	Characterization of Diseases With Salivary Gland Involvement	Beach, Margaret	Eileen M. Pelayo (301) 594-3097 eileen.pelayo@nih.gov Blake M Warner, D.D.S. (301) 500-8063 blake.warner@nih.gov	NCT02327884	Recruiting
15-D-0129	Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction	Chiorini, Jay	Active, not recruiting	NCT02446249	Closed to Recruitment
16-D-0040	Natural History of Craniofacial Anomalies and Developmental Growth Variants	Almpani, Konstantinia (Nadine)	Pamela M. Orzechowski, R.N. (301) 402-7373 ps363q@nih.gov	NCT02639312	Recruiting
18-D-0114	Denosumab Treatment for Fibrous Dysplasia	Boyce, Alison	Active, not recruiting	NCT03571191	Closed to Recruitment
18-D-0121	Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy Controls	Mays, Jacqueline	Licia Masuch (301) 435-9352 licia.masuch@nih.gov	NCT03602599	Recruiting
20-D-0094	Transmissibility and Viral Load of SARS-CoV-2 in Oral Secretions	Warner, Blake	Closed to enrollment; in data analysis	NCT04348240	Closed to Recruitment
20-D-0122	Safety, Tolerability, and Efficacy of CLTX-305 in Participants With Autosomal Dominant Hypocalcemia (ADH) Type 1	Gafni, Rachel	Active, not recruiting	NCT04581629	Closed to Recruitment
20-D-0131	Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjögren's Syndrome	Warner, Blake	Sasha Clary, (301) 529-7924 sasha.clary@nih.gov	NCT04496960	Recruiting
98-D-0145	Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome	Boyce, Alison	Lori C. Guthrie, R.N. (301) 594-0844 guthriel@mail.nih.gov Alison M Boyce, M.D. (301) 827-4802 alison.boyce@nih.gov	NCT00001727	Recruiting

Dental Clinical Research Core Contact

Beth Brillante, R.N., B.S.N., M.B.A.

Chief of Staff and Clinical Research Operations

Clinical Research Operations and Regulatory Management Office

Office of the Clinical Director

(240) 383-5108

bbrillante@mail.nih.gov

Nakiia M. Buyck

Chief of Clinical Staff

Office Manager

Credentialing Coordinator

Office of the Clinical Director

(301) 827-1647

nakiia.buyck@nih.gov