Genomic Data Sharing Policy

The NIH expects broad data-sharing for funded research that produces large-scale human or non-human genomic data, as described in the supplemental information to the GDS Policy. Examples of data types and sample sizes for human studies are shown in the table below. Please see the GDS Policy supplemental information for additional details.

 

The NIH GDS Policy: Examples of data types and sample sizes for human studies Number of Participants

SNP array data from >300K single nucleotide polymorphisms (SNPS)

(e.g., GWAS data)

1,000

DNA sequence data from < 100 genes or regions of interest (in general less than 34Mb)

(e.g., targeted sequencing)

1,000

DNA sequence data from ≥ 100 genes or regions of interest (in general greater than 34Mb)

(e.g., targeted sequencing, whole exome sequencing, whole genome sequencing)

100

Genome-wide RNA sequencing (RNA-seq) data

(e.g., transcriptomic data)

100

Genome-wide DNA methylation data

(e.g., bisulfite sequencing data)

100

Genome-wide chromatin immunoprecipitation sequencing  (ChIP-seq) data

(e.g. transcription factor ChIP-seq, histone modification ChIP-seq)

100

 

NIDCR extends this expectation to the following types of projects producing genomic data, regardless of the number of specimens or participants:

  • Human studies of rare diseases: Genetic & Rare Disease Information Center
  • The oral microbiome (archea, bacteria, viruses, and fungi).
  • Under-studied human populations.
  • Specific diseases or disorders: Human studies of Sjögren's Syndrome/xerostomia, or Temporomandibular Joint Disorder or related pain conditions.

Note that some journals have broad data-sharing expectations as well.

GDS Broad Sharing of Data

 

Questions?

Contact the Program Director for your area of research

 

NIDCR Genomic Program Administrator

 

NIDCR’s scope for the GDS policy will be reviewed periodically and updated as needed.

Last Reviewed on
February 2018