English

Overview

The SBIR and STTR programs are congressionally mandated, highly competitive federal funding mechanisms designed to stimulate technological innovation and foster the commercialization of research discoveries by U.S.-based small businesses. Both programs aim to strengthen the role of small businesses in addressing federal research and development (R&D) priorities and accelerating the translation of scientific breakthroughs into impactful products and services.

Overview

The Oral Microbiology Program supports basic and translational research on the role of microbes in oral disease. Topics include examining mechanisms of pathogenesis, prevention, diagnosis, and treatment of microbial infections, as well as research on emerging conditions and diseases and our understanding of the oral microbiome. The National Institute of Dental and Craniofacial Research encourages research on understanding infections that emerge within the oral cavity based on the capacity of microbial pathogens to adapt to the unique oral environment.

Overview

The Oral and Salivary Cancer Biology Program supports basic and translational research to improve detection and treatment of cancers of the oral cavity, pharynx, and salivary glands. The program aims to advance knowledge in mechanisms that influence tumor initiation, promotion, and progression, as well as development of innovative biomarkers and diagnostic technologies to improve medical decision and treatment evaluation. Examples of supported research include:

Overview

The Neuroscience of Orofacial Pain and Temporomandibular Disorders Program supports basic and translational research on orofacial pain and neuropathies, temporomandibular joint and muscle disorders, development of biomarkers for diagnostics and prognostics, and development of therapeutics. Basic and translational studies on nervous system mechanisms and regulation in craniofacial conditions and disorders are also of interest.

Overview

The Dental Materials & Biomaterials Program at the National Institute of Dental and Craniofacial Research advances the discovery, design, and translation of innovative materials, devices, and integrated systems to restore, preserve, and optimize dental, oral, and craniofacial (DOC) health.

Overview

The Tissue Engineering and Regenerative Medicine Program supports basic and translational research employing interdisciplinary approaches for the reconstruction, repair, and regeneration of dental, oral, and craniofacial (DOC) tissues that have become impaired by disease or injury.